what type of people does cbd oil not work for

CBD: a marijuana miracle or just another health fad?

A aron Horn first came across cannabidiol, or CBD, about three years ago in Glastonbury – the town, not the festival. “I found it at this amazing hemp shop, Hemp in Avalon,” recalls Horn, a musician who is now 35. “It’s run by a guy called Free. His last name is Cannabis. He changed his name by deed poll to Free Cannabis.” Horn bought a tube of high-concentration CBD paste – “it comes out like a brown toothpaste, almost” – and it was recommended he put a tiny dot on his finger and pop it in his mouth.

Horn’s adult life had been spent in the shadow of a horrific accident that took place when he was 22. In June 2006, he had been shooting at a target with an air rifle in the garden of his family home; his parents are the music producers Jill Sinclair and Trevor Horn. Horn didn’t realise his mother was nearby, and a stray pellet lodged in her neck and severed an artery. Sinclair experienced hypoxia, which caused irreversible brain damage, and she spent years in a coma before dying in 2014.

After the accident, Horn did sessions of cognitive behavioural therapy, which he found helpful. He didn’t take antidepressants, because he was concerned about the side-effects; he did smoke cannabis, though he didn’t always like feeling stoned. “I suffered from some PTSD symptoms, flashbacks,” he says. “And some other issues.”

Almost immediately, Horn found using CBD lifted his mood. Cannabidiol is a non-psychoactive chemical found in marijuana and hemp plants. It will be present if you smoke a joint, but is often overwhelmed by one of the other 100-plus cannabinoids found in cannabis: THC (tetrahydrocannabinol). This is the ingredient that mainly has mind-altering properties, but also now has worrying links with mental illness and violence. CBD products are allowed to contain only traces of THC, which makes them legal, and devotees claim that they have many of the benefits of cannabis with none of the drawbacks.

“CBD has helped me across the spectrum,” says Horn. “It definitely helped in social situations, if I was finding it hard to be around people. It brings you more into the moment. I felt more relaxed.”

Horn is bouncy and enthusiastic; for someone who spends a fair amount of time meditating, he seems to have a hard time standing still. Our conversation takes place in his shop, LDN CBD, which he opened in Camden last July with a friend, Joe Oliver. CBD has been available to buy for a while – not only in independent shops such as Hemp in Avalon but also, since early 2018, in nationwide chains such as Holland & Barrett – but Horn contends that this is the elixir’s first dedicated boutique in the UK. It is certainly a long way from the traditional head shop: bongs and Rizlas have been swapped for white walls, reclaimed-wood floors and uncluttered shelves sparsely dotted with CBD oils, pastes and pills, and on-trend houseplants. A 10ml bottle of 3% CBD oil costs £25. Horn sees his target customer as anyone interested in wellness, more than counter-culture stoners. Downstairs are two studios for yoga, reiki and CBD massages.

‘CBD will change culture’: Aaron Horn at his LDN CBD boutique in Camden. Photograph: Suki Dhanda/The Observer

If LDN CBD is the first, it certainly won’t be the last. Interest in CBD products is exploding: it is 2019’s avocado toast, this moment’s turmeric shot. Except there is a crucial difference. If CBD does what its advocates suggest – or even a fraction of it – this all-natural, side-effect-free, widely available chemical could genuinely be the wonder drug of our age. Adherents claim it is “adaptogenic” – that is, a natural, non-toxic substance that regulates your stress response – and it’s not hard to find people who will tell you it has helped with anxiety, acne, schizophrenia, menstrual pain, insomnia and even cancer. There are also dozens of CBD cosmetics products, CBD juices and coffees are now a thing, and some find it useful as a sexual lubricant. Bizarrely, it has taken off in pet products, too: everything from chews for anxious dogs to treating life-threatening ailments. New products include truffles, bath bombs, moisturisers, ice cream, CBD-infused spring water (available from Ocado) and, naturally, CBD turmeric oil. CBD doesn’t have an especially strong taste – fans call it “nutty”, others “boggy” – which means it can be added to food without overpowering it.

Much of this activity takes place online, so it’s hard to gauge the number of users, but one estimate, from the Cannabis Trades Association UK, suggested that there were 250,000 cannabidiol consumers in this country in 2017, double the number from the previous year. For Horn, CBD is simply the perfect drug for the way we live now. Something to take the edge off. Just as you might find a couple of off-licences on high streets now, Horn believes it won’t be long before there are two shops selling cannabis products.

“CBD will change culture,” he predicts. “People are less interested in drinking in bars, getting really drunk, feeling shit the next day, letting their body down, having issues with their body because of that. The shift is happening: more people are interested in eating healthier, living healthier, and this is part of that. It changes it a lot more than the new iPhone or another pair of trainers, or everything we’ve had since the 90s that’s just different versions.

“It will drastically affect the way the world looks in 20 or 30 years and the way we live.”

But does it work? And does taking CBD do us any good? Philip McGuire is a professor of psychiatry and cognitive neuroscience at King’s College London; he has a special interest in psychosis and started looking into cannabidiol about 15 years ago. One of the first experiments he worked on looked at how cannabidiol works in the brains of healthy people in comparison with the impact that THC has. The results were categoric. “We basically showed that the two compounds have opposite effects on brain function,” says McGuire. “So when THC is making you psychotic, it stimulates certain bits of the brain. And in these areas of the brain, CBD has the opposite effect, essentially, in the same people.” To boil it down: “CBD and THC seem to be pushing in opposite directions.”

In the past five years, McGuire has moved on to do clinical trials of cannabidiol in patients with psychosis, or people who are vulnerable to psychosis. The tests have been done against a placebo, double-blind, and again the results are very encouraging. “We’ve done two phase-two trials and, in both of these, found that cannabidiol reduced psychotic symptoms more than the placebo did,” he says. “So it wasn’t a placebo effect, it really did reduce psychotic symptoms.”

McGuire’s work is ongoing, but he doesn’t hide his excitement about CBD. “It’s the hottest new medicine in mental health by some margin,” he says. “There’s huge interest in it as a potential new treatment.”

Mental health is just one area of investigation for those studying cannabidiol. Perhaps the best-known user of CBD – if you discount Gwyneth Paltrow, who has collaborated through her lifestyle website Goop with the MedMen cannabis store, and a handful of Hollywood actresses who have said they use the oil to reduce the discomfort from wearing high heels on the red carpet – is Billy Caldwell. The 13-year-old from County Tyrone, Northern Ireland, who has epilepsy, made headlines last summer when his cannabidiol medicine was confiscated at Heathrow. After a public outcry, the home secretary, Sajid Javid, intervened and medicinal cannabis oil can now legally be prescribed in the UK. It’s been far from straightforward for the family: Billy recently spent three months in Canada, where medicinal cannabis use is less regulated, but he finally returned home in February.

Charlotte Caldwell and her son Billy, who uses a purified form of cannabidiol to control his epilepsy. Photograph: Yui Mok/PA

His medicine is Epidiolex, a purified form of cannabidiol that contains less than 0.1% THC. It has been developed by a UK company, GW Pharmaceuticals, and is recommended for the treatment of two of the rarest and most severe forms of epilepsy: Lennox-Gastaut syndrome and Dravet syndrome. When it was cleared for use in the US last year, the president of the Epilepsy Foundation called it “a true medical advancement”. Treatment does, however, come at an eye-watering cost; in the US, GW estimates $36,000 (£28,000) per patient annually, though the company notes that the potential future price in the UK might be different.

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Still, it is hard not to feel that cannabidiol has rare potential as a medicine, and we are only just scratching the surface. McGuire is cautiously optimistic that it’s “as good as it seems to be”. For one thing, in tests so far, CBD does not seem to have produced any major unwanted effects in patients. “In mental health, that’s a big deal,” says McGuire. Another strand is that cannabidiol seems to act on different transmitter systems in the brain to existing treatments. That would make it a new class of treatment, which is significant because it means that, if previous medications or approaches haven’t worked, this one might.

One suspicion about cannabidiol is that it is an impossible panacea: some, for example, claim CBD makes them more relaxed; others that it sharpens their mind to focus on complex work problems. Can it really do both? But, for McGuire, this is less a contradiction and more an indication that we don’t yet know what CBD is capable of and how best to use it. “One of the interesting things about the endocannabinoid system in the body is that it’s not just in the brain but also all over the body,” he explains. “And cannabidiol also appears to have beneficial effects on metabolism, on the immune system and liver function, in addition to its mental health effects.”

McGuire would now like to do a worldwide trial of cannabidiol in large samples to see whether it can be a medicine, not just a research tool. “Patients with psychosis have a life expectancy that’s about 20 years shorter than normal, and that’s because psychosis is associated with poor physical health, especially cardiovascular health,” he says. “And it’s possible that – this has never been tested – but another benefit of cannabidiol in these patients is that it could help with their physical health problems.”

Hearing these testimonies, it would seem perverse, even neglectful, not to use CBD, but where to start? One option is High Tea at Farmacy, a plant-based restaurant in west London. On the menu are a CBD-infused vodka cocktail, CBD truffles (tahini and dark chocolate, and basmati and coconut) and a pot of hemp leaf tea. With extras, it costs £42. “You don’t technically get high from it, it’s just a great play on words,” says Camilla Fayed, who opened Farmacy in 2016. “It definitely draws people in.”

Fayed, the 34-year-old daughter of former Harrods owner Mohamed Al Fayed, first came across CBD in the US in an oil made by Charlotte’s Web. The company is named after Charlotte Figi, a 12-year-old with Dravet syndrome, whose story has many echoes of Billy Caldwell’s. Figi, too, found that her seizures were significantly reduced by taking medical cannabis. Charlotte’s Web was developed in 2011 by six brothers (Joel, Jesse, Jon, Jordan, Jared and Josh Stanley) who crossbred a strain of marijuana with industrial hemp to make products that are high in cannabidiol and low in THC. Its oils start with the entry-level “full strength”, which claims 6.65mg of CBD per ml, and go up to “maximum strength”, which has 60mg of CBD per ml.

The ‘high tea’ at Camilla Fayed’s restaurant Farmacy. Photograph: Robin Goodlad

For Fayed personally, CBD helped with memory and concentration. “And tiredness,” she adds. “I’ve got two kids, I run a business, we all need a boost. I’d rather have that than a big black coffee every two hours or whatever.” And it made a difference? “Absolutely. General concentration, sleeping better, just an all-rounder. From taking it, in about six weeks, I could basically track the difference in the way it made me feel. So I just thought: ‘Let’s introduce this to the commercial market.’”

Farmacy started in April 2017 with cannabidiol cocktails. One of these, OMG, is delivered in a syringe and blends flaxseed oil, grapefruit and “wildcrafted” CBD. When it arrives, it’s not immediately clear whether you decant it into a shot glass or shoot it straight in your mouth. “Well, plenty do,” advises Fayed. “It’s very Instagrammable.”

Fayed – in common with Horn – is not allowed to make medical claims about the cannabidiol products she sells. (Horn also points out that he cannot advise on dosage and would never recommend that a customer comes off prescribed medication to use CBD.) But at Farmacy, Fayed often hears that the CBD cocktails impart a more ambient buzz on the drinker. “We have a lot of repeat customers, so for us that’s definitely a winner,” she says. “And especially with the alcohol, there’s that adaptogenic effect in the alcohol: people feel less drunk or feel their hangover is less brutal the next day if you’re going to have two or three.”

It can be tempting to see CBD as a triumph of hype or marketing, and Fayed advises caution: for starters, it needs to be really high quality. Farmacy’s CBD comes from Spirit of Hemp in Forest Row, on the edge of the Ashdown Forest in Sussex. It uses organic hemp, hand-harvested in Switzerland and Austria, and after the extraction process, it reintroduces steam-distilled terpenes (what Spirit of Hemp calls “the life force, the quintessential fifth element or the spirit of the plant”). “It’s a real shift in understanding of what Mother Nature has given to us,” she says. “The veil has lifted finally on its benefits, and it’s definitely the beginning of something really big in the natural medicine world. So I don’t think it’s a trend, it’s here to stay.”

Something, though, is missing from the CBD story: proof. And this is the detail that really worries Professor McGuire. He points out that in the trials on psychosis that he’s been involved in, patients might be given 1,000mg of pure cannabidiol in a tablet; the medication for the pharmaceutical treatment of epilepsy could be 2,500mg. Compare this to a drink advertised as CBD coffee or a brownie, which may contain, for example, 5mg of CBD. And there is the issue of bioavailability: how much of a drug your body actually takes into your gut. “Of that 5mg, you might absorb 1mg or less,” says McGuire. “Or none.”

McGuire sighs. “If you look at the labels of the street products, it’s very difficult to know what’s actually in them. And there’s a huge variety between products, so that’s a really important message to get across: that a lot of what people may be taking in good faith may be having absolutely no effect at all, other than a placebo effect.”

The distinction for McGuire is that CBD is a nutriceutical – in common with minerals and vitamins – not a pharmaceutical product. This is in large part due to its origins. Cannabidiol was not developed as a new blockbuster drug by a pharmaceutical giant or a medicine to which nobody else had access. Instead, the compound has emerged relatively organically, and pretty much anyone can produce a version of CBD without infringing patent laws. (GW can only patent what is called the “formulation” of Epidiolex.) If you’re no fan of big pharma, this has some advantages: CBD can become widely available and competitively priced. But the downside is that cannabidiol products are not subject to the clinical trials and randomised, double-blind assessments that we might expect from a supplement we are taking to improve our health.

“I’m not trying to be a killjoy,” says McGuire, “but, especially in mental health, the size of the placebo effect is enormous. That’s not to dismiss it, but that’s why in clinical trials, if you don’t give half the people in the trial a placebo, it’s considered junk. It’s not publishable, it’s not taken seriously because, in mental health, the placebo effect can produce a 40% change in symptoms.

“It’s like Prince Charles and homeopathy, it’s a joke. Some of these products have got such tiny quantities that they could never work.”

CBD is now readily available in many forms in high-street shops. Photograph: MediaWorldImages/Alamy

McGuire concedes that different CBD products will have varying strengths, and he also acknowledges that he cannot say they don’t have an effect – it’s simply that we don’t know for sure either way. And clearly others share his concern. In February, New York became the first major American city to impose a ban on CBD edibles in restaurants. “Until cannabidiol is deemed safe as a food additive,” said a spokesperson from the New York City Department of Health, “the department is ordering restaurants not to offer products containing CBD.” From July, a fine of up to $650 (£500) could be imposed.

There are clear health risks with any unregulated product. The reason that Epidiolex is really expensive, McGuire explains, is that isolating cannabidiol is “intrinsically difficult to do”. He fears that over-the-counter CBD products could have higher levels of THC than either advertised or desired. A 2017 study in the US looked at 84 samples of CBD oils, tinctures and liquids available online and found that only 26 of them contained the amount of CBD claimed; worryingly, 18 of them had more THC than they said. “THC makes you psychotic and anxious and impairs your cognition,” warns McGuire, “so it’s very important that’s not in anything that’s being consumed.”

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A longer-term danger, however, is that people will lose interest in cannabidiol, perhaps because they don’t find it has any effect in the product they try, and it will languish as one of those trends we like to make fun of. “I’m slightly anxious that the confusion will muddy the water,” says McGuire. “People will try these homeopathic versions and find that it doesn’t do anything, and then they assume that cannabidiol doesn’t work. Then it will damage the therapeutic potential of what could be a very useful new medicine. It’s a bit like if somebody sold Nurofen at one-hundredth of the effective dose and then found it didn’t work. You could end up dismissing Nurofen as a useful treatment.”

Anecdotal evidence suggests that CBD use skews towards the young and female, but Horn at LDN CBD hasn’t found a gender divide and he has lots of older customers in his shop. He often hears that CBD oil helps with their arthritis, and sometimes that they have been able to open jars for the first time in years. Horn has even got his granny on CBD. He is currently raising funding for two more stores in London, and he would like to have another 10 stores in the major cities of the UK. “Most towns with a Holland & Barrett could have a shop like this,” he predicts.

Horn’s CBD comes from Lithuania and is sold as “ethical and organic”. He accepts that the doses of CBD in the products are significantly lower than might be used in medication or clinical trials, but he’s not sure how relevant that fact is. “From what they are finding out about the endocannabinoid system, little and often of the right product is probably as effective as a huge amount,” he says.

Alongside Horn is LDN CBD’s store manager, Florence Cannon-Orderly, a 30-year-old yoga instructor. She started using CBD to help with premenstrual symptoms. “It’s got much better now, but for a good half of my month I feel extremely challenged,” she says. “CBD has given me the therapeutic benefit without getting stoned.”

Why CBD Oil Won’t Work for Everyone [Answered]

CBD sales are escalating to the point where they are expected to reach approximately $20 billion globally by 2024. It is one of many interesting CBD statistics:

  • There are almost 900 CBD brands in the American market.
  • An estimated 40% of Americans have expressed an interest in using cannabidiol.
  • Up to 75% of CBD brand founders or general managers are female.
  • 90% of hemp-derived CBD consumers in the United States believe weed has medical benefits.

Here is a quick look at just how quickly CBD sales have grown in the United States, plus a projection of the next three years:

Potential CBD Benefits

The list of purported benefits varies from a reduction in seizures in people living with epilepsy to relief from anxiety and stress.

Pain and vomiting

May help reduce symptoms related to pain, vomiting, and nausea

Impacts endocannabinoid receptor activity, thus reducing inflammation and treating pain related to conditions such as arthritis, multiple sclerosis, and fibromyalgia

Potentially helps you to relax, feel calmer, and may also boost mood

CBD could minimize sebum production, the primary cause of acne

Possibly reduces muscle spasticity and seizures

CBD is linked with the ability to lower high blood pressure and reduce oxidative stress

However, CBD does not work for everyone. Therefore, we advise you to steer clear of any website, organization, or CBD seller that claims the cannabinoid is a cure-all. Research into CBD is ongoing, and while it has uncovered plenty of exciting things, scientists are, at present, unable to conclude the exact efficacy of cannabidiol.

If you have tried CBD and it did not have the effect you desired, there are several reasons. In this guide, we provide explanations for six of the most common.

1 – Low-Quality CBD Products

Due to its relatively new prevalence, the CBD market is still very much like the wild, wild West; heavily unregulated. CBD is not FDA approved, meaning it is not subject to many of the strict rules that other health products and supplements are.

Sometimes, dishonest companies will try to make a quick buck by selling CBD or hemp oil made from poor quality ingredients or with very little CBD content within the products at all. Ideally, look for CBD products that are made with organic hemp and are free from pesticides, insecticides, chemical fertilizers, and other carcinogens.

The way you can make sure a company’s products are free from all those nasty ingredients is by reviewing their third-party lab reports (if they have them). Reports conducted by an unaffiliated lab will give you an honest breakdown of what is featured in a CBD product.

Unfortunately, not every brand decides to quality control and test its products. In 2017, researchers examined the quality of online available CBD extracts. The study published in JAMA found that a mere 31% of products contained the CBD listed on the label within a margin of 10%. That means an entire one-quarter of the products tested had less CBD than its company claimed.

Another concerning factor was that 21% of products also had THC, which poses a massive problem if you are required to take a drug test.

As time went on, we were hoping the CBD marketplace was becoming more transparent, but in 2019, an NBC 6 Miami, Florida team bought 35 CBD products from seven different brands and had them sampled. The results? 20 of the products contained less than half of the cannabidiol content claimed! Even worse, some of the products contained zero CBD. One representative example was a bottle of gummies expressing 15mg of CBD on the label, which results showed only actually contained 2.2mg.

Therefore, if CBD is doing nothing for you, it might be a case of the product not containing much cannabidiol to begin with! Begin your CBD search by looking for reputable brands like PureKana, Premium Jane, Green Roads, Elixinol, and Provacan if you are a UK customer.

Incidentally, Green Roads was one of the brands tested by NBC 6. It was one of the few companies that made the grade. The company’s founder, Laura Baldwin Fuentes, said she spends over $1 million each year to perform three levels of testing. Remember, CBD companies are not legally required to test their products. Only buy from brands that have third-party lab reports backing up their claims.

2 – Dosage & Potency

One thing we DO know about CBD is that it affects everyone differently. Factors such as your age, weight, gender, lifestyle, general health, and the condition you aim to treat all play a role in how it affects you. As a consequence, your best bet is to begin with a low dose to see how CBD affects you. If you are not satisfied with the results, up the dosage accordingly until you reach the minimum recommended dose.

It is entirely possible that 10mg of CBD per day does nothing, but 20mg a day has an effect. As a general rule of thumb, begin with 1-6mg per 10 pounds of body weight, depending on your pain level. For example, you will take far more if you have severe pain when compared to mild discomfort.

Here is a quick table outlining rough estimates based on pain level and how much you weigh.

Weight Mild Pain Medium Pain Severe Pain
0-49 pounds 1-6mg 3-9mg 6-12mg
50-99 pounds 5-20mg 12-49mg 30-60mg
100-149 pounds 10-30mg 21-74mg 50-90mg
150-200 pounds 15-40mg 31-99mg 75-120mg
201-250 pounds 20-50mg 41-124mg 105-150mg
251-300 pounds 25-60mg 51-149mg 125-180mg

As you can see, the range is vast. Begin at the lower end and work your way up.

Understanding the potency of the CBD product in question is imperative if you aim to determine your daily dosage. For instance, a bottle that contains 30ml of liquid and 1,200mg of CBD contains 40mg of CBD per ml. Most CBD tincture bottles contain a 1ml or 2ml dropper. Read the label carefully to see how many drops the dropper holds.

It is all too easy to miscalculate your dosage and use too little or too much CBD.

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3 – You Have Inadvertently Developed a Tolerance

Those who consume cannabis often can take a tolerance break (T-break) when it feels as if marijuana is no longer offering them the same impacts as prior. After a short period of abstinence from the plant, they return and once again get to reap cannabis’s rewards. Like with cannabis, frequent CBD consumers may also need to take a tolerance break if they find cannabidiol is no longer assisting. It IS completely feasible that one could develop a tolerance to CBD, though they would probably have to consume a significant amount to reach that point.

A December 2018 study presented by Shimrit Uliel-Sibony expressed a trial in which 92 patients have ‘treatment-resistant’ epilepsy. They all were placed on a CBD treatment protocol, where cannabidiol was administered in especially high doses. The researchers found almost one-third of the patients developed a tolerance to the CBD.

Like any substance , i t is possible to develop a tolerance to CBD, though it’s uncommon.

The reports of this study certainly are not encouraging if one is consuming long-term high doses of CBD for epilepsy, but there is a sliver of hope about their findings. The dosage administered and the time frame of administration were both far above the amounts most individuals would practice. Also, it took an average of 7 months for each study participant to reach tolerance. Additionally, the mean dosage was 12.6mg per kg per day.

Just to put these numbers in perspective, a person weighing 154 pounds would need to consume around 882mg of CBD daily to build up such a tolerance, as represented in this study.

There is a short list of why CBD won’t work for you, but developing a tolerance is probably the least likely. Nonetheless, if you are, like many average consumers taking between 30mg-120mg of CBD per day, and you notice a tolerance building, consider refraining from cannabidiol use for one to two weeks and monitor closely how you feel.

4 – Genetics

Even if CBD is immensely popular, there is no actual evidence that it is guaranteed to work for every single individual. Sometimes, a person’s genetic makeup may be preventing them from benefiting from certain cannabinoids, hence why they may not have as positive a reaction as others.

In November 2016, a study conducted by Smith et al. and published in PLoS One examined rare genetic variants in the core endocannabinoid system (ECS) genes. Their research expressed that up to 20% of humans have a genetic mutation that enables us to generate a level of endocannabinoids that is above average. People who are presented with this genetic mutation are often shown to be less anxious, but they also do not receive as much relief when consuming cannabidiol products.

5 – Physical & Psychological Health

Also, there are biological factors at play. Initial research suggests that women are more sensitive to the cannabinoids in weed and hemp than men. As a result, they are more likely to experience pain relief than their male counterparts. It is also worth noting that men are larger than women on average. Since a person’s size dictates the effect of CBD, it stands to reason that men need more CBD to treat conditions such as chronic pain.

Interestingly, the menstrual cycle plays a role in how cannabinoids impact women. Studies going back to the early 1980s show THC works closely with the hormone, estrogen. As a result, marijuana is at its most potent when a woman’s estrogen levels are at their highest. It is less clear whether CBD has the same impact.

If you don’t believe that cannabinoids impact each person differently, consider alcohol consumption and tolerance. You may feel okay after four glasses of wine, while someone else may lose their balance after consuming the same amount. Once again, this is due to, the ECS. Factors such as diet, lifestyle, stress, and genetics determine the impact of CBD.

If you want CBD to work more efficiently, take a look at your fatty acid intake. A study by Kim, Li, and Watkins, published in Nutrition in June 2011, stated that a diet high in Omega-6 polyunsaturated fatty acids would result in increased ECS activation. Increased Omega-3 intake helps modulate the activation of target receptors in the ECS.

Feel Good Already? CBD May Not Help

Oddly enough, if you are in excellent physical and psychological shape, CBD may not provide much assistance. From what we know about the cannabinoid, it works best in individuals with endocannabinoid ‘gaps.’ Do you take aspirin when you don’t have a headache or ibuprofen when you don’t have inflammation?

If you have a condition such as fibromyalgia, for example, you are in dire need of cannabinoids. As such, using CBD should help alleviate at least some of the pain. When you use CBD medicinally, it results in numerous chemical reactions within the body that help restore a state of balance or homeostasis. If your body is already in this state, it stands to reason that CBD won’t give you much of a boost.

It is the same scenario when it comes to mental health. Individuals with depression, PTSD, anxiety, or a similar issue possess a chemical imbalance in the brain. When you use CBD, it potentially restores the chemical balance and improves how you feel. Once again, would you use anti-depressants if you already felt good and did NOT suffer from depression?

6 – You Are Not Using a Full-Spectrum Product

There are plenty of cannabidiol sellers offering CBD isolate. While there is nothing inherently wrong with these products, some research suggests they are not as effective as full-spectrum products. This type of item contains dozens of cannabinoids aside from CBD, including CBG, CBC, and CBN; not to mention scores of terpenes.

Research shows that cannabinoids, terpenes, and flavonoids work better together in a process known as the entourage effect. You can even combine CBD with THC if you don’t mind feeling a little stoned (CBD helps counteract the psychoactive effects of THC somewhat) and live in a legal state.

7 – You’re Not Being Patient! (Unrealistic Expectations)

Once again, the lack of regulation in the CBD industry is a problem here. Too many users believe the hype and think cannabidiol will provide a ‘cure’ for their medical complaint. It is best if you alter your expectations. If you have suffered from crippling pain for years, don’t be disappointed if CBD doesn’t eliminate it completely. It is far more likely that the cannabinoid will reduce the severity of the pain to a point where life is less miserable.

If you expect a 90-100% reduction in pain and ‘only’ get a 50% reduction, you will ‘feel’ cheated. In reality, you are much better off than you were before!

Don’t expect immediate results when using CBD; patience and consistency are key.

Also, don’t expect a situation where you use CBD and feel ‘better’ within five minutes! Many of the possible effects, such as anti-inflammatory properties, take weeks of daily use to notice. Remember, the CBD interacts with the cannabinoid receptors of your immune system and ECS to trigger a response from the cells.

‘Balance’ in the body is not something that happens overnight. Be patient and wait until you finish a full CBD oil bottle, or use a CBD product daily for a month before judging its efficacy.

A Chart Highlighting and Summarizing Each Pitfall

  • Lack of regulation
  • Not lab tested
  • Contains minimal CBD
  • You are not taking enough CBD each day
  • The CBD product is weak
  • You fail to find your minimum useful dose
  • Potential to develop a tolerance when taking a lot of CBD for a long time
  • Most likely to affect patients with epilepsy
  • The least likely reason
  • Healthy individuals may not benefit as much from CBD
  • A genetic mutation could result in increased endocannabinoid production, thus reducing the impact of CBD
  • Women may experience more significant pain relief from CBD than men
  • CBD isolate is likely not as effective as full-spectrum products
  • Try a product that contains numerous cannabinoids and terpenes
  • The entourage effect suggests that cannabinoids work better together
  • CBD does not work overnight
  • You may not feel the effects for weeks
  • Don’t harbor unrealistic expectations

Final Thoughts on Whether CBD Oil Will Work for Everyone

If you have used CBD and are disappointed in the perceived lack of effects, look through this article to see if any of the points apply to you. It might be something as simple as not using a high-quality product, or else you don’t use enough CBD each day. Alternatively, you may be unlucky, and your genetic makeup means cannabinoids don’t impact you in a similar way to others.

On the plus side, it may not work because you are in excellent health. That’s hardly the worst thing in the world.