side effects of cbd oil for dogs

CBD Oil for Dogs: Common Side Effects

We know you take being a dog parent seriously. As such, you are meticulous when it comes to your dog’s diet, health, and wellness. The more we know about what’s in our dog’s food and in the medications and supplements we give to them, the more we know we can potentially do better than we’ve been doing, to provide healthier, higher quality options that deliver better results.

Since the Farm Bill of 2018 was passed, the production and manufacturing of commercial hemp has been legalized federally, and the availability of hemp products for our pets has increased exponentially. While this is definitely a giant step in the direction of focusing more on traditional, holistic remedies for our dogs’ ailments, it may leave you with questions as to what these options are and whether or not they are actually safe.

We understand. We’re dog parents, too, and as such, we’re committed to creating the safest products with the highest quality ingredients for our dogs. This is why we created a specially formulated CBD tincture designed specifically for your pet.

Our tinctures are filled with CBD oil that is hemp-derived and American grown. We subject our tinctures to the highest standards of third party laboratory testing to ensure they not only contain the quality and concentration of CBD we say they do, but they also don’t contain anything they shouldn’t, like harmful pesticides or chemicals.

If you have questions about CBD oil for your dog, we’re here to help answer your questions so you can make an informed decision if CBD oil is a good option for your dog’s health and wellness routine.

What Exactly is CBD Oil?

There’s a lot of confusion surrounding what CBD oil and what it is not. CBD is the abbreviation for “cannabidiol.” Cannabidiol is one of over 100 compounds found in the hemp variety of the Cannabis sativa plant. These compounds, called cannabinoids, have impactful health benefits for your pet that are best realized when they are extracted from the cannabis plant together.

When all cannabinoids from the plant work together concurrently, your pet receives the maximum benefit the plant has to offer, and that benefit is referred to as the entourage effect.

If you’re wondering if CBD oil can get your dog “high,” rest assured it cannot. This common misconception about CBD oil, that it can somehow make your animal high, is born from confusion between CBD and another popular cannabinoid, tetrahydrocannabinol, or “THC.” This is the cannabinoid responsible for producing the euphoric “high” a user feels when they use marijuana. It’s worth noting that commercially grown hemp (the kind that produces CBD oil) produces a very low amount of THC.

By federal law, commercially manufactured CBD products, including those for your pet, must be made from hemp plants that contain less than 0.3% THC, which is not enough to produce a “high.” It’s important that a CBD product contain this trace amount of THC, however, as there is evidence to support the presence of THC as a necessity to deliver the entourage effect. Full spectrum CBD oil is the only kind of CBD oil that contains this trace THC, so it’s important to use this type of CBD oil when seeking optimal results. A CBD isolate oil cannot produce the entourage effect, and may not be as beneficial for your pet.

How Does it Affect My Dog?

CBD may have an instantaneous effect on some dogs, though it may take several doses or even weeks to notice changes in other dogs.

Once you’ve given your dog CBD oil, you may be able to see results within minutes. Every animal is different, and some dogs are more immediately receptive to the effects of CBD oil than others. Your dog’s response to CBD oil will depend on the concentration and amount of CBD oil you give as well as the dog’s individual physiology.

A typical dose of CBD oil will last for approximately eight to twelve hours. Every dog is different and how your dog responds to CBD oil may not be exactly the same as another dog’s response.

Why Should I Give My Dog CBD?

CBD has a wide range of potential benefits when given to your dog. Here are some of the main reasons people administer CBD to their pets.

  • CBD oil can support joint health.
  • CBD can support normal GI function.
  • CBD can support normal brain function.
  • CBD can promote calmness .
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What Are Common Side Effects?

Before starting any new regimen with your pet, you should always consult a veterinary professional . The team at VETCBD is knowledgeable and experienced, but your specific veterinarian knows your animal personally, and should be made aware of any changes in their overall routine.

CBD oil is generally very well tolerated by canines, with very few side effects. When given in low doses, you will likely not notice any adverse side effects with CBD treatment. However, if your dog experiences a side effect from CBD oil treatment, it will likely be among the following:

  • Drowsiness. In a small portion of animals, CBD can cause them to be sleepy.
  • Vomiting and/or diarrhea. This is a rare side effect and may indicate another issue altogether. However, if you suspect your CBD oil treatment is adversely affecting your dog’s GI tract, stop treatment and contact your veterinary professional.

What To Look For in CBD Products for My Dog?

If you’re ready to try CBD oil as a holistic supplement for your dog, there are some things you should know before making a purchase. Not all CBD oils are created equally, and it’s important to know what you’re buying.

For optimal effects, your dog’s CBD oil should be full spectrum so they are able to obtain maximum CBD oil benefit. Our tinctures are full spectrum where the CBD oil is extracted from responsibly grown American hemp and uses organic extra virgin olive oil as the carrier oil.

It’s important to verify the quality, safety and potency of the CBD product you’re purchasing. Third party testing ensures that the CBD products you use for your dog include the exact type and amount of ingredients the manufacturer says they do. We triple-test our products throughout the manufacturing process with independent laboratories for third party testing to ensure we’re achieving the most effective cannabinoid profile for your pet. Additionally, this layer of testing also ensures that our products do not contain any unwanted chemicals, pesticides, or other ingredients that could cause harm to your pets.

Being generally well-tolerated and safe for most dogs, it’s worth giving CBD oil a try to help support your dog’s overall wellness and health. Explore VETCBD Hemp today and see all your options to help your dog thrive.

CBD Oil for Dogs: Side Effects and Risks

When using medicine or supplements for our dog, we wonder what the side effects could be. Since we always want to do what is best for our dog, we tend to ask ourselves about the potential side effects of using CBD oil.

If your dog is suffering from cancer, seizures, anxiety, hair loss, or itchy skin, and you’ve researched holistic or supplemental relief, then you have probably read about CBD oil. CBD oil helps dogs feel calm while providing anti-inflammatory properties for pain and irritation management. Paws Elite has had good feedback on the result of their CBD product, but many still ask if CBD oil for dogs has side effects.

Continue reading below to learn about CBD oil and the potential side effects.

What is CBD Oil?

CBD Oil is also known as Cannabidiol. It is a natural compound found in hemp plants. Paws Elite extract CBD from hemp plants using a CO2 extraction. During this extraction, THC is not extracted, and only CBD is. Therefore the CBD oil for pets will not give your pet any psychoactive effect.

When marijuana plants start to flower, they grow trichomes. Trichomes are the glands that have the essential oils that contain THC. This is separated from the plant during the CBD extraction process to prepare the well-balanced CBD oil.

CBD products derived from hemp plant don’t cause any life-threatening side effects because it is non-toxic, non-GMO, vegan friendly and all organic.

How Does CBD Have a Calming and Pain-Relieving Effect?

When Cannabinoids are ingested, they activate the endocannabinoid receptors, which are located in the central and peripheral nervous systems. Once the Endocannabinoid receptors are activated, they help maintain balance in the body, which helps keep it in a normal state. This can help your dog with a calming effect while also reducing any inflammation in their body.

Customer Evidence for Treating Neuropathic Pain and Seizures

No scientific evidence has been completed on CBD, but many customers of Paw’s Elite have provided feedback on their success. CBD is merely a supplement, just like the vitamins we take, but offers the body a little more. It has anti-inflammatory properties that help inflammation, and it also offers benefits such as anti-nausea, appetite stimulation, anti-anxiety, and possible cancer benefits.

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No Life-Threatening Side Effects CBD Oil is Non-Toxic

Dog’s and humans have similar bodies, and most medication prescribed for humans is also prescribed to dogs, but at lower dosages. Just like humans, dogs also have to deal with the side effects of prescribed medicine. CBD products derived from hemp plant don’t cause any life-threatening side effects because it is non-toxic, non-GMO, vegan friendly and all organic. It is a natural supplement that comes from the earth. It is not chemically induced or manufactured, and it provides a list of health benefits that can help manage pain.

CBD oil helps support and maintain a healthy balance in the body by activating the Endocannabinoid system. Large health organizations like World Health Organization and the FDA have recently approved Epidiolex, a drug that contains CBD as an active ingredient. Although no scientific research has been completed, staples in the industry have deemed CBD safe to a certain extent.

Possible Side Effects of CBD in Dogs

The most attractive part about using CBD oil for your dog is very few side effects. Given the few side effects your dog might experience, none of them will hurt or endanger your dog. Not even a high dosage of CBD oil will lead to death.

Learn more about the possible side effects of CBD by visiting: https://pawselite.com/blogs/news/side-effects-cbd-for-dogs

Here are the very few side effects caused by CBD for Dogs
  • Dry Mouth: CBD can decrease the production of Saliva. This will increase your dog’s thirst.
  • Lowered Blood Pressure: This can cause light-headedness, but it is not life-threatening
  • Drowsiness: Due to the calming effect and anti-anxiety support, drowsiness can also occur.

Risks of Using CBD Oil for Dogs

The safety and risks have not been completely researched, but customer feedback and experience have offered the industry huge support. The FDA has not released any information on CBD as medicine and has not recommended the proper dosage chart for CBD. Because of this, CBD dosages should not be recommended. Considering that CBD is a beneficial health supplement, it should be recommended as a serving size. Click this link for CBD oil serving size to read about the recommended serving size for your dog. When you’re giving your dog something new to start with, always start with low amounts to see their reaction. The 3 factors that help understand the CBD serving size are your dog’s age, weight, and breed. Again, nothing life-threatening will happen if you give a high dose.

Paws Elite CBD Oil is crafted with care, and our CBD oil tinctures provide CBD, CBC, CBG, and other beneficial compounds that produce a full spectrum extract full of quality for your cat or dog.

Study evaluates adverse effects of CBD in dogs and cats

Cannabidiol (CBD) use is gaining traction in human and veterinary medicine. Federal legislative changes have opened the door to the distribution of hemp products—as long as they contain less than 0.3% of tetrahydrocannabinol (THC), 1 a psychotropic that’s potentially toxic in animals. 2,3

CBD has been touted for managing anxiety, seizures, cancer, and pain in dogs and cats. However, the FDA discourages its use in these species, 4 as data is scarce on appropriate dosing, long-term effects on serum chemistry, and pharmacokinetics for single or long-term dosing. 5,6

An uncontrolled study recently published in Animals found that while CBD-rich, hemp-based nutraceuticals appear generally safe in a small group of dogs, adverse effects like slower absorption and rapid elimination were observed in cats. 7 Further research is needed to fully understand the safety, metabolism, and overall utility of CBD in dogs and cats.

Evaluating dosing effects

The objective of this trial was to determine the single-dose oral pharmacokinetics of CBD and to provide a preliminary assessment of safety and adverse effects during medium-term administration of a hemp-based product to healthy dogs and cats.

A dose of 2 mg/kg of an oral CBD product (provided by ElleVet) was administered twice daily for 12 weeks to 8 purpose-bred adult beagles with a mean age of 3.2 years old and 8 purpose-bred domestic shorthair cats with a mean age of 4.5 years old. Dogs were administered CBD-infused soft chews and cats, CBD-infused fish oil capsules.

The veterinarian performed physical examinations on all subjects at the start of the study and weekly thereafter. Adverse events observations were made regularly, specifically noting vomiting, loose stool, pain, and distress.

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A complete blood count (CBC) and serum chemistry panel were performed on all subjects prior to the start of the study and every 4 weeks during the trial.

Additionally, a separate pharmacokinetics analysis was performed on 6 of the 8 cats and dogs on the first day of dosing at several time points (dogs: 0, 0.5, 1, 2, 4, 8, 24 hours, cats: 0, 1, 4, 8, 24 hours). CBD was extracted from serum using a combination of protein precipitation and liquid-liquid extraction.

Breaking down the data

Physical exams revealed no abnormalities or weight alterations, and neither inappetence nor behavioral changes were reported in any of the subjects during the 12-week investigation.

However, 53 adverse events, including 44 episodes of soft stool and 6 episodes of vomiting, were reported in dogs. Over 1,100 adverse events occurred in the cats following administration of the CBD-infused fish oil including:

  • Licking (476)
  • Head shaking (339)
  • Pacing (150)
  • Chomping (88)
  • Gagging (29)
  • Salivating/drooling/foaming (16)
  • Vomiting (15)

The acceptance rate of the CBD-infused chews in the dogs was 96.7%.

No significant change in blood chemistry values was reported during the study period. However, mean alkaline phosphatase (ALP) levels rose consistently and sequentially, though staying within the reference range. Cats experienced similar rises in alanine aminotransferase (ALT)— 7 cats remained within the reference range for ALT, but one cat manifested elevated ALT throughout the treatment period. Significant decreases from baseline in blood urea nitrogen (BUN), triglycerides, and creatine kinase were observed in cats.

CBC values remained consistent for the animals throughout the study but for minor but significant drops in mean corpuscle volume (MCV) in the dogs and eosinophils in the cats.

The pharmacokinetics data were reported for 5 dogs— the sixth dog did not consume the entire chew by time 0 and was dropped from this portion of the study. For cats, 2 subjects salivated heavily following administration of the capsules and thus were not among the 6 cats included in the pharmacokinetics evaluation.

The dogs absorbed the CBD more rapidly and thoroughly than the cats, with respective mean maximum concentrations (Cmax) of 301 ng/ml and 43 ng/ml, and mean areas under the curve (AUC) of 1,297 ng-h/ml and 164 ng-h/ml. Mean time to maximal concentration (Tmax) was just 1.4 hours in dogs, versus 2 hours in cats. Dogs metabolized CBD more quickly, with mean elimination half lives (T1/2) of 1 hour for dogs and 1.5 hours for cats. Mean maximal retention time (MRT) in dogs was just 1.4 hours, far shorter than 3.5 hours in cats.

The findings

The glycerol/starch/fiber-based chew used for the dogs is a food bolus considered adequate for optimizing CBD serum concentrations over that previously reported using an oil base. 8 However, the retention and half-life times appeared shortened at 1-2 hours.

This raises questions about the therapeutic efficacy of this chew formulation at the current CBD dose of 2 mg/kg twice daily. An osteoarthritis study using a whole plant extract showed benefits in dogs receiving a 2 mg/kg dose of CBD. 9 Additionally, a canine seizure trial found efficacy at 2.5 mg/kg, producing effective serum concentrations of 200-800 ng/ml. However, delivery methods were not reported.8More work is needed to better understand how food influences CBD absorption and pharmacokinetics.

To date, the absorption of orally-administered CBD in cats has not been investigated. In the current study, maximal serum concentrations in the cats are one-fifth those in dogs. This blunted effect could be attributed to the fish oil base and may suggest that larger doses are necessary for pharmacologic efficacy in cats.

Researchers concluded that hemp-based CBD appears safe in healthy dogs and cats. However, adverse effects were seen in both cats and dogs, including mild clinical signs, modest elevations in liver enzymes, and benign CBC fluctuations. However, the study was uncontrolled and it is unclear whether these effects are attributable to the delivery vehicles versus the CBD.

Additionally, the trial was small, and limited in scope and duration. Further insights might be gained from testing CBD in a broader population and incorporating animals of different ages and maladies.

Current FDA recommendations discourage the use of CBD in pets, and regulatory policy surrounding hemp use is uncertain. More investigation into its safety and efficacy in animals is indicated.

Dr. Joan Capuzzi is a small animal veterinarian and journalist based in the Philadelphia area.