how to use cbd oil for degenerative disc disease

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CBD For Degenerative Disc Disease: What You Should Know

Degenerative disc disease affects nearly 3 million people each year. The disease impacts the discs within the spine. Aging is a significant factor that contributes to this condition as when you normally age, spinal discs wear down, lose their flexibility, and provide less padding. Degeneration of a disc to a particular level makes it difficult to perform its functions effectively as a component of the spinal joint.

All this can cause neck or back pain, numbness, prickling, or different symptoms within the legs or arms. Conservative methods targeted towards curbing pain-related inflammation are often used. However, the healing plant compound CBD has emerged as an adjunct therapy to the mainstream treatment methods.

Table of Contents

Can CBD Help In Treating Degenerative Disc Disease?

The use of CBD oil for degenerative disc disease helps in treating intervertebral disc degeneration. CBD with its safety profile can be a less disputable therapy regime for acute back pain which includes disc degeneration in the following ways.

New research investigated by a group of researchers from the University of Sao Paulo, Brazil explored the results of CBD on DDD. As they built a degenerative disc disease (DDD) model in mice they gave different doses of CBD which was received by an experimental group. The researchers applied MRI to examine the consequences of CBD after 2 and 15 days of its administration. When they viewed images and noticed the injury regions at a cellular level through histological evaluation. They discovered that CBD can be highly effective in decreasing the impairment of intervertebral discs.

The phytocannabinoid showed remarkable effects on the outer circular part of the intervertebral disc known as annulus fibrosus which safely links the spinal vertebral on the top and under the disc. This strong wrapping safeguards the soft substance situated in the middle of the disc.

Although the fluctuations in the soft center or nucleus pulposus were found to be negligible which together with the annulus fibrosus constitute the intervertebral disc.

CBD Interacts With ECS And Elevates Anandamide Levels

The findings on cannabinoids have fueled research on the medicinal benefits of these plant molecules on the human system. The vast signaling network that makes our physiological system work in a regular balanced state is the endocannabinoid system. This system helps to maintain a state of balance or homeostasis and exhibits modulatory effects on the immune system, endocrine system, central & peripheral nervous system, and metabolism.

CBD indirectly activates the receptors of the endocannabinoid system and raises the anandamide levels. This occurs due to the cannabinoid inhibiting the enzyme FAAH. It plays a major role in the breakdown of the endocannabinoid anandamide. This property makes CBD a reuptake inhibitor of anandamide.

CBD Can Mitigate All Types Of Pain

CBD oil can work on all types of pain -neuropathic, chronic or nociceptive. To the question, does CBD help with back pain, well the answer is yes! CBD can bind to the TRPV1 receptor which is the site regulating pain signals. Moreover, CBD can be effective in pain management as it can exert its analgesic effects through different interactions and regulation of the inflammatory, endocannabinoid, and pain perceiving or nociceptive systems.

CBD also inhibits the degradation of the neurotransmitter and endocannabinoid anandamide which helps it to remain in the body for a prolonged duration. Anandamide also known as Bliss Molecule helps in alleviating the symptoms of disc disease. Pain manifests in degenerative disc disease while bending or turning the spine as well as while picking heavy objects.

According to a 2018 study, the potential of CBD in reducing nerve-induced and inflammatory pain supports its role as a mainstream pain management option. Evidence has indicated the role of CBD as a safe addiction treatment for opioid abuse and chronic pain-alleviating therapy.

A Potent Anti-Inflammatory Agent

Disc degeneration can lead to inflammation in adjoining structures as it is the way of defensive response by the body towards damaged tissue, infections, and lesions. Muscle inflammation can produce spasms or numbness in the back or neck.

Cytokines are the signaling proteins released or generated during any injury, damage, or infection by the immune cells. This signaling protein leads to inflammation. Researchers hold that cannabinoids can regulate inflammation by modulating cytokine production within immune cells.

Research published in 2018 in the Journal of Pharmacology and Experimental Therapeutics indicated the anti-inflammatory properties of cannabinoids. CBD hampers the production of cytokines by modulating the reactions of the immune system.

The production of MCP-2, a kind of leukocyte is minimized by the simulation of CB2 receptors. CBD helps in reducing the production of different proinflammatory agents – interleukin (IL) -6 and IL – 8 with no cytotoxic effect.

Studies have hinted at the capacity of CBD to be a viable pharmacological option to mitigate inflammation and pain.

CBD Can Be Beneficial In Herniated DIsc

In herniated discs, the rubbery cushions situated within the spinal bones called vertebrae to get degeneration. Your vertebrae are buttressed by small discs composed of jelly-type substances and help in the mobility and twisting of your spine. If these discs move out inflammation and pain can result.

CBD oil for bulging disc pain can be effective in reducing the intensity of the pain and numbness. The analgesic and anti-inflammatory nature of CBD can be helpful in pain management and inflammation. On the issue of can CBD oil help spinal stenosis, the results show a positive outcome. CBD also helps in alleviating multiple symptoms associated with spinal stenosis namely nerve pain, anxiety, inflammation, and inadequate sleep.

Can Manage Psychological Signs Of DDD

Back pain therapy involves multiple approaches by way of specialized exercises, strength workouts, and physical therapy. A mental state which impacts your pain perception and capacity to manage the medical condition is a major factor that helps in radiating back pain. DDD can influence a patient psychologically by raising anxiety levels, depression, and thinking about negative situations.

Alongside addressing the physical issues of DDD, CBD can be helpful in alleviating psychological aspects too.

According to research, CBD alters the manner of brain response towards serotonin. As stated earlier, CBD also inhibits the breakdown of the happiness neurotransmitter anandamide which boosts mood fluctuations and pain perception.

Looking For The Best CBD oils For DDD

While purchasing CBD oil, consider the following points:

  • Look for products sourced from organic hemp plants.
  • Look for brands using supercritical CO2 extraction techniques
  • Products should be third-party tested.

This helps you to know that your bottle holds a clean product, is contaminant-free, and remains within the permissible THC levels.

Buying CBD oils and tinctures from premium online manufacturing and retailing brand Cibadol ensures product purity and efficacy. Their in-house cGMP manufacturing unit uses state-of-the-art supercritical CO2 extraction techniques for pure CBD production.

You can choose from the full-spectrum products with their health-boosting molecules resulting from the synergistic effects of cannabinoids, terpenes, chlorophyll, flavonoids, and beneficial plant compounds. With a vast assortment of broad-spectrum CBD products, THC-free products, CBD isolates, gummies, Softgels, and a wide range of topical and drink tablets besides others.

Final Thoughts On CBD For Degenerative Disc Disease

The medicinal benefits of CBD can confer positive effects on managing the symptoms of degenerative disc disease. Usage of CBD for herniated disc and spinal stenosis produces mitigating effects by relieving inflammation, acute back, and nerve pain, as well as compressed nerves.

CBD packed with neuroprotective, anti-inflammatory, anxiolytic, and analgesic properties make a viable solution for preventing further neurodegeneration which is best suited for treating sciatica and herniated disc symptoms.

Can CBD Treat Degenerative Disc Disease?

Degenerative disc disease is a large contributor to back pain, a cause of chronic pain for many. CBD has been shown to attenuate this degeneration within animal models, and could be a possible treatment in the future.

CBD continues to gain recognition as a natural medicine as ever more scientific research and anecdotal accounts come rolling in. Otherwise known as cannabidiol, CBD is a non-psychotropic cannabinoid synthesised within the flowers of the cannabis plant. As one of the most researched cannabinoids, CBD has so far displayed anti-inflammatory, analgesic, antioxidant, neuroprotective, anti-tumour, and anticonvulsant properties.


CBD also shows potential in the treatment of various musculoskeletal pathologies. The compound interacts with the endocannabinoid system, a regulatory system within the human body comprised of various receptor types, including CB1 and CB2 receptors. CBD also interacts with GPR55, a cannabinoid receptor associated with increased bone mass in animal studies.


When it comes to preserving the discs of the spine, here too CBD displays promise. Research is ongoing regarding CBD’s potential as a future treatment for degenerative disc disease. Although current research has been performed using animal models, further human research could mark a breakthrough in this arena. Intervertebral disc degeneration is reported to be the main contributor to low back pain, a condition that affects large portions of the world’s population.

Recent research suggests that CBD has a protective effect over intervertebral discs in vivo. However, before we dig into the data, let’s take a look at exactly what discs are and how they begin to degenerate.


An intervertebral disc sits between two spinal vertebrae within the vertebral column and contributes to the formation of a fibrocartilaginous joint. These discs have multiple functions, including shock absorption for the spine, movement, and stability of the spine.

Each disc features an outer ring, or annulus fibrosus, composed of several layers of fibrocartilage made up of different types of collagen. Within this ring exists a gel-like centre containing loose fibres called the nucleus pulposus. It’s this gel-like substance that allows discs to absorb physical shock during movement and activity.

Many people will have heard of the so-called phenomenon of a “slipped disc”. What this actually means is that the gel-like fluid of the nucleus pulposus been forced against the annulus fibrosus to the point of protrusion or prolapse. This can be caused by physical trauma during activity or by chronic deterioration in the form of poor posture. The nucleus pulposus can herniate in lateral and posterior directions and cause symptoms such as numbness, pain, and loss of sensation due to pressing on nerves.


Intervertebral disc disease is characterised by the gradual breakdown of one or more discs within the spine. Disc degeneration is a natural part of ageing, with around 25% of individuals displaying evidence of degeneration before the age of 40. During this process, the nucleus pulposus begins to lose some of its water content and the annulus fibrosus becomes more prone to tearing, resulting in possible herniation.

Degeneration and subsequent herniation can lead to spinal nerve compression, which can result in pain, weakness, and numbness in the extremities. As degeneration continues, bone spurs can form at the edge of individual vertebra, causing further compression of nerves, and possibly causing issues with walking and bladder/bowel control.


CBD has already shown early efficacy as a potential musculoskeletal medicine, and more evidence is mounting. A 2014 study published within the journal PLoS One investigated the protective effect of CBD on lesion-induced intervertebral disc degeneration within rats.

Researchers first induced damage to intervertebral discs via needle puncture to create a lesion. The rats were then divided into three sub-groups, with 6–7 animals in each group. Each group was then administered a different dose of CBD via injection: 30, 60, and 120 nmol.

After administration, the researches used MRI (magnetic resonance imaging) and microscope analysis to examine the induced injuries. The results of the analysis revealed no improvements within the 30 and 60 nmol groups. However, improvement in lesion damage was seen in the 120 nmol group in both MRI and microscope imaging up to 15 days afterwards.

These results led the authors to state that the study revealed the anti-degenerative effects of CBD injection at 120 nmol. Although more research is required in this domain, such results indicate the future use of CBD for disc degeneration treatment.


Inflammation plays a large role within the process of degenerative disc disease. Although specific studies need to be performed to find a correlation, CBD has been shown to exert anti-inflammatory effects by interfacing with cannabinoid and adenosine receptors.

Pain also plays a large role in degenerative disc disease, particularly neuropathic pain that stems from compression of nerves due to herniation. CBD may help to relieve this side effect as there is some evidence to suggest cannabinoids are effective in reducing neuropathic pain.

Finally, CBD may help to tackle some of the psychological symptoms associated with degenerative disc disease. The compound displays anxiolytic and antidepressant-like effects that can help boost the quality of life of sufferers.