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What is CBD? The 'miracle' cannabis compound that doesn't get you high

In early May, a federal court declined to protect cannabidiol (CBD), a chemical produced by the cannabis plant, from federal law enforcement, despite widespread belief in its medical value.

The ruling was contrary to existing evidence, which suggests the chemical is safe and could have multiple important uses as medicine. Many cannabis advocates consider it a miracle medicine, capable of relieving conditions as disparate as depression, arthritis and diabetes.

The perception of its widespread medical benefits have made the chemical a rallying cry for legalization advocates.

The first thing to know about CBD is that it is not psychoactive; it doesn’t get people high. The primary psychoactive ingredient in marijuana is tetrahydrocannabinol (THC). But THC is only one of the scores of chemicals – known as cannabinoids – produced by the cannabis plant.

So far, CBD is the most promising compound from both a marketing and a medical perspective. Many users believe it helps them relax, despite it not being psychoactive, and some believe regular doses help stave off Alzheimer’s and heart disease.

While studies have shown CBD to have anti-inflammatory, anti-pain and anti-psychotic properties, it has seen only minimal testing in human clinical trials, where scientists determine what a drug does, how much patients should take, its side effects and so on.

Despite the government ruling, CBD is widely available over the counter in dispensaries in states where marijuana is legal.

CBD first came to public attention in a 2013 CNN documentary called Weed. The piece, reported by Dr Sanjay Gupta, featured a little girl in Colorado named Charlotte, who had a rare life-threatening form of epilepsy called Dravet syndrome.

At age five, Charlotte suffered 300 grand mal seizures a week, and was constantly on the brink of a medical emergency. Through online research, Charlotte’s desperate parents heard of treating Dravet with CBD. It was controversial to pursue medical marijuana for such a young patient, but when they gave Charlotte oil extracted from high-CBD cannabis, her seizures stopped almost completely. In honor of her progress, high-CBD cannabis is sometimes known as Charlotte’s Web.

CBD has been sought for its healing properties. Illustration: George Wylesol

After Charlotte’s story got out, hundreds of families relocated to Colorado where they could procure CBD for their children, though not all experienced such life-changing results. Instead of moving, other families obtained CBD oil through the illegal distribution networks.

In late June, the US Food and Drug Administration could approve the Epidiolex, a pharmaceuticalized form of CBD for several severe pediatric seizure disorders. According to data recently published in the New England Journal of Medicine, the drug can reduce seizures by more than 40%. If Epidiolex wins approval it would be the first time the agency approves a drug derived from the marijuana plant. (The FDA has approved synthetic THC to treat chemotherapy-related nausea.)

Epidiolex was developed by the London-based GW Pharmaceuticals, which grows cannabis on tightly controlled farms in the UK. It embarked on the Epidiolex project in 2013, as anecdotes of CBD’s value as an epilepsy drug began emerging from the US.

While parents treating their children with CBD had to proceed based on trial and error, like a folk medicine, they also had to wonder whether dispensary purchased CBD was professionally manufactured and contained what the package said it did. GW brought a scientific understanding and pharmaceutical grade manufacturing to this promising compound.

Fortunately, like THC, CBD appears to be well tolerated; as far as I can tell, there are no recorded incidents of fatal CBD overdoses.

Top 5 Benefits of Cannabis for Diabetes

The prevalence of diabetes around the world continues to rise, and the world is in dire need of a viable solution to this problem. Scientists have been busy at work researching the effects cannabis has on diabetes prevention and obesity prevention, which is one of the biggest causes of diabetes. Cannabis may have multiple benefits for diabetes, five of which we cover in this article.

Diabetes is the term for a group of related metabolic disorders characterized by prolonged high blood glucose levels. Diabetes affects over 420 million people worldwide (2014), resulting in millions of deaths per year–and its prevalence is rising. Substantial evidence indicates that cannabis may help to prevent and treat the disease.

There are 2 main types of diabetes:

  1. Type 1 occurs when immune system attacks and destroys the insulin-producing beta cells of the pancreas, and insulin injections are needed. The cause is unknown, and it can occur at any age.
  2. Type 2, when the body doesn’t use insulin effectively. Type 2 diabetes is more common than type 1. There are several known causes of type 2 diabetes, of which genetics and lifestyle are the most important ones. Type 2 diabetes mainly occurs in adults, but is increasingly diagnosed in children.

1. Cannabis may be preventative for diabetes

Diabetes is associated with high levels of fasting insulin and insulin resistance, as well as low levels of high-density lipoprotein cholesterol (HDL-C). In 2013, the results of a five-year study into the effects of cannabis on fasting insulin and insulin resistance were published in the American Journal of Medicine. Of the 4,657 respondents, 2,554 had used cannabis in their lifetime (579 were current users and 1,975 were past users) and 2,103 had never used the drug.

The researchers found that current users of cannabis had 16% lower fasting insulin levels than respondents who had never used cannabis, as well as having 17% lower levels of insulin resistance and higher levels of HDL-C. Respondents who had used cannabis in their lifetime but were not current users showed similar but less pronounced associations, indicating that the protective effect of cannabis fades with time.

The researchers also ran analyses on the data that excluded individuals diagnosed with diabetes. Even after excluding diabetics, current cannabis users were found to exhibit reduced fasting insulin and insulin resistance levels, indicating that cannabis can help prevent the occurrence of diabetes as well as controlling symptoms in diagnosed cases.

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2. Cannabis lowers insulin resistance

Insulin resistance (IR) is a condition that causes cells to reject the normal mechanism of insulin, a hormone that is produced by the pancreas and is fundamental to the regulation of glucose metabolism. IR is associated with type 2 diabetes. In type 1 diabetes, the body is unable to produce insulin, while in type 2, insulin production is unaffected, but the cells are unable to process it.

When cells become insulin-resistant, they are unable to absorb the glucose needed to supply them with energy, and the unused glucose builds up in the bloodstream, leading to hyperglycemia.

The authors of the 2013 study found that current users of cannabis had a mean IR of 1.8, compared to 2.2 for past users and 2.5 for those that had never used cannabis. Current cannabis users were also found to have lower levels of blood glucose compared to past users and non-users. Current users had mean blood glucose levels of 99.7 mg/dL, compared with 100.6 mg/dL for past users and 103.5 mg/dL for non-users. However, the precise mechanism via which cannabinoids exert their effects on IR has thus far not been determined.

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3. Cannabis helps to prevent obesity

Obesity, high body mass index (BMI) and large waist circumference are all linked to type 2 diabetes risk. Various studies have been conducted on the relationship between cannabis use and BMI, with conflicting results. A 2005 study on young adults found that cannabis use was not associated with higher BMI levels, whereas two large national surveys found slightly lower BMI and decreased levels of obesity in cannabis users despite higher-than-average daily consumption of calories. The 2013 study discussed earlier found that current cannabis use was associated with smaller waist circumferences than in past or non-users.

While the mechanism underlying the complex relationship between the endocannabinoid system, obesity and diabetes has not been fully established, a 2012 study demonstrated that obese rats lost significant weight and experienced an increase in pancreas weight after exposure to organic cannabis extract.

The increase in the weight of the pancreas indicates that the beta cells of the pancreas (which are responsible for the production of insulin) are protected by the presence of cannabinoids. In type 1 diabetes, the beta cells are destroyed by an autoimmune response, so providing protection to them may help to control the disease.

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4. Cannabis may treat diabetes-induced neuropathy

People with diabetes often experience nerve disorders as a result of their disease. Nerve damage often affects the peripheries such as the hands and feet, but may occur in any organ or region of the body. The damage may be symptomless, but in many cases, pain, tingling and numbness accompany the disorder. As with many forms of nerve pain, diabetic neuropathy can be hard to treat with conventional analgesics. However, there is evidence to indicate that cannabis may have a role to play here too.

A study published in 2009 investigated the antinociceptive (pain-reducing) effects of cannabidiol extract in cases of diabetes-induced neuropathy in rats. The authors found that repeated administration of CBD extract “significantly relieved” mechanical allodynia (painful response to non-painful stimuli) and restored normal perception of pain without inducing hyperglycemia.

The treatment was also found to protect the liver against oxidative stress (which is believed to be a major contributing factor to developing neuropathy) and increase levels of nerve growth factor to normal levels.

However, studies on humans have thus far yielded less positive results. Also in 2009, a randomized controlled trial investigated the ability of GW Pharmaceuticals’ Sativex spray to ameliorate the symptoms of diabetic peripheral neuropathy. 30 subjects were administered with either Sativex or placebo. Pain scores improved significantly across the board, but the effect of Sativex was not found to be significantly greater than that of the placebo.

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5. Cannabis may treat diabetic retinopathy

Up to 80% of diabetes patients that have had the disease for over a decade acquire a complication known as diabetic retinopathy (DRP), in which the cells of the retina are progressively damaged. This condition is responsible for approximately 5% of new cases of blindness each year in the USA.

DRP is associated with glucose-induced breakdown of the outer blood-retinal barrier, a network of tightly-packed cells that prevent unwanted substances in the blood from entering retinal tissue. This breakdown causes neural tissue to be exposed to neurotoxins, as well as increasing the chance of bleeding within the retina.

It is thought that the pro-inflammatory immune response and oxidative stress processes have a key role to play in the breakdown of retinal cells. There is evidence that cannabidiol, with its known ability to combat both oxidative stress and inflammation, may be useful in treating the disorder.

In a 2006 study published in the American Journal of Pathology, diabetic rats were administered with CBD and tested to determine the rate of retinal cell death. It was shown that treatment with CBD significantly reduced oxidative stress and neurotoxicity and protected against retinal cell death and the breakdown of the bood-retinal barrier. This included reducing levels of tumour-necrosis factor-alpha (TNFα), a substance that is known to be involved in the inflammatory response.

Although mainstream and stereotypical thought about cannabis users would suggest that cannabis may have a negative effect on BMI, the waistline and diabetes, scientific evidence suggests otherwise. Overall, cannabis users are associated with lower risk of diabetes and lower risk of obesity, one of the leading causes of type 2 diabetes.


119 thoughts on “Top 5 Benefits of Cannabis for Diabetes”

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Overhere as good as reversed type 2 diabetes (at least I hope so, I may try it for 2 months to live without the 1 tablet metformin I used for 11 months

The last time when I smoked some pot (tha was 1.5 weeks ago), I ended up as good as hypoglycemic … (Okay, I have to say it was a strong one with strong tobacco) … It was no fun …

Diabetic for 15.5 years, cannabis user for 9 years. My original intent with cannabis was honestly to feel what “being high” was all about. I researched it for quite some time and in 2007-2008, I became curious with no real intent yet to seek it out, but I was intrigued. After fate finally brought me to the plant, I’ve never looked back. Over the years, I’ve used it to supplement my exercise regimen and even used it prior to running. For me personally, there has been tremendous therapeutic value with rest, recovery, and amazing sleep. I regulate my sugars well, 11-13 units of Lantus nightly, and most days I only use 15 units of fast acting insulin between my 3 meal times. I consistently run 20-35 mpw depending on the season or what races I might be peaking for. I don’t carb count, as that’s all too black and white for me. I get a lot of fat in my diet, and keep simple sugars to a minimum. The synergistic potential of the Endocannabinoid and Endocrine systems aren’t mainstream, yet, but we’re getting there. Find a reasonable dose for yourself and your lifestyle. Understand how cannabis works in your body, stay hydrated, and watch your life change for the better.

I believe and always have that marijuana had something to do with my onset diabetes when I got married for the second time my husband refused to let me smoke marijuana and then I turned into a full-blown diabetic type two I’m now taking CBD oil and it seems to be helping lower my blood sugar and helping me get off the medication.

Thanks for the info on the study of CBD oil, I am 66 years and type2 diabetic, have used the oil for a month and A1C went from 8.7 down to 6.9 , I am happy for the results but haven’t told my doctor yet, I will at next visit in December.

I am suffering from type 1 diabetes for over 15 years now. How do I apply the cannabis if I can’t access the oil.

Thank you for your comment. I’m afraid I don’t completely understand what you are asking – do you mean that you do have cannabis but you can’t access the oil? Or how to get hold of other cannabis products? I’m afraid we cannot give general advice on obtaining cannabis, especially without knowing where someone lives, due to legal restrictions. If you do have cannabis, the most widely recommended medicinal method of ingesting is vaporising. However, as with any new medicine (or food supplement, even), you should consult your medical practitioner first. This article, written specifically for medical professionals, may be helpful when you do so.

With best wishes,

I was feeling tired all the time and constantly thirsty. I had a medical today and I have too much sugar in my urine. Im having a blood test in 3 days. My doctor suspects I may have diabetes. I’m 55 and worried. I do have access to cannabis oil. I am going to start taking it, Ive been advised to only have a tiny bit at first and eventually work up to a grain of rice size a day.
I found this page extremely interesting and will keep reading all the posts.
Thank you.
Darcy. xx

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I just started using CBD oil yesterday for bad pain in my leg and for Diabetes. How long before it starts working and how often should you take it a day.

Thank you for your comment. We are sorry to hear about your situation. Unfortunately, as Sensi Seeds is not a medical practice, we are not able to provide any advice relating to medical situations other than to consult your doctor or other licensed medical professional. This article, written specifically for healthcare providers who may not be aware of the many properties of cannabis, may be useful to you in talking with your doctor. You could also try to contact local medicinal cannabis support groups, if you have not already done so. In the UK, there is the United Patients Alliance (you can find them on Facebook) and in the US and EU there are many branches of NORML (google NORML followed by your area name). We hope this is helpful.

With best wishes,

My mother has many different ailments including fibromyalgia, arthritis, constant hip pain from a failed hip replacement, digestive issues and some other problems associated with type 2 diabetes. She has found the cbd product to be the only thing that really works for her. – Jeannie

So glad to hear that the CBD oil is working for your mom!

Hi I have type 2 diabetes. I bought a bottle with a dropper that is 100 mg. Suggested amount is 12 drops per day. How much is good to start with??

I’m a type 2 diabetic. I’ve been hearing about the cbd oil. How do you take it? Also can you drink the cbd water and get results as well?

Here you can find information about our CBD products. This is the CBD Oil, which includes information about how to take it. I’m not sure what you mean by ‘cbd water’; cannabinoids are not water soluble in this form, and the oil itself is quite thick, so I do not think that mixing the oil with water would work very well.

With best wishes,

I’m also interested. What strain helped the most? Or would a hybrid be best.Thanks, Renee

Thank you for your comment. Unfortunately, as Sensi Seeds is not a medical practice, we are not able to provide any advice relating to medical situations other than to consult your doctor or other licensed medical professional. This article, written specifically for healthcare providers who may not be aware of the many properties of cannabis, may be useful to you in talking with your doctor. You could also try to contact local medicinal cannabis support groups, if you have not already done so. In the UK, there is the United Patients Alliance (you can find them on Facebook) and in the US and EU there are many branches of NORML (google NORML followed by your area name). We hope this is helpful.

With best wishes,

Hi, I am a type 1 diabetic and my boyfriend smokes. He was telling me about how marijuana could help my diabetes. How can it help and does it help more by smoking or what?

Thank you for your comment. We are sorry to hear about your situation. Unfortunately, as Sensi Seeds is not a medical practice, we are not able to provide any advice relating to medical situations other than to consult your doctor or other licensed medical professional. This article, written specifically for healthcare providers who may not be aware of the many properties of cannabis, may be useful to you in talking with your doctor. You could also try to contact local medicinal cannabis support groups, if you have not already done so. In the UK, there is the United Patients Alliance (you can find them on Facebook) and in the US and EU there are many branches of NORML (google NORML followed by your area name). We hope this is helpful.

With best wishes,

i suffer with a sliped disc in my lower back and i am type 2 i smoke one small spliff for pain in my back at nite to sleep my h1 c is now 48 from 72 in about a year i take 1 metaformin a day eat like i used to and i have lost 3 stone in year i think its worked for me but look for a good weed type like a high cbd and low thc i was 23 stone before try b52 or bigbud weed plant or eat raw hemp leaves in a salad its finding the one that works for you

Cannabis isn’t something that can cure diabetes but it may help to control it. Here is what it says on Rick Simpson’s site.

Diabetics should also be aware that they will usually find that their need for insulin will be reduced and it may even decrease to the point, where they will no longer require its use at all and the same goes for most other pharmaceuticals as well. Diabetics are diagnosed with type1 or type 2 diabetes and no matter what type you suffer from, it is still beneficial to use this oil because not only will it decrease your need for insulin, it will also protect your body from all the other harm this disease can cause.

I was very interested in the comments made. But not getting any definate answers I am in my 80s and have just been diagnosed with type 2 diabetes so I thought I would try smoking Cannabis with the hope it would help but have not helped can anyone say how long it will take before I feel any benefit is there anyone that can give an answer to say how much to smoke and how long before you feel any benefit perhaps this is a lot to ask as I am DESPERATE as I am finding it difficult to walk at the moment because of the feelings in my feet and legs people says it is your age but I knew it isn’t that so thanks for the comments B xx

This is for can try cbd oil or tincture. Make sure the cbc/the ratio is 10 to 1 or 20 to 1. I’m dibetic type 2 and started to take the tincture 20/1 sublingual. Pain on my feet decreased and feel less tingling on my hands after a week. Its great medicine. Continue taking your meds for diabetes. Good luck!

Barbie i believe the best method would be to use the CBD oil . place drops under ur tongue and hold it for a moment and then swallow. im not an expert on any of this but when cannabis is smoked it destroys some if the different chemicals that are helpful.

I used cannabis medicinally in the 1970s-80s to treat insomnia and depression due to PTSD (I’m a childhood abuse survivor). I quit using it when I got pregnant and never went back to using it because I was raising a child. However, about 5 years after I quit using cannabis, I developed Type II diabetes. I was pre-diabetic for about 16 years (I’m mostly a vegetarian who eats fish), then my A1C gradually moved up above 6.0-6.1. By the time I retired, my A1C had risen to 6.5. Then, I moved to a state where medical cannabis is legal and began using it again. That was 1.8 years ago …. and just 7 months ago, I found out my A1C has dropped down to 5.5. My doctor (G.P.) is now considering taking me off of metformin!! Although I never was an insulin-dependent diabetic, I was “pre-diabetic” or “diabetic” for 20+ years. I thank medical cannabis for getting rid of my diabetes!

Hi, how did you use the cannabis? Did you smoke it or use oils?

I’m in the same situation as far as A1C numbers. My doctor and I made a deal that if I can lower my numbers for diabetes, blood pressure and cholesterol by May 1st (four weeks away), she won’t put me on meds. I’m curious. How are you using cannabis to lower your numbers? Smoking, oils, etc?

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Did you take Cbc oils and what kind and How much?

Did you use oil? I’m thinking of trying Cbd oil from Amazon .

I have heard that you need to be careful of buying CBD oil online because many have high levels of metals. Just be careful

My father has had Diabetes for over 10 years now and we have been looking for an alternative for his neuropathy and other issues he has gained over the years from being a diabetic.
Now fortunately we’ve have just recently come across CBD oil. You take a few drops a couple times a day under your tongue and it helps with multiple issues.
So far so good.
I pray it continues to help him

What brand do you use? Is it pure with no thc? And where do you get it? Thanks

I have diabetes and my A1C is 12. And hyprertension. how would I know the right cbd oil for me . And i drink metformin.

Is it safe to use cannabis oil when trying to get pregnant or already pregnant

There is not enough evidence to answer ‘yes’ to this question; as with all drugs, and even food supplements, new diets and exercise, definitely consult a qualified medical practitioner before starting them, especially if you are pregnant or trying to become pregnant.

With best wishes,

I need cure but it is illegal where I stay

Try cannabis oil

I have diabetes and it is illegal in my state but you suggested cannabis oil, where do i get it and how do I use it. Does this also help with chronic pain? if so, how long does it take to feel the effects of it. I am new to all of this so help . thanks

Hi I was diagnosed with Diabetes 6yrs ago and would like to find out how this works and how to administer it.

Hi , i was diagnosed with type2 diabetese last year , i take insuline 3 times a day plus 2 metphormin a day plus a bunch of pills for blood pressure , some for kidneys , i had diabetic foot it got infected with the flesh eating bacteria , they had to operate almost lost my foot , and to make it worst had a small cyst on my bach that turned bad and had to get operated again they took a 12 cm piece out of my back , and an other symptom i have now is in my left eye loosing vision a bit and started to get neuropathy in my left hand , wondering if cannabis oils would cure me or is it to late , never took any before , am new to this

I am a 3 year veteran of type 2 diabetes. I cycle most every day. At the moment I am cycling about 160+ miles / week. I still have neuropathy but my sugars are well controlled with this amount of exercise. You have to exercise or you’ll have feet and hands chopped off. Even the patron saint of diabetics had one of her hands removed. So I strongly recommend exercising each and every day.

I’m excited to see these awesome studies. I’m a believer in natural healing plant medicine and I’m currently using CBD Hemp oil for my severe asthma and arthritis. It has totally changed my health and I have my life back.
I’m open to share with anyone seeking more info.

Looking into cbd oil for type 2 diabetes and was wondering what u think

I’ve only been on CBD Oil for a month. Almost immediately, excruciating pain from osteoarthritis and bone spurs in my leg ceased. I was terrified that I would have to get a walker because I could barely walk because of the pain!! CBD Oil has incredible anti-anxiety properties and halted my nervousness, fearful thoughts, anxiety and panic from severe PTSD. A beautiful peacefulness, relaxation and solitude comes over you after taking a dose, yet there is no ‘high’ as there is with THC. I suspect this CBD Oil will also help with my Type 2 Diabetes. In short, it has changed my life for the better and I don’t hesitate to recommend this oil to anyone suffering from pain or anxiety. CBD Oil has many more properties, including anti-inflammatory, anti-psychotic, pain-reducing, anti-oxidant, and improves REM sleep. It stimulates alertness, reduces daytime sleepiness, and improves depression (works on Serotonin).

What dose are you taking?

Guy ,you just need to reserch Rick Simpson oil !!he has many videos and has done all the hard work and reserch !! weed oil works .

Angel, this article should make it more clear that most of the research being done on canabis and diabetes relates to Type II Diabetes. However I am sure that cannabis will help with the neuropathic effects of Type I if not the Insulin problem. Fingers crossed that researchers will be able to help all Diabetes sufferers in the near future.

As a type one diabetic for 35 years, insulin dependent, I find some of the info here just wrong. My body produces zero insulin, Cannabis will not help me produce insulin, my pancreas islets of Langerhans are all destroyed by my own immune system. Cannabis is useful for many diabetics, as alcohol is deadly, and Cannabis of itself is not as it is zero calories.

Angel: using medicinal cannabis can help heal your type-1 diabetes, which is PROVEN scientifically: [article title] Cannabinoids Induce Pancreatic β-Cell Death by Directly Inhibiting Insulin Receptor Activation

That is the scientifically proven mechanism about how medicinal cannabis helps cure the most common type of diabetes.

Great work,keep it up.

Just smoke the weed IDK what y’all talking form ? Go out get some weed in smoke a bowl I’m a type diabetic for 15years use to smoke when was younger had no problems quite when I was 19 now I’m 30 n have retnopthy started smoking it again haven’t loss anymore sight

I’m 18, and I just got diagnosed with diabetes but my doctor isn’t the best. He didn’t explain nothing to me but it does run in my family. My brother told me about cannabis can help diabetes. What kind of form of cannabis helps the most? Oil?

You want to make oil out of high grade bud if possible. You can’t get enough cannibinoids from smoking it. It’s fine for pain but to get the benefits and treat symptoms you need to make oil.

How is the oil applied? I am diabetic and really need help.

I have Diabetes and suffer from Neropathy in my legs,feet, and hands. The pain is unbearable and makes it hard to walk and do anything. I live in Texas and am a disabled veteran. Does Texas have opportunity to try marijuana therapies to help with the Chronic Pain. I take pills now but geez this is old. Also are they any Physicians that can give me advice on this type of therapy? I am to the point of needing a pwr wheelchair to get around but fear when I do this I will lose all muscles that are left in my legs now. Seeking help and help with this. Thanks !!

Hey Gordon, get the book Healing Diabetes: The Gerson Way. I’m not trying to sell you this book in any way. I started feeling really sick and sore in my legs from drinking and eating bad and I think I’m diabetic now as a result. I’m gonna get this book my self. Check out the “Gerson Miracle” movie on youtube. Your eye will be open to the truth be pharma doesn’t want you to see. By the way, the book states that you can be free syptoms in less then two weeks. Your case may take longer but you got nothing to loose. It all seems logical to me, so I’m gonna try it my self.

I think the best remedy is to do intermittent fasting which helped me to cure diabetes completely and now am diabetes free. I also used Wheatgrass and omega 3 as supplement during fasting. Please try this which is very effective. For more send me a mail, I can help