hemp oil vs cbd oil for epilepsy

Synthetic Version of CBD Treats Seizures in Rats

A synthetic, non-intoxicating analogue of cannabidiol (CBD) is effective in treating seizures in rats, according to research by chemists at the University of California, Davis. The synthetic CBD alternative is easier to purify than a plant extract, eliminates the need to use agricultural land for hemp cultivation, and could avoid legal complications with cannabis-related products. The work was recently published in the journal Scientific Reports.

“It’s a much safer drug than CBD, with no abuse potential and doesn’t require the cultivation of hemp,” said Mark Mascal, professor in the UC Davis Department of Chemistry. Mascal’s laboratory at UC Davis carried out the work in collaboration with researchers at the University of Reading, U.K.

Products containing CBD have recently become popular for their supposed health effects and because the compound does not cause a high. CBD is also being investigated as a pharmaceutical compound for conditions including anxiety, epilepsy, glaucoma and arthritis. But because it comes from extracts of cannabis or hemp plants, CBD poses legal problems in some states and under federal law. It is also possible to chemically convert CBD to tetrahydrocannabinol (THC), the intoxicating compound in marijuana.

8,9-Dihydrocannabidiol (H2CBD) is a synthetic molecule with a similar structure to CBD. Mascal’s laboratory developed a simple method to inexpensively synthesize H2CBD from commercially available chemicals. “Unlike CBD, there is no way to convert H2CBD to intoxicating THC,” he said.

One important medical use of cannabis and CBD is in treatment of epilepsy. The U.S. Food and Drug Administration has approved an extract of herbal CBD for treating some seizure conditions and there is also strong evidence from animal studies.

The researchers tested synthetic H2CBD against herbal CBD in rats with induced seizures. H2CBD and CBD were found to be equally effective for the reduction of both the frequency and severity of seizures.

Mascal is working with colleagues at the UC Davis School of Medicine to carry out more studies in animals with a goal of moving into clinical trials soon. UC Davis has applied for a provisional patent on antiseizure use of H2CBD and its analogues, and Mascal has founded a company, Syncanica, to continue development.

Additional authors on the paper are Nema Hafezi and Deping Wang at UC Davis, and Yuhan Hu, Gessica Serra, Mark Dallas and Jeremy Spencer at the University of Reading.

What’s The Difference Between THC Oil, Hemp Oil, CBD Oil and Hash Oil


First, hemp and cannabis are not different plants per se. They are breeds or varieties of the same species: cannabis sativa. Nevertheless, the two varieties have several significant differences that range from how they grow and look to their uses and the chemical compounds in their extractions.
For instance, while hemp grows up to fifteen feet tall with long, massive stalks, cannabis grows outward with more leaves and buds and rarely exceeds five feet in height. The industrial hemp plants also seem to grow comfortably closely packed together while each cannabis plant requires some space to grow.

But the most significant difference, especially in regard to the oils, is in the chemical compounds they contain, which are also referred to as cannabinoids. Cannabis-derived oils are increasingly popular, and their uses and properties differ depending on what part of the plant they come from and how they are created. Here is a quick run-through of the differences in these oils and their uses.

THC Oil/Cannabis oil

Cannabis oil is made using the bud of the marijuana plant plus some other type of oil. Cannabis oil is high in THC which means that it has psychoactive properties. The most common uses of cannabis oil are to get high, as it is commonly used to cook “edibles.”Marijuana oil, cannabis oil or THC oil normally refer to the same thing. An oil made from (Dutch) marijuana with a high concentration of THC. The purpose is to become high, though the medicinal effect becomes more and more important. Cannabis oils generally have a strong aroma, and come in light or dark green and brown colors. Cannabis oils are potent sources of THC which means it will give you a good buzz, but also contains many cannabinoids with therapeutic properties. It is commonly used to treat cancer, depression, chronic pain, and anxiety and is also a powerful anti-inflammatory. Cannabis oil can be applied directly to the skin or consumed sublingually, although many also enjoy using it as an ingredient in cooking edibles. When consuming cannabis oil, keep in mind that its effects take a while. It’s always recommended to start with low doses then work your way through after waiting 30 minutes to an hour.

USAGES OF THC OIL:

Reduces depression, elevates mood
Relieves headaches/migraines/nausea
Increases appetite
Provides relaxation/reduces stress
Relaxes muscles/spasms
Reduces pain/ inflammation /headaches/ migraines
Helps sleep
Reduces anxiety
Reduces nausea, stimulates appetite
Reduces intra-ocular pressure
Reduces seizure frequency/anti-convulsant

Hemp oil

In general with Hemp oil one refers to hemp seed oil.It has nearly indistinguishable levels of THC, which means that it does not give users the classic “high” sensation. The seeds of the fiber hemp are a byproduct of the production of hemp. Hemp oil is made by extracting oil by pressing hemp seeds. Hemp seeds are some of the most versatile and nutritious seeds known to man, hence offering tremendous health benefits if consumed. Avoid purchasing refined hemp oil, which is colorless and has no antioxidants or vitamins. Cold-pressed hemp oil is usually green in color. Unrefined cold-pressed hemp oil has serious medicinal and health benefits particularly Omega-3 and Omega-6 fatty acids which are needed for optimum cellular health. It has no THC content and won’t get you high, although only trace amounts of it can be found in hemp oil. Hemp oil is commonly used as an ingredient in health and beauty products. It’s also used in industrial applications such as in the manufacture of plastics, fuel, lubricants, and paint. Hemp oil burns easily so it isn’t recommended for use in cooking. However, hemp oil can be added in dishes that don’t require cooking such as salads.

USAGES OF HEMP OIL:

  • Hemp oil is great for cooking and a full of nutrients. It can provide a crispy and nutty taste to foods and can be a wonderful replacement for olive oil in salads.
  • It is a great natural moisturizer that can be used after a shower.
  • Hemp oil can be the base for different forms of plastic, instead of petroleum.
  • It is used in the production of paints that are more eco-friendly than petroleum-based paints.
  • It can be used as bio-diesel fuel, like other vegetable oils.
  • Hemp oil is used for making lotions, soaps and even some foods.

CBD Oil

CBD oil is cannabis oil that has a significant content of cannabidiol. It is made from the flowers, leaves and stalks of hemp and not from its seeds like hemp oil. CBD oil has become very popular in the medical marijuana industry, because it can be helpful in the treatment of various conditions without the typical intoxicating effects of marijuana use. Apart from CBD, we have oils that also contain the cannabinoids CBDA, CBC, CBGA, CBD, CBCA. This oil is often diluted with olive oil or hemp seed oil to improve the dosage and taste. CBD oil is the legal health supplement which provides all the health benefits of consuming cannabis in a concentrated form by extracting only the cannabidoids responsible for those biological effects – but without the mind-altering effects.

USAGES OF CBD OIL:

  • Can be used in the treatment of cancer .
  • It is used in the treatment of inflammatory disorders, anxiety, depression, seizures and neurodegenerative disorders.
  • Can be used in the treatment of epilepsy.

Hash Oil

Hash oil is known to be much more potent because it’s a concentrated form of cannabis oil. Just by taking an extremely small amount of hash oil will get you buzzed AF because hash oil contains higher amounts of THC. This means it can get users very high very fast, which may not be a good idea for novice marijuana users. Hash oil is also known as honey oil because of its golden color. Like cannabis oil, it also has medicinal uses for relieving pain, uplifting your mood, and reducing stress. It can be used to make balms or edibles but hash oil can also be smoked, vaped, or dabbed. Hash oils can be applied topically to provide relief from sore muscles and is also popularly used by patients who are suffering from serious, life-threatening conditions thanks to its medicinal value. Hash oil is effective in helping to improve moods as well as stress and pain relief. Hash oil is known to make consumers get high very quickly, which is why it tends to be more popular with a younger crowd who want to get a buzz in a short amount of time.