cbd oil mg for autism

Trial of Cannabidiol to Treat Severe Behavior Problems in Children With Autism

While in the intervention arm subjects will receive EPIDIOLEX, an oral purified CBD solution developed by GW Pharmaceuticals. The formulation is a 100 mg/mL solution, which allows for easy dose titration and administration even to young children. EPIDIOLEX is naturally-derived CBD, and has been found to have a purity of over 98%. The solution includes a sweetener to make it palatable. Dosing is dependent upon each subject’s weight.

The dosage will be titrated over time as follows:

Week 1: 5 mg/kg/day, divided into 2 doses Week 2: 10 mg/kg/day, divided into 2 doses Weeks 3-8: 20 mg/kg/day, divided into 2 doses If a child’s weight changes by greater than 2 kg during the study, the dose will be adjusted to reflect the weight change.

GW has developed a placebo that is identical in color and taste, and will be administered in the same volume as the CBD, so that parents and investigators should not be able to detect differences between the 2 treatments. Dosing is dependent upon each subject’s weight.

The dosage will be titrated as follows:

Week 1: 5 mg/kg/day, divided into 2 doses Week 2: 10 mg/kg/day, divided into 2 doses Weeks 3-8: 20 mg/kg/day, divided into 2 doses If a child’s weight changes by greater than 2 kg during the study, the dose will be adjusted to reflect the weight change.

CBD and Autism

More and more parents are coming out and telling their stories of how their autistic children, as well as their own lives, are improved by the use of Cannabis products. I’m dedicating this article on CBD and autism to my wonderful grandson (age 14) who suffers from autism, so this subject is very dear to my heart.

I hope you get as much from it as I have researched the subject further. This article relates to adults living with autism as well as children and their dedicated parents.

Subjects discussed include cannabidiol (CBD) and other cannabinoids such as THC that have also been found best to help improve the quality of life for autistic patients. I will be covering the following list of topics:

Current Statistics on Autism

In March 2014, The Centers for Disease Control and Prevention (CDC) released new data regarding autism in the United States. This research showed that 1 in 68 children as having (ASD) Autism Spectrum Disorder.

Currently, the worldwide statistics show that there has been a 300% increase in children diagnosed with ASD (autism spectrum disorder).

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Over 3.6 million people in the United States of America live with some form of Autistic Spectrum Disorder.

The population of children afflicted increased by 119.4% in the 10 years from 2000 to 2010.

As of June 2017, about 1% of the world population is estimated to have ASD. This equates to approximately 75 million people.

Estimated cost of autism services in the U.S. is conservatively estimated to exceed $350 billion each year and clearly increasing. Of that cost, the majority of the expense is in adult services. Approximately 75% of ASD sufferers are male.

How CBD Works?

The Cannabis Connection to Autism

Many people are now familiar with the videos of children with seizure disorders being calmed and treated completely with Cannabis. Similarly, we are beginning to see more and more “anecdotal evidence” that the CB2 receptor is found to help ‘connect’ CBD and autism.

In fact, a 2013 study at the Second University in Naples, Italy in association with the Medical School at Stanford University in California found that a malfunctioning or otherwise unhealthy endocannabinoid system may contribute to autism.

The Autism Research Institute has described the use of medical marijuana as has improved symptoms such as “anxiety, aggression, panic disorder, generalized rage, tantrums, property destruction, and self-injurious behavior”.

The aforementioned 2013 study in Italy by Dr’s Piomelli and Manzoni has revealed critically important discoveries about the “Bliss Molecule” anandamide and how Cannabis compounds like CBD and THC can be used to stimulate imbalances in the body’s endocannabinoid system while directly helping to treat autism patients in the process.

They both consider Cannabis as an optimal contributor to scientific approaches to the disorder.

The endocannabinoid system is not only important in regulating healthy behavior, it is now being shown to improve dysfunctional behaviors characterized in autistic patients. Our body’s endocannabinoid system also produces oxytocin which is essential in learning and social behavior. The chaos characterized by the Autism spectrum appears to be calmed significantly by inducing natural cannabinoids to our systems.

According to Dr. Bernard D. Rimland from the Autism Research Institute, the research and studies all show the need to take advantage of ”relatively safe drug like marijuana… The reports we are seeing from parents indicate that medical marijuana often works when no other treatments, drug or non-drug, have helped.”

Studies done recently by researchers at the University of California has confirmed the healing properties of CBD . They further state that their research shows that CBD works against further brain function degradation and has evidence of powerful neuroprotective properties. CBD has also been found to regulate emotion and focus specifically related to their studies on autistic patients.

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Israeli scientists like Dr. Adi Eran are leading the clinical studies and trials for Cannabis as a major cure for Autism among autistic children and teenagers. One of the takeaways from the study has been that cannabis oil rich in CBD is proving out to be the most effective and the best CBD for autism which means that it is not necessary for the patients to have the psychoactive effects (or “high”) or the undesirable and unhealthy side-effects.

Hippocratic Oath

… or Hypocritical Practice?

Although the folksy mythology surrounding the Physician’s Hippocratic Oath to “cause no harm” is surely alive in theory, but is it in practice? Clearly, the answer is no and it’s past time to deal with it head-on. My direct involvement with the medical industry has enlightened me to a different reality and experience from what I had hoped.

The leading cause of death in America in 2017 is not “street drugs”. In fact it never was. However, it is a well-documented fact that the leading cause of death in America is from prescription drugs.

And they continue to wreak havoc on the ignorant and the addicted.

Apparently, most physicians are simply too afraid of their patrons pulling their licenses to practice medicine properly and according to their own “Oath”… another A.M.A. racket played out at the public’s expense.

Well, alert the impotent and “fake” modern media when I point out that some things never change regardless of 44 States voting otherwise . The Feds want to put us all in prison. Meanwhile, physician’s claim they are only applying the core paradigm of medical care in the context of prescribing these drugs for relieving pain.

Physicians and Big Pharma conglomerates continue to produce and prescribe even more dangerous drugs with horrendous and even deadly side effects.

And now, they want to control this “weed”. But I believe they know they can’t keep up this charade much longer. The truth is now coming out with higher velocity.

So just like here at Cannabis Animus, the mounting “anecdotal evidence” from parents, family, friends, and society in general. It IS BEING SHARED with our fellow Americans in spite of the hypocritical behavior of our bureaucratic regulators, rogue drug enforcement agencies, most physicians, and medical industry leaders.

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So Why No Help for Autism?

Does it seem hard to imagine why we are talking about Medical Cannabis and improving neurologic-related disease while the DEA (Drug Enforcement Agency) controls the biggest black market valve ever measured?

By simply classifying the entire Cannabis plant as a Schedule 1 Narcotic , these ignorant or ignoble “agents” consider equivalent in “danger” to heroin and methamphetamine… end of discussion according to the new U.S. Attorney General, Jeff Sessions.

Perhaps one of the world’s top neuroscientists and researchers of the endocannabinoid system puts it best. Dr. Daniele Piomelli reminds us that “anecdotes should not be dismissed… an anecdote is a pointer. It is something that suggests something needs to be either proven or disproven.”

Seems like common sense to me and you, but not to the U.S. Federal government and the American medical-industrial complex. We have observed for decades now how they work hand in hand, one washing the other whenever necessary, and now they want ultimate control over the Cannabis plant itself.

Government Propaganda vs. Clinical Research

The old “Catch 22” effect is evidenced again when we look at the bigger picture of medical research limitations imposed by the Federal government.

The lingering effects from decades of government propaganda, misinformation campaigns, and ignorant talking-heads like Barbra Bush and Nancy Regan are still alive and killing.

And until 20019, we had Jeff Sessions as Attorney General of the U.S., who believes all Cannabis products should be prohibited from cultivation, use, or medical research.

Would it even make a difference if the subject of Autism and CBD therapy was even more deeply researched and patients evaluated?

Since there have been so many funding liabilities, discouragement, and negative leverage applied by the Federal Government on medical Cannabis research in America, there have been relatively few U.S.-based clinical studies on Cannabis and Autism or CBD and autism specifically.

However, there is mounting anecdotal evidence coming from thousands of parents, families, and physicians of people all over the world suffering from the disorder. They report that Cannabis and its cannabinoids like CBD and THC clearly help to improve communication, social interaction, and general behavior positively and noticeably.

Caregivers claim it is helping children, adolescents and adults with autism become happier, lead higher quality lives, and exhibit much-welcomed behavioral improvements.