CBD Oil for Ulcerative Colitis [How It Works]
Ulcerative colitis is a type of inflammatory bowel disease, the other type being Crohn’s disease. However, while the two diseases may share similar symptoms, what is actually going on in the body is different.
While Crohn’s disease may affect any region of the digestive gut, ulcerative colitis (UC) is strictly confined to inflammation of the colon – aka the large intestine. Also, while Crohn’s disease involves inflammation of all layers of the digestive gut, UC is limited to inflammation of the inner lining only.
UC must also not be mistaken with irritable bowel syndrome (IBS), which is a disorder characterized by episodes of constipation, episodes of diarrhea, and relief after going to the bathroom.
In this article, we talk about the possible use of CBD oil for ulcerative colitis. We also ask whether or not the natural cannabis compound may present itself as a viable treatment option based on recent studies and research publications.
Current sufferers of UC will know that conventional pharmaceutical medications for the disorder are both costly and may have dangerous side effects. As such, many have been actively seeking alternative forms of treatment, with CBD appearing as one possible option.
First Things First: What Is CBD… And Is It Legal?
For those UC patients who are still entirely in the dark as to what CBD is, it is essentially a natural component of the cannabis plant. However, it deserves little affiliation with the stereotypical perception of cannabis, as it produces no high whatsoever.
Rather, in the limited amount of years that scientists have studied it, CBD appears to be strictly therapeutic in nature. In other words, it seems to possess many of the health and healing properties of cannabis, without causing any of the mind-altering effects.
CBD oil, which has become the most popular form of CBD as a therapy, is essentially a natural extract from raw cannabis plant material. It can come from actual strains of marijuana (which contain THC), or from industrial hemp, which is similar to marijuana but contains less than .3% THC.
On a federal level, CBD products that are extracted from industrial hemp are legal to possess and use in all 50 U.S. states. On the state level, however, there are still a few regions where use and possession of the compound is not so widely accepted. In North Carolina, for example, police recently arrested a vape store owner for selling bottles of CBD oil, even though the oil came from perfectly legal industrial hemp.
Regardless, it’s important to point out that the majority of top U.S. CBD oil manufacturers are shipping to all 50 states. No matter what part of the country you live in, it is easy to order online and have the product shipped to your home.
What Is Ulcerative Colitis – And How Is It Typically Treated?
As we’ve mentioned, ulcerative colitis is defined as persistent inflammation of the colon, aka the large intestine. This chronic inflammation may range from mild to severe, and in the latter instances, it is common for the colon’s inner lining to develop painful lesions, sores, and other forms of irritation.
UC symptoms are relatively uniform in nature, and can include:
- Loose and urgent bowel movements
- Persistent diarrhea
- Abdominal pain
- Bloody stool
- Abdominal pain/cramping
- Loss of appetite
- Weight loss
- Low energy and fatigue
- Inhibited growth and development (in children)
It’s important to note, however, that symptoms of ulcerative colitis are non-persistent in nature; a victim may go several weeks or even months with no symptoms at all, only to experience a severe flare-up seemingly out of nowhere.
How Is Ulcerative Colitis Currently Treated?
There is currently a wide range of treatment options available for patients with ulcerative colitis. These may range from strong prescription pharmaceuticals in the most severe cases, to generic OTC drugs in milder instances.
Prescription medications commonly include:
- Antibiotics such as metronidazole and ciprofloxacin
- Aminosalicylates (5-ASAs) that function by reducing inflammation in the intestinal lining
- Corticosteroids that may reduce inflammation by suppressing the immune system
- Immunomodulators that suppress the body’s immune response
- Biologics that target a specific pathway to reduce inflammation
Non-prescription medications for UC may include generic over-the-counter (OTC) drugs such as antidiarrheals, anti-inflammatory analgesics (pain relievers), and even nutritional supplements that work to lower instances of chronic intestinal inflammation.
In more severe instances that are not responsive to conventional treatment, surgery may be necessary to remove portions of the large intestine that are most affected. In some instances, it is possible to cure ulcerative colitis with surgical removal of the colon (via a process known as a colectomy). However, invasive surgery always presents its own risks – particularly among elderly patients.
What Causes Ulcerative Colitis?
In terms of factors that may influence the onset or development of ulcerative colitis, doctors and researchers still have not been able to pinpoint an exact cause of the disease. It’s thought that initial onset may stem from an immune response to a bacterial or viral infection of the colon; in most instances, this inflammatory response will subside after the infection has cleared, but for whatever reason, inflammation seems to persist long-term in those that develop symptoms of the disease.
Genetics also seems to play a significant role in the onset of UC, since it can run in families. Ulcerative colitis also has what is called a ‘bimodal distribution,’ which means there’s a risk of it occurring at a younger age (in the 20s and 30s) and then again at an older age (60s and 70s). According to the Centers for Disease Control and Prevention, 3 million people in the country suffer from inflammatory bowel disease, the majority of which have ulcerative colitis.
CBD for Ulcerative Colitis – How Might It Work?
Simply put, it is hypothesized that CBD may be effective for ulcerative colitis because of its ability to function as an anti-inflammatory. The National Institute of Health’s PubChem database, for example, lists cannabidiol (the scientific name for CBD) as being “devoid of psychoactivity,” and as having both analgesic (pain-relieving) and anti-inflammatory properties.
Moreover, few people know that the U.S. government currently holds a patent on CBD for (among other things) its role as an anti-inflammatory agent, which states: “Cannabinoids have been found to have antioxidant properties … [making them] useful in the treatment of a wide variety of oxidation-associated diseases, [including] inflammatory and autoimmune diseases.”
What’s equally as intriguing, however, is the fact that the endocannabinoid system, or ECS, is known to have an abundance of receptors located throughout the digestive system – including the lining of the colon.
Unfortunately, there have not yet been multi-stage clinical trials on the use of CBD oil for ulcerative colitis. The FDA has recently approved a CBD-based drug called Epidiolex for the treatment of intractable forms of epilepsy, but as of now, physicians are unable to prescribe the cannabis-based medication for any ulcerative colitis patients.
Current Research on CBD for Ulcerative Colitis
Even though the requisite clinical trials are still lacking, there have been a surprising number of specific scientific investigations carried out on the effects of CBD for ulcerative colitis. Here is a list of several of the most relevant ones:
CBD for Ulcerative Colitis: The Studies
took place in Israel from 2011 to 2016. Researchers wanted to find if there was any correlation between cannabis consumption and IBD (inflammatory bowel disease). They observed 127 patients, all who had been successful in their application to use cannabis. By using a variety of biomarkers, including mode of consumption and rate of consumption, they collected data from each participant using the Harvey-Bradshaw Index. Not only did the patients themselves report significant improvements in pain, but the index, where a lower score is considered better, decreased from 0 to 5.0. Despite the positive response, there were minor side effects, including dry mouth and memory decline.
- A 2011 report in PLOS One claims that CBD presents a “new therapeutic strategy” in treating inflammatory bowel disease. The goal of the study was to monitor the effects of CBD on intestinal biopsies from actual patients with ulcerative colitis, as well as intestinal segments of mice with induced intestinal inflammation. Results showed that CBD was able to “counteract the inflammatory environment” in both instances. This led researchers to claim that the natural compound presents a “new therapeutic strategy” in treating various forms of IBD, including ulcerative colitis. However, this study was only done on ex vivo samples and does not necessarily represent what would happen in the body.
- A 2018 study looked into the efficacy of CBD extract in patients 18 and older with ulcerative colitis. While it did not find a difference in the remission rates between those using CBD and those using a placebo, the study did suggest that CBD extract may be beneficial for symptomatic treatment.
- Another 2018 study was unable to draw any conclusions about the safety or efficacy of CBD oil in those with ulcerative colitis, suggesting more research needs to be done.
Final Thoughts on CBD Oil for Ulcerative Colitis
A lot of research still needs to be done to determine the efficacy of CBD oil for those with ulcerative colitis. As things currently stand, there is some evidence that CBD oil can have a beneficial effect, but there is no good information about dosing or route of administration.
Additionally, CBD may provide extra symptomatic relief for those suffering from the disease. What is important to keep in mind is that if you are suffering from ulcerative colitis, you should still take all medications prescribed by your doctor. If you are considering going off of your medications or beginning alternative treatments (including CBD), talk with your doctor first to see if it is a good idea for you.
If you do end up trying CBD, there are several high-quality CBD oil manufacturers currently selling legal products to all 50 U.S. states, but as always, we recommend that everyone do their own research (or better yet speak with their physician) in order to find a product that will work for them.
Lastly, it’s important to recognize that none of the information in this article should be taken as medical advice, and should not be used to diagnose, treat, cure, or prevent any disease.
Top 7 Best CBD Oil for Colitis
However, these conditions can also affect other areas like the mouth or anus due to their systemic nature. It means it can attack any part of the body where blood vessels lie close together, including joints, skin, etc.
Ulcerative colitis is an inflammatory disease of the inner lining of your colon and rectum. Unlike Crohn’s Disease, ulcerative colitis causes inflammation only in the gut wall. It does not affect any other part or organ in the body as Crohn’s does.
CBD oil is an effective treatment for ulcerative colitis, but the most efficient way to take it varies depending on your needs. Let’s find out which brands are providing the best CBD oil for colitis.
Top 7 Best CBD Oil for Colitis
SpruceCBD: Lab Grade Oil – Editor’s Choice
- Medterra: CBD Oil – Best Affordability
- CBD Pure: Hemp Oil – Best Expertise
- Joy Organics: Premium CBD Organic Tinctures – Best Natural
- Hemplucid CBD Oil – Best Full-Spectrum
- cbdMD: CBD Oil Tincture – Best for Flavors
- Endoca: CBD Oil – Best for Medium Strength
1: Spruce CBD: Lab Grade CBD Oil – Editor’s Choice
Spruce is a CBD brand dedicated to making American-made products. This company works hard on creating the best oils and has established itself as one of our favorite brands.
This highest-quality CBD comes from organic hemp grown in Kentucky and North Carolina, using a time-tested strain sourced for over 200 years.
Spruce is the only company that uses a moonshine extraction method to extract CBD from hemp, which is pretty safe and effective. With lab-tested hemp extracts, CBD oils provide all of the cannabinoids and terpenes found in original plants.
CBD bottles come in two different potencies with a pleasing peppermint taste. The higher potency has 80 mg of CBD per ml, while the lower has 25 mg of CBD per ml.
- Two different potencies
- USA-grown hemp
- Third-party lab tested
- Full-spectrum hemp extracts
- Lab grade
- All-natural ingredients
- Zero high
- Lack of potencies
2: Medterra: CBD Oil – Best Affordability
As a reputable brand, Medterra has several CBD products on its list. These include creams, tinctures, edibles, oils, and supplements. If you need something for your pets, they also have supplies available.
The CBD tincture comes in four potencies, 500 mg, 1000 mg, 3000 mg, and 6000 mg. CO2 extraction is the gold standard of methods for extracting CBD oil from hemp seed. This method can remove THC and impurities to ensure high-quality product lines.
These CBD products are certified by the U.S. Hemp Authority, which issues guidelines on stringent hemp processing to ensure the quality and safety of CBD products with third-party testing.
MCT is added to this product as a carrier oil and provides fatty acids. In addition, MCT helps the body absorb cannabinoids.
- Lab purity testing
- Isolate CBD oil drops
- Four different strengths
- US Hemp Authority certified
- Organic MCT oil
- No pesticides
- Made in the USA
- CO2 extraction process
- No flavor options
3: CBDPure: Hemp Oil – Top Notch Quality
CBD pure was founded in 2016 to share CBD products of the highest quality. They grow their plants organically, without using pesticides or herbicides, located in Colorado and Washington.
The company tests its products and releases the results on its website. The Certificate of Analysis outlines essential information such as cannabinoids, terpenes, solvents, pesticides, etc.
All of their organic food products are ethically sourced from small farms. These CBD products are affordable, and they even offer coupons to help reduce the cost. You can apply these coupons at checkout for all CBD items at their store.
You get full-spectrum hemp oil: 300 mg, 600 mg, and 900 mg per 30cc bottle. CBDPure is confident that their products work for various health conditions and ailments, and therefore, they offer a 100% money-back guarantee.
- Three different strengths
- Colorado-grown hemp
- Independent lab results
- Full-spectrum hemp extract
- No preservatives
- 90-day money-back guarantee
- Organic No artificial flavors
- No flavor choice
4: Joy Organics: Premium CBD Organic Tinctures – Best Natural Product
Joy Organic is a CBD oil brand that uses only phytocannabinoid-rich hemp to create the promised effect. The range of 112 cannabinoids in its oils also includes rich amounts of essential minerals, terpenes, and other cannabinoids like CBG.
Both full-spectrum and broad-spectrum CBD products are tested to ensure that they meet quality standards. That includes both an in-house test and a third-party lab that generates certificates for the customers.
Joy Organic is proud to use only the highest quality US-grown hemp for its oils and extracts. American standards are higher than other countries, so you know that Joy Organics always provides consumers with safe, high-quality products they can trust.
CBD products come in four flavors: orange, tranquil, natural, and mint. Each flavor comes with different potency, 250mg, 500 mg, 1000 mg, and 1500mg, in a 30 ml bottle. In addition, the CBD undergoes a nanotechnology emulsion technique to make it more bioavailable.
- Both full- and broad-spectrum CBD oil
- Four different potencies
- 30 ml/bottle
- USA-grown hemp
- USDA certified
- Source not mentioned
- No international shipping
5: Hemplucid CBD Oil – Best Full-Spectrum
Hemplucid uses the finest hemp to produce some of the best CBD products for ulcerative colitis and other conditions. They care about making sure you get what you need and promise transparent lab results. Customers can choose from a variety of different potencies and carrier oils in the Full-Spectrum CBD Tincture. This product is available with either hemp seed oil or MCT (medium-chain triglyceride) oil as its base.
Furthermore, you have the option to purchase bottles ranging anywhere between 250 mg to 2000mg of CBD per bottle. Hemplucid is a pure CBD oil that contains a whole range of cannabinoids and terpenes found in cannabis. If you are looking for an organic hemp extract, Hemplucid provides it without artificial colors or flavorings.
- Potencies: 250 mg – 2000 mg
- Third-party lab-tested
- USA-grown hemp
- Cold-pressed hemp seed oil
- Certificate of Analysis
- Wide range of strengths
- No artificial flavorings
- No synthetic colors
- Entourage effect
- Several cannabinoids
- A bit pricey
6: cbdMD: CBD Oil Tincture – Best for Flavors
cbdMD is a prominent name in the CBD industry, offering a broad series of CBD products, including for adults to help relax after work or take care of children during playtime.
Their tinctures will make you feel better from head to toe by easing aches and pains while promoting sleep at night, let alone colitis. In addition, these products retain all of the beneficial terpenes and cannabinoids present in whole-plant formulations without any THC.
This broad-spectrum CBD oil is available in mint, berry, and orange flavors. It comes in 1000 mg and 1500 mg option which has been third-party lab-tested to ensure quality control. With regular use of CBD, you may notice results in two to three weeks.
- 1000, 1500 mg potencies
- Third-party testing
- Superior broad-spectrum formula
- USA hemp
- GMP certified
- Four delicious flavors
- Different serving and strengths available
- Not cheap
7: Endoca: CBD Oil – Best for Medium Strength
The cheap 300 mg CBD oil Endoca is an excellent option for beginners, but 900 mg CBD oil is the best option if you want to get started with something more potent. It is an easy and inexpensive method of treatment instead of your serious medication routine.
Endoca makes it an easy task to adjust the optimum dose for your needs. Each drop of oil contains one milligram of CBD, so you can easily personalize how much is suitable for your body and conditions like colitis.
This product is full-spectrum with all of the additional cannabinoids and terpenes in it. It is extracted from organically grown hemp, which is GMP certified.
Endoca is a CBD oil brand that focuses on sustainable practices. The UN has recognized it for its efforts and works closely to test each product through an independent laboratory.
- Two different sizes
- Full-spectrum formula
- Different strengths
- USA-sourced hemp
- Satisfaction guaranteed
- Many flavors available
- Relatively expensive
Symptoms of Colitis
Scientists are not entirely sure what causes inflammatory bowel conditions like ulcerative colitis. However, they suspect that hereditary factors play a significant role in their development.
As these conditions are caused due to the immune system attacking healthy cells in the body, it is speculated that chronic inflammation develops because of this “attack” by our immune system’s attack on our bodies.
Its possible symptoms are as follows:
- Loss of appetite
- Loose and regular bowel movements
- Abdominal pain
- Bloody stool
- Low energy
- Continuing diarrhea
How to Take CBD Oil for Ulcerative Colitis?
Many people turn to CBD; a legal alternative one must not use without medical advice. People who use the product might also consider using cannabis to control their pain and other side effects of their illness.
For those with IBD specifically, it could play a role in increasing quality of life through its effects on symptoms such as nausea and appetite loss.
If you have inflammatory bowel disease, aim to take CBD orally or through the bloodstream by putting tincture drops under your tongue and inhaling the vapors.
One might achieve significant health benefits from incorporating the many CBD products available in the market into their lifestyle.
The Advantages & Disadvantages of CBD Oil for Colitis
CBD possesses a lot of advantages, and even good things come with their disadvantages. Let’s take a look at them:
Pros of CBD Oil
- CBD has anti-inflammatory properties that could potentially relieve ulcerative colitis symptoms.
- A variety of studies suggest that CBD oil may be an effective treatment for inflammatory bowel diseases.
- CBD consumption does not make people high like THC, the psychoactive substance in medical marijuana.
- CBD oil products are available across the USA in legal locations as long as you have a prescription.
- A study released in 2018 has found that cannabidiol may help with drug addiction and substance abuse due to its non-addictive nature.
Cons of CBD Oil
- CBD has shown promise in treating ulcerative colitis on lab rats, but its effectiveness still needs to be tested in clinical trials with humans.
- CBD users may experience adverse effects, such as dizziness, nausea, fatigue, and headache.
- The Food and Drug Administration (FDA) has not approved any CBD product except Epidiolex.
- By using CBD and other medications together, it could affect how these drugs work. That may lead to severe side effects for the patients.
The Final Thought
As of now, there is not a lot of research conducted on CBD oil and ulcerative colitis. There is only some evidence that it can have a positive effect, but there is no information about proper dosing or administration methods.
If you have ulcerative colitis, CBD may provide extra relief. However, if you decide to take it as an alternative treatment or go off of your medications, it is advised to talk to your doctor first.
Although not everyone may experience the same effects, CBD is a safe and legal oil that has been shown to decrease anxiety. Lastly, it is crucial to recognize that none of the information in this article should be used as a piece of medical advice.
1: How much CBD oil is required for colitis?
That may be according to a “sweet spot” or dosage where symptoms resolve, but a higher or lower dose will not have the same remission effects. Therefore, it is advisable to consult your physician first.
2: Is CBD oil effective for colitis?
CBD can help with IBD symptoms by decreasing pain and inflammation. CBD has been shown to improve both humans and animals suffering from IBD, but more research is needed on its effectiveness.
3: Is CBD oil safe for pregnant women?
There is no reliable information regarding its use during or after pregnancy. That is why pregnant and breastfeeding women should not consume CBD as it can affect the baby.
4: Can I overdose on CBD oil?
No, that is why CBD oil is a safe and healthy alternative to traditional medication. It has no adverse side effects, making it the perfect option for those who want an all-natural way to treat their ailments.
5: Can I get high with CBD oil?
No, these products are not psychoactive, so you can enjoy the benefits of natural cannabis without worrying about getting high with their supplements.