Biomechanical Effects of Δ9-Tetrahydrocannabinol (THC) and Cannabidiol (CBD), the Major Constituents of Cannabis, on Tendon to Tendon Healing in a Sprague Dawley Rat Achilles Tendon Surgical Repair Model
Use of Cannabis is common amongst athletes and the U.S. population at large. Use of Cannabinoid Oil is being increasingly utilized for a number of different pathologies, injuries, and ailments due to anecdotal evidence of its efficacy. Due to the current United States Opioid crisis, Δ9-Tetrahydrocannabinol (THC) and Cannabidiol (CBD), the two major constituents of cannabis, are currently being evaluated as potential safer alternatives to narcotic pain medicines. The effects of recreational and/or therapeutic THC and CBD on musculoskeletal injury and healing however remain largely unknown. Our purpose was to evaluate the biomechanical effects of THC and CBD on tendon to tendon healing in a Sprague Dawley Achilles Tendon injury and surgical repair model.
33 Sprague Dawley rats were randomly assigned into control (1 ml/kg/day of vehicle containing 5% Cremaphor, 5% ethanol, and 0.9% saline n=12), THC (3 mg/kg/day n = 12), or CBD (3 mg/kg/day n=9) treatment groups. Surgical transection and repair of the Achilles tendon was performed and all rats began subcutaneous administration of their respective drug treatment the day of surgery and for 4 subsequent days, followed by sacrifice. Load to failure and stiffness were calculated from load displacement data during tensile load testing on a MTS machine. One-way ANOVA with heterogeneous variance was utilized for evaluation. Means and 95% confidence intervals were also determined.
The CBD group demonstrated the highest mean load to failure of 17.5 N (15.1-19.8 N), with the THC group having the second highest mean load to failure at 17.3 N (15.3-19.2 N), and the control group reporting the lowest at 15.2 N (12.1-18.3 N). No statistical difference was observed between CBD/control (p = 0.25), THC/control (p = 0.29), or CBD/THC groups (p = 0.92, Figure 1A). The THC group reported the highest mean stiffness of 3.9 N/mm (2.7-5.1 N/mm). The CBD and control groups demonstrated mean stiffness values of 3.5 N/mm (2.9-4.1 N/mm) and 3.5 N (2.7-4.3 N/mm), respectively. No statistically significant differences were observed between THC/control (p = 0.51), THC/CBD (p = 0.50), or CBD/control groups (p = 0.96) for stiffness (Figure 1B).
Our investigation demonstrates that subcutaneous administration of CBD resulted in the highest mean load to failure while THC administration resulted in the highest mean stiffness of the three groups. This did not result however in a statistically significant difference between groups. In our small animal tendon-to-tendon repair model, use of THC or CBD did not result in decreased biomechanical characteristics, and there was a trend toward improved ultimate strength and stiffness as compared to control. Further evaluation with larger numbers of animals, and evaluating the potential synergistic effects of THC and CBD administered together are warranted.
CBD Oil for Tendonitis (UK)
I have found myself having to stop training quite often due to moderate to severe tendonitis of the elbows and wondered whether anyone here was able to recommend CBD oil for joint pain that might go some way to treating the condition?
From trustpilot reviews etc, difficult to make a decision as to whether to go with just CBD or an oil with a slight THC content as well.
Any guidance/recommendations hugely appreciated
Thanks in advance
Can't comment regarding CBD.
However I noticed banded mini workouts have helped me massively with tendinitis. Performing 100 reps per set of curls, extensions, leg extensions and leg curls have helped my recovery massively.
Hi, thanks for replying.
I'm waiting on delivery of a theraband flexbar and hoping that using that will go some way to making the tendons stronger
I've tried a wide variety of CBD oils for pain due to all the hype, and personally I've found they don't do a thing (although they do help me sleep. which might help recovery indirectly). THC can make you stop caring about the pain for a bit, but neither is going to cure your injury.
If you're injuring the same thing repeatedly you're either not letting it heal or doing something dumb like overworking it the second you're back to training. No over-the-counter drug will fix this – the pain is coming from something. Try an extended period of not aggravating it by skipping rolling or doing lighter workouts. For me it takes about 3 months for tendon injuries to calm down.
The Best CBD Products for Tendonitis Injury (Creams, Capsules, and Oils)
Both scientific research and anecdotal evidence are showing that CBD can reduce inflammation. This research has lead to thousands of people now using CBD to reduce the pain associated with tendonitis. With that said, what are the best CBD products for tendonitis pain?
Ignore pain with the best CBD products for tendonitis injury.
Tendonitis is a condition that stays for a long time once you have it. So use some of the best cbd for tendonitis injury and enjoy pain-free movements again.
Table of Contents
CBD Products for Tendonitis Injury
Tip: Use code “mycbd10” for 10% of all products sitewide
With a thicker and more concentrated solution, this is our best CBD salve for targeted tendonitis pain . The first thing you notice when you open the container is the delightful aroma of fresh lemon. The second thing you will notice is the dense nature of the product. As such, you’ll have to dig into the product before you can apply it. The highly concentrated consistency makes it perfect for applying to small areas of inflammation, like tendonitis. The nourishing hemp salve also contains other natural ingredients that reduce dryness and promote softness. Made from natural, food-grade ingredients.
Ingredients: CBD (cannabidiol), Coconut Oil, Beeswax, Cannabis Sativa Seed Oil, Citrus Medica Limonum (Lemon) Peel Oil, Citral, Vanilla, Vitamin E.
With added menthol, this is our best CBD cream for tendonitis pain. Infinite CBD combines CBD oil, peppermint, menthol, eucalyptus, and camphor to create a product to calm joint inflammation. The cream is available in three sizes: 2oz 250mg, 2oz 1000mg, and 8oz 1000mg. The freezing cream glides across the skin with ease and offers great value for money.
Ingredients: CBD oil, peppermint, menthol, eucalyptus, and camphor
Trusted Third Party Lab Tested
This powerful duo features an extra-strength CBD pain relief cream and CBD oil for results you can feel inside and out. Diamond CBD’s CBD oil with MCT delivers all the benefits of high-quality CBD with MCT oil’s essential fatty acids for optimized energy to help you kickstart your day.
CBD Oil Biotech’s Pain Relief Cream targets sore muscles and joint pain to deliver instant relief for a topical solution. With a heavy focus on continuous research and development in hemp, CBD Oil Biotech and Diamond CBD work hard to produce the finest and purest quality CBD products on the market.
- No Harmful Toxins
- Third-Party Lab Tested
- Supercritical CO2 Extraction
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BioTech also has a Topical Pain Relief Bundle available for 54% off here
This buyer’s guide is frequently updated with the latest and best CBD products for tendonitis inflammation.
If you’re suffering from an inflamed injury, I feel for you. In fact, I’m going through a similar issue with my back pain. Even though many over-the-counter painkillers are the typical go-to product for adults suffering from pain, they are often associated with negative side effects. Fortunately, new research is showing that cannabidiol is effective for fighting inflammation.
The effect of cannabinoids on inflammation has been well-researched, especially compared to other conditions. These studies show that CBD can reduce inflammation . The anti-inflammatory properties of cannabidiol make topical CBD products ideal for tendonitis and other inflammation-related injuries.
How to find the best CBD cream for tendonitis?
Thinking about using CBD cream to reduce tendonitis pain? Then you should know that not all topical products are held to the same high standard. There are several factors at play. Let’s delve further.
Whether you want to use the best CBD cream for tendonitis or take advantage of the many cannabidiol health benefits, the quality indicators are basically the same. With that said, additional ingredients can make one CBD product better than another CBD product for specific conditions, like tendonitis.
The cannabinoid compound is typically safe and rarely comes with any side effects. However, it can be tricky to know which CBD to purchase. When searching for the best CBD lotion for tendonitis pain, it’s worth keeping the following mind:
Lab results – When shopping for CBD products, you want to purchase from a CBD company that publishes regular third-party laboratory results. These results allow consumers to see that the topical product can be used with confidence.
Ingredients – Please check the label on our products before using them. This is especially important for those that are allergic to specific topical ingredients.
Price – Paying for tendonitis treatment doesn’t have to be expensive. Using CBD topicals can be an effective way to reduce the costs associated with the injury. With that said, you don’t want to be paying more than you should be.
Whatever form of CBD you prefer to use, all products in this guide are designed to reduce the pain and inflammation associated with tendonitis. Happy shopping!