cbd oil for parkinson’s patients

CBD Oil for Parkinson’s Disease: Can It Help?

Cannabidiol (CBD) oil is a hemp product commonly used as a natural remedy for many ailments. But can it help people with Parkinson’s disease (PD)? PD is a debilitating movement disorder of the central nervous system, and it currently has no cure. However, symptoms of Parkinson’s can be managed with the help of some drugs and natural remedies, including CBD oil.

What Is CBD?

CBD has grown in popularity in recent years due to its perceived health benefits. CBD is a nonpsychoactive byproduct of the cannabis plant. While marijuana (including medical marijuana) contains a combination of both CBD and tetrahydrocannabinol (THC), hemp products contain nearly undetectable levels of THC and have a higher CBD content.

With the passage of the 2018 Farm Bill, production and distribution of industrial hemp were legalized across the United States. CBD is now more readily available to those who want to take advantage of its beneficial effects. CBD can be consumed in multiple forms, including oils, creams, or edible products like gummies, lollipops, or chocolate. Epidiolex (cannabidiol) was approved by the U.S. Food and Drug Administration for the treatment of Dravet syndrome and Lennox-Gastaut syndrome, two rare forms of epilepsy.

How Does CBD Work?

Both THC and CBD are cannabinoids, or compounds found in cannabis plants. They each work in complex ways in the brain. When taken together (such as in marijuana), they influence the body’s endocannabinoid system, a network that detects and reacts to the presence of cannabinoids in the body. This system helps regulate a variety of processes, including appetite, cell division, inflammation, stress, and vomit suppression.

There are two identified cannabinoid receptors in the human body: type 1 cannabinoid receptor (CB1) and type 2 cannabinoid receptor (CB2). CB1 receptors are found mostly in the brain and central nervous system, while CB2 receptors are found in the gastrointestinal tract and organs such as the spleen. Anandamide and 2-arachidonoylglycerol are brain cannabinoids that also work within this system.

When CBD enters the body alone (without THC), it acts differently. Scientists believe that CBD acts either directly or indirectly on several types of G protein-coupled receptors, including serotonin receptors. CBD can also affect ion channel receptors, such as vanilloid type 1 (TRPV1) receptors. However, there is still much to be learned about how CBD acts within the body.

What is known is that CBD seems to help with inflammation. CBD has been shown to reduce inflammation associated with inflammatory bowel disease. Further work has demonstrated that CBD treatment reduces the pain and nerve damage associated with osteoarthritis. Some of this pain reduction may be due to how CBD acts on TRPV1 receptors. CBD reduces inflammation by regulating cell death, preventing the birth of new cells, and suppressing cytokines and immune cells (such as T cells).

How Can CBD Help Parkinson’s Disease?

CBD may have the potential to help individuals with PD manage motor symptoms such as dyskinesia (the loss of control of voluntary movement). This is because of CBD’s anti-inflammatory actions. CBD may also help movement due to its neuroprotective actions in the nigral-striatal pathway and basal ganglia, areas known to be dysregulated in individuals with PD.

Members of MyParkinsonsTeam are talking about CBD and how it has improved their quality of life, or that of their loved ones. One member shared, “My mother suffers from Parkinson’s and most times has trouble sleeping. The meds they have her on don’t always stop the shaking. I finally convinced her to try CBD. The effects are amazing. She sleeps better, and it normally stops or at the least lessens the shaking.”

CBD may also be able to help with the nonmotor symptoms of PD, such as psychosis. One clinical trial demonstrated that giving oral CBD (compared to placebo) to six individuals over a period of four weeks lowered psychosis behavior.

What To Know Before Taking CBD

The use of CBD is not without risks or adverse effects. Some people have reported side effects of sleepiness, diarrhea, or changes in appetite or weight. There is also growing research to suggest that high doses of CBD may lead to liver toxicity. Not much is known about potential drug interactions with CBD products such as oils.

CBD may not work for everyone, and there is still much to be learned about its use. Be sure to talk to your doctor before beginning to take CBD products.

Building a Community

MyParkinsonsTeam is the social network for people with Parkinson’s disease and their loved ones. On MyParkinsonsTeam, more than 79,100 members come together to ask questions, give advice, and share their stories with others who understand life with Parkinson’s disease.

Have you tried CBD products to help manage your Parkinson’s disease? Share your experience in the comments below, or start a conversation by posting on MyParkinsonsTeam.

CBD Oil in Parkinson’s Disease

It is a neurological disease in which nerve cells gradually decrease in the brain. This leads to serious problems with, for example, movement control and other accompanying symptoms. Unfortunately, the treatment of Parkinson’s disease is in the dark. Patients are currently receiving uncomfortable information about their average life expectancy from 6 to 9 years. However, they can still be helped to survive this period with the least possible health problems. And that’s what CBD is for at Parkinson’s disease.

Unfortunately, the treatment of Parkinson’s disease is in the dark. Patients are currently receiving uncomfortable information about their average life expectancy from 6 to 9 years.

How does CBD help with Parkinson’s

Experience with CBD oil in Parkinson’s disease has shown that this substance can positively affect several symptoms of the disease. These include:

  • improvement of appetite,
  • elimination of insomnia,
  • depression or anxiety,
  • anti-inflammatory effect, or reduction of cramps.

On the Internet you will also find a number of forums on the topic of CBD and Parkinson’s disease to help answer all questions. Cannabis products in Parkinson’s disease are currently extremely effective and popular. Medical cannabis in Parkinson can be a great way to prevent side effects of other drugs and allow you to spend treatment in a much better physical or mental condition.

Parkinson’s Disease

Parkinson’s disease is a progressive, degenerative disease of the peripheral (PNS) and central (CNS) nervous systems. It most often occurs around the age of 60. However, in early onset Parkinson’s disease, it manifests itself in approximately 10% of cases before reaching the age of 40 years. A unique phenomenon is Juvenile Parkinsonism, which occurs even before the 20th year. In this case, it is probably a congenital form of disease associated with specific gene mutations.

In Europe alone, around 1.2 million people are diagnosed with PD. This ranks it second in the list of neurodegenerative diseases.

Parkinson’s symptoms

Primary symptoms of Parkinson’s include:
  • muscle stiffness,
  • tremor,
  • shuffling instead of walking, slowing of movement, and imbalance.
Atypical symptoms of Parkinson’s include:
  • dementia,
  • confusion,
  • anxiety and depression.

When we mention the risk factors for Parkinson’s disease, we cannot forget about age. But scientists also include toxic substances or infections in triggers. Life expectancy in Parkinson’s disease depends on its course and species.

Lewy Bodies Dementia

In Dementia with Lewy Bodies (DLB) and Parkinson’s disease with dementia, the average survival time is about 7 years.

Multisystemic atrophy

In multisystemic atrophy (sporadic progressive neurodegenerative disease with a combination of parkinsonism, autonomic dysfunction and cerebellar manifestations), the median survival is 6-9 years. However, death in Parkinson’s disease may occur earlier, for example due to accidents.

In multisystemic atrophy (sporadic progressive neurodegenerative disease with a combination of parkinsonism, autonomic dysfunction and cerebellar manifestations), the median survival is 6-9 years.

A positive family history in Parkinson’s disease is found in about 10 to 15% of patients. Congitive disorders, especially dementia syndrome, are a major inconvenience. It is characterized as a deficit in at least two areas:

  • attention,
  • orientation,
  • visionary social orientation,
  • verbal ability,
  • executive functions,
  • counting,
  • practice,
  • abstraction,
  • judgment.

These deficits consequently lead to an overall reduction in intellectual abilities and negatively affect standard daily activities. This is accompanied by psychotic symptoms or personality changes in Parkinson’s disease.

Patients have the possibility to apply for the issuance of a card of a natural person with severe disabilities. In order for the document control in Parkinson’s disease to be smooth, the insured person must have a proven long-term unfavorable health condition, which has caused his/her decrease in the ability to perform a gainful activity to be determined by an medical appraiser. The issuance of a card shall promote the social integration of a natural person with severe disabilities into society and the maintenance of his or her human dignity.

Treatment of Parkinson’s Disease, Medicines and Cures

Treatment options

At present, every more advanced country already has all possible conventional therapeutic options for treating Parkinson’s disease. However, it cannot be cured completely. In the early stages, the principle of treatment is mainly considered to be the replacement of absent dopamine with specific transdermal patches or medications. However, other symptoms such as cognitive impairment, sexual activity, depression or anxiety should also be considered during treatment.

Pumping systems and deep brain stimulation are used for advanced stages of the disease. It’s built to introduce electrodes into the deeper structures of the brain. These are then stimulated by a neurostimulator. Stimulation is a way to reduce the dose of medicines, thereby preventing unpleasant side effects. Pumping systems continuously deliver medication through a pump to the small intestine or subcutaneously. Their advantage is the elimination of motor fluctuations that occur during advanced stages of the disease.

No matter what form of treatment it is, special rehabilitation is always necessary. There can be no lack of psychological support for patients or dietary adjustment. Again, it is important that the patient accepts the existence of the disease and the entire course of treatment as necessary.

Parkinson’s disease drugs

The most commonly used medicines in the treatment of Parkinson’s disease include:

  • Levodopa,
  • Levodona/Carbidopa,
  • Anticholonergics,
  • Amantadine
  • Selegiline.

Levodopa is considered the most effective active substance in most cases. It is an amino acid similar to the basic building blocks of proteins. At the first moment, it is absorbed into the bloodstream and then the interface between blood and brain tissue passes. It turns chemically into dopamine in the brain. Changes in the symptoms of Parkinson’s disease were achieved by adjusting the amount of dopamine to almost normal values. Levodopa is suitable for most patients and almost all symptoms.

The combination of Levodopa with Carbidopa will eliminate the side effects of the active substance. In some cases, nausea occurs, which is caused by the substance dopamine, but which arises outside the brain, where it does not even have therapeutic effects. Carbidopa blocks the conversion of levodopa to dopamine. Anticholinergics inhibit the action of the neurotransmitter acetylchiline. Amantadine is a chemical that has multiple effects in the brain, increases dopamine release and has antichilnergic effects. Selegiline prolongs the effects of dopamine and can intensify them.

CBD OIL AND PARKINSON'S DISEASE: Everything you Need To Know About Using CBD Oil to Treat Parkinson’s Disease

While CBD does not provide a final cure for Parkinson’s, it can bring a significant improvement in the fight against the illness’s terrible symptoms. This is why more studies need to be embarked upon in this direction, because everybody suffering from a disease, especially one that affects the brain, would like to have a chance to lead a decent life and not become entirely dependent on another person for care and everyday tasks.

CBD could redeem dignity and self-esteem for people suffering from Parkinson’s, also improving their morale by treating depression, stress, and anxiety. It also allows people to sleep better and be more active, by reducing pain and improving mobility. All these reasons should be good enough in order for more studies to take place in this particular area.
Until an actual cure is found, a treatment that improves life quality will be more than welcome. CBD is entirely safe to be used for medical purposes because it does not have a psychoactive effect. In fact, it helps diminish psychotic episodes, promoting relaxation and a calmer state of mind.
While it may take a while for researchers to fully understand how CBD works in protecting our brain, the positive results speak for themselves and such treatment should be made available as soon as possible.
While CBD does not provide a final cure for Parkinson’s, it can bring a significant improvement in the fight against the illness’s terrible symptoms. This is why more studies need to be embarked upon in this direction, because everybody suffering from a disease, especially one that affects the brain, would like to have a chance to lead a decent life and not become entirely dependent on another person for care and everyday tasks.

CBD could redeem dignity and self-esteem for people suffering from Parkinson’s, also improving their morale by treating depression, stress, and anxiety. It also allows people to sleep better and be more active, by reducing pain and improving mobility. All these reasons should be good enough in order for more studies to take place in this particular area.
Until an actual cure is found, a treatment that improves life quality will be more than welcome. CBD is entirely safe to be used for medical purposes because it does not have a psychoactive effect. In fact, it helps diminish psychotic episodes, promoting relaxation and a calmer state of mind.
While it may take a while for researchers to fully understand how CBD works in protecting our brain, the positive results speak for themselves and such treatment should be made available as soon as possible.