cbd oil for nausea

Can THC and CBD Really Help with Nausea and Vomiting?

But they’re different. Nausea is an uncomfortable feeling in the upper stomach accompanied by the urge to vomit. Vomiting is the act of throwing up.

Causes of Nausea and Vomiting

There are many causes of why people begin feeling nauseous – pain , stress and anxiety , problems in the digestive system, problems in the middle and inner ear, head injuries affecting the base of the brain and/or the major arteries that supplies this area, and other health conditions.

The regulatory centers for nausea are located in the “Chemoreceptor Trigger Zone” or CTZ found in the medulla—this area is located at the base of the brain.

Drugs, especially those used in chemo, can also induce acute nausea and vomiting because they can stimulate these regulatory centers in the brain as well as irritate the digestive system. Food poisoning, food allergies, and Diabetic ketoacidosis (a life-threatening complication of diabetes) are also other ways to experience acute nausea.

There’s also a conditional called Anticipatory Nausea (ANV) which about a third of chemo patients develop. Anticipatory Nausea can happen a few hours or so prior to a patients chemo treatment which is usually triggered just by the thought of having to get chemo or thinking about taking the medicine.

If a person is undergoing chemo and experiencing severe nausea, they also often have problems with loss of appetite and weight loss.

These symptoms are all problematic for a person who is trying to regain their base level in regards to their health conditions.

So how can you succeed in reducing nausea and control it?

Common Medications for Nausea and Vomiting

There are several different over-the-counter (OTC) drugs for nausea, as well as dietary approaches. These can include eating mild or bland foods, eating smaller meals, eating fennel seeds, or by using OTC drugs like bismuth subsalicylate (i.e. Pepto-Bismol, Kaopectate), or antihistamines.

Prescription medications like ondansetron, hydroxyzine, prochlorperazine or metoclopramide can also be used to as treatments for feeling nauseated.

Side effects vary for each of these medications but are often relatively mild and temporary.

Rare but more serious side effects include dizziness, headache, confusion, increased anxiety, depression, stomach pain, diarrhea, problems with breathing, slurred speech, thirstiness, profuse sweating, vision problems.

However, medications whether OTC or prescription, don’t always work well in individual cases and some side effects can be significant enough that a person can’t take the medication. Cannabinoids may be an alternative solution.

How Cannabinoids Reduce Nausea

There are at least two cannabinoids that may help control feeling nauseous, tetrahydrocannabinol (THC) and cannabidiol (CBD) .

THC appears to help with nausea by stimulating the CB1 receptors in the brain, especially the CB1 receptors found in the regulatory centers for nausea and vomiting. 1 Additionally, THC also stimulates the CB1 receptors in the gastrointestinal tract to reduce intestinal motility. Activating these receptors also improves appetite.

As you may know, recreational cannabis plant users often consume large amounts of food and blame it on the “munchies”. Well, recreation aside, the “munchies” can be a remarkable thing for someone suffering from cancer.

CBD, however, appears to have different actions—it seems to reduce nausea and vomiting by acting on another set of receptors, those that bind serotonin. 1 , 2 CBD, also appears to decrease the release of serotonin, reducing the irritability of the digestive tract and potentially affecting the CTZ.

Synthetic analogs of THC like nabilone (Cesamet) and dronabinol (Marinol) have been used to treat nausea and to increase appetite. 2 Sativex which contains THC and CBD in a 1:1 ratio has also been used to control nausea. 3 CBD oils may also increase the levels of the body’s natural endocannabinoids like anandamide by reducing it’s enzymatic degradation. 4

You should also know, however, that chronic cannabis plant use is associated with something called “Cannabinoid Hyperemesis Syndrome”. 5 It is very rare and is usually associated with cannabis use rather than CBD products. 6

Is CBD Safe?

You might be wondering then, are THC and CBD safe to use for nausea ?

As is very often the case when it comes to THC and CBD, trials are currently in progress, but so far, the data indicates that “Cannabis use appears well tolerated, with few serious adverse effects reported.” 7 Another Phase II clinical study found that THC plus CBD significantly reduced nausea and a persons desire to vomit after chemotherapy and that “most participants preferred cannabis extract to placebo.” 8

CBD alone was studied in rats and was found to significantly reduce vomiting and nausea. 9 In general, CBD oils are considered to be safe and well-tolerated with few significant adverse effects. 10 , 11

Of course, there are precautions in using medical cannabis plants, too, as one study explains and should not be given to vulnerable populations like pregnant women , people with mental illness, adolescents, and people with heart, lungs, and immune system problems. 12

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Which Cannabinoid Works Best for Which Symptom?

Both CBD hemp oil and THC seem to work well to control nausea, but according to the Handbook of Cannabis , written by Roger Pertwee, if you are going to treat nausea alone, Dronabinol (a synthetic THC and approved by the FDA and commonly referred to as Marinol) works best to control mild to moderately-severe chemotherapy-induced nausea.

However, Dronabinol doesn’t seem to work that well in controlling vomiting induced by the stronger chemotherapy drugs. This synthetic THC can also improve appetite and help with weight loss problems. 13 Unfortunately, Dronabinol also has side effects similar to THC. It can produce a “high”, it can cause paranoia, it can trigger mood changes and confusion, and it can increase anxiety.

Plus, Dronabinol can also cause nausea and vomiting, which is frustrating when you think about it because you’re using Dronabinol to control a morning sickness feeling or to prevent nausea in the first place. Using THC alone to control nausea would seem to be counterproductive because of its psychoactive effects.

Finally, you can only use Dronabinol by prescription.

CBD alone can be used—it may take some trial and error to find the best amount for you to take to decrease your nausea and vomiting—the general advice is to start low and go slow.

If you want to try a product with some THC, you can try the full spectrum CBD oil products as they do contain some THC. If you live in a state where both “recreational” and medical cannabis are legal, you can also try to adjust the ratios of CBD and THC—usually between 2:1 CBD:THC and 1:2 CBD:THC. You can also combine these ratios with some dietary approaches—eg, eating blander foods and smaller amounts of food at each sitting.

The best ratio of CBD to THC for nausea may be outside that 2:1 to 1:2 range—you may need to try other combinations to find the best ratio for you. Some people do find that the best approach is the “old-fashioned” one—that is, smoking a joint. Here again, you may have to try different varieties and strains to find your best ratio. There are countless strains from sativa, indica and hybrid cannabis plants.

One advantage is that with the cannabis plant, you can get the most of the entourage effect —the effect that is believed to follow by using the whole leaf.

Best CBD Oil for Nausea

Looking for the best CBD oil for nausea but cannot decide which one to purchase? Check out the following list of reliable CBD products for nausea and see which one is most suited to your needs and lifestyle.

Spruce 750mg Lab Grade CBD Oil
  1. Peppermint flavor masks any unpleasant taste
  2. Contains 25mg of CBD per dropper full
  3. Bottle includes a graduated dropper for correct serving measurement

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Best CBD Purity

NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil
  1. Natural remedy for various illnesses
  2. Product is full-spectrum whole-plant extract
  3. Contains naturally occurring synergistic cannabinoids and terpenes

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Best High Potency

Spruce 2400mg Lab Grade CBD Oil
  1. Maximum possible potency
  2. Each dropper full contains 80mg of CBD
  3. Conveniently fits in a 30mL bottle

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Avida Full Spectrum CBD Oil Tincture 500mg
  1. Proprietary full-spectrum
  2. Developed using advanced AVIDA CORE Spectrum Technology
  3. Highest naturally occurring Phyto-cannabinoids and Terpenes with THC (<0.3)

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cbdMD CBD Oil Tincture Natural 1500mg
  1. made using only CBD sourced from medical hemp
  2. available in many flavours
  3. safe for daily use

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CBDistillery THC Free CBD Oil Tinctures
  1. Do not contain THC
  2. Available in different potencies and sizes
  3. Brand has special deals and offers

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Best Customer Rated

cbdMD CBD Oil Tincture Natural 750mg
  1. THC-free
  2. Has plenty of flavours to choose from
  3. Totally vegan

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Best For Beginners

NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil
  1. Lowest concentration for CBD beginners
  2. Fully organic and lab-tested
  3. Full-spectrum

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Best Flavor Range

Hemp Bombs 750mg CBD Oil
  1. Has a wide range of flavours
  2. Safe to intake
  3. Get 20% off when you avail of their subscription

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Best CBD Oil for Nausea 2022

    Editor’s Pick Best Organic Editor’s Pick Best Seller Best Natural Alternative Best THC-Free Best Customer Rated Best Starter Best Flavor Range

Compare the Best CBD Oil for Nausea in 2022

Best CBD Oil for Nausea

1. Spruce 750mg Lab Grade CBD Oil
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Each bottle of the 750mg CBD oil tincture contains 25mg of CBD per dropper full. The oil is peppermint flavor to mask any unpleasant tastes related to CBD.

2. NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil
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Natural remedy for various illnesses. NuLeaf Naturals’ CBD oil is a whole-plant extract containing a full spectrum of naturally occurring synergistic cannabinoids and terpenes.

3. Spruce 2400mg Lab Grade CBD Oil
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The largest bottle of CBD oil that Spruce offers contains 2,400mg of CBD. This is full-spectrum CBD oil, which is the maximum possible potency. Each high potency dropper full contains 80mg of CBD. There are no flavorings in it, which allows for the most CBD to fit in the 30ml bottle.

4. Avida Full Spectrum CBD Oil Tincture 500mg
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Avida Extracts Full Spectrum CBD oil is the latest iteration of the brand’s advanced Avida CORE Spectrum technology. They use a proprietary full spectrum blend, resulting in the highest naturally occurring Phyto-cannabinoids and Terpenes with THC (<0.3) to support your health.

5. cbdMD CBD Oil Tincture Natural 1500mg
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cbdMD’s CBD oil tinctures are made using only CBD sourced from medical hemp and MCT oil as a carrier oil. Tinctures are offered in orange, mint, natural, and berry flavors. Safe for daily use, the oil tinctures are packaged with a built-in rubber dropper to adjust CBD dosage easily. The packaging is made to be easy to transport and discreet to use.

6. CBDistillery THC Free CBD Oil Tinctures
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CBDistillery’s Isolate CBD Oil Tinctures harness the power of pure CBD. CBD Isolate Oil Tinctures include 0.0% THC. When you use CBDistillery CBD Isolate Oil Tinctures, you can be assured you’re using the highest quality CBD on the market.

7. NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil
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This is one of several concentrations from NuLeaf Naturals. As the lowest concentration, it is the company’s best option for those new to CBD oil. The product is lab-tested and fully organic. It is full-spectrum, so it contains THC in small quantities.

8. cbdMD CBD Oil Tincture Natural 750mg
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A 750mg bottle of cbdMD’s Broad Spectrum Oil Tincture does not contain THC. It also has a fairly wide flavor range which is perfect for those who prefer other taste. Vegan consumers are considered since cbdMD offers Vegan products. Aside from all of that, another reason why people love cbdMD is because it’s free from harmful chemicals.

9. Hemp Bombs 750mg CBD Oil
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Hemp Bombs offer CBD Oil Tinctures that come in a 30ml bottle containing 750mg of CBD. They provide a wide range of flavors perfect for those that have a knack for sweets. Consumers can safely intake this because it’s free of chemicals and pesticides. Hemp Bombs also offer a 20% off on products upon subscription.

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Benefits of CBD for Nausea

Nausea is a protective defense mechanism of the human body . Common causes of nausea include migraine attacks, appendicitis, gastroenteritis, motion sickness , food poisoning , dizziness, morning sickness , chemotherapy, and brain tumor (1) .

While different antiemetic drugs may help reduce nausea, many of them cause adverse effects (2) .

Common side effects include headache, dizziness, drowsiness, constipation , vision changes, and sedation. Antiemetic medicine may also cause vertigo, low blood pressure, and dysphoria.

The most serious and worrisome side effect of antiemetic drugs is QT prolongation. QT prolongation means that the heart muscle recharges longer between beats.

QT prolongation has been associated with an increased risk of life‐threatening ventricular arrhythmia and sudden cardiac death (3) .

Thus, more people become interested in natural and safe alternatives for nausea, like CBD .

Research has indicated CBD’s potential benefits in treating nausea. A 2002 study published in Neuroreport highlighted CBD as a non-psychoactive compound that may interfere with nausea in rats (4) .

Results suggested that CBD and other non-psychoactive compounds may help treat chemotherapy-induced nausea.

A study performed in 2003 examined the effects of cannabinoids in rat models of nausea. Rodents were given cannabinoid agents, like tetrahydrocannabinol (THC) and HU-210, and results revealed that CBD may suppress nausea (5) .

Although these studies are conducted on animals, future research may find similar benefits of CBD for nausea in human subjects.

A 2011 study published in the British Journal of Pharmacology showed that CBD may also suppress nausea and vomiting (6) . The research noted t hat CBD may effectively treat nausea and vomiting produced by chemotherapy or other treatments.

A 2017 review on the therapeutic effects of cannabis showed that cannabinoids or naturally occurring compounds may cause anti-nausea effects for adults experiencing chemotherapy-induced nausea and vomiting (7) .

The literature did not specifically show CBD’s effectiveness in chemotherapy-induced nausea, nor its potential as an effective treatment for nausea.

However, a review on cannabinoid regulation of acute and anticipatory nausea suggested CBD as a potential anti-nausea agent (8) .

Meanwhile, the Food and Drug Administration ( FDA ) has approved the use of dronabinol and nabilone (synthetic tetrahydrocannabinol ) to treat chemotherapy-induced nausea and vomiting (9) .

Epidiolex is the first FDA -approved CBD drug to treat seizures associated with Lennox-Gastaut Syndrome and Dravet Syndrome, two rare cases of childhood epilepsy.

There is an increasing demand for non- FDA approved indications. Thus, independent companies have produced different CBD oil products to satisfy the public’s needs.

How CBD Oil Helps With Nausea

CBD, a cannabinoid or naturally occurring compound in cannabis plants , may be beneficial for nausea through its interaction with the endocannabinoid system ( ECS ).

The ECS maintains homeostasis or balance in biological functions, including mood regulation, pain perception, and immune response (10) .

The ECS also has two main types of cannabinoid receptors : CB1 receptors and CB2 receptors . Located on cells throughout the body, these receptors interact with cannabinoids or compounds in the body.

CB1 receptors lie in the brain and central nervous system . They regulate bodily functions, such as memory processing, appetite, pain sensation, mood, and sleep.

CB2 receptors lie in cells within the immune system and its linked structures. Once activated, these receptors stimulate a response that helps fight inflammation.

A study highlighted CBD’s potential anti-inflammatory and analgesic effects by promoting the signaling of the adenosine receptor A2A, which helps suppress immune cells (11) . Thus, CBD may relieve nausea and settle an upset stomach and other related symptoms.

Moreover, the human body naturally produces cannabinoids or endocannabinoids, like anandamide. A 2013 study showed that anandamide may regulate toxin-induced nausea and vomiting (12) .

However, fatty acid amide hydrolase (FAAH) is responsible for the degradation of anandamide (13) . As CBD oil inhibits FAAH, it may slow down anandamide’s decomposition, helping relieve nausea (14) .

A 2012 study also emphasized cannabidiol ’s potential ability to trigger the ECS to produce more anandamide (15) .

Furthermore, a 2011 study showed that CBD may produce anti-nausea effects through the indirect activation of 5-HT1A serotonin receptors (16) . The “happy chemical” serotonin plays a crucial role in mood, anxiety levels, appetite, and cognitive functions.

CBDA (the acidic raw form of CBD ) is even more active at binding to serotonin receptors and may be a potent antiemetic (17) .

Thus, the studies mentioned above suggest that CBD may provide health benefits for chemotherapy-induced nausea and vomiting and other related conditions.

How Soon Can CBD’s Effects Be Felt?

CBD’s potential benefits in nausea may take effect faster or last longer depending on different factors, including t he administration method, body weight, metabolism, and CBD potency.

CBD oil tinctures are one of the fastest ways for CBD to get into the body as it is a bsorbed directly into the bloodstream. Results may be experienced within 30 to 60 minutes.

CBD oil vapes also produce one of the fastest effects of CBD as the compound enters the bloodstream through the lungs. Results may be felt within 20 minutes.

Meanwhile, CBD edibles may take longer to work as CBD has to pass through the digestive system . The effects of CBD edibles, like gummies , may kick in within 30 to 60 minutes (18) .

How long CBD’s potential therapeutic benefits for nausea will remain or continue may depend on the form of CBD used.

While CBD tinctures may provide immediate relief, effects may last for four to six hours only.

Meanwhile, CBD edibles’ effects may last for over six hours (19) . For CBD vapes , results may last for 30 minutes or an hour or two only.

Other factors, like metabolism, frequency of use, dosage, and product quality, affect how long CBD helps with nausea.

Possible Side effects of Using CBD for Nausea

  • Dry mouth
  • Diarrhea
  • Drowsiness
  • Reduced appetite
  • Tiredness
  • Fatigue
  • Changes in weight

CBD may also interact with some medications, such as blood thinners.

According to a 2011 review, CBD may induce side effects , such as the inhibition of hepatic drug metabolism, decreased fertilization capacity, and decreased activities of p-glycoprotein and other drug transporters (21) .

CBD Dosage for Nausea

CBD dosage of up to 1,500 mg/day is well tolerated in humans (22) .

However, Epidiolex is the only FDA -approved CBD product with a recommended starting dosage of 2.5 mg/kg taken twice a day (23) . Other than this, there is no official recommended CBD dosage for nausea.

Moreover, determining the right CBD dosage is challenging, as effects also vary depending on several factors. These include body weight, metabolism, CBD potency, and product quality.

Thus, users are advised to start taking CBD in small doses , around 5mg. Once they experience relief from nausea, they can gradually increase the dosage.

Consumers should also consult a healthcare professional, especially one knowledgeable about cannabis use, to help them determine the right dosage of CBD based on their needs and preferences.

How to Take CBD Oil for Nausea

The increasing popularity of CBD as an alternative treatment for different medical conditions urges companies to produce various CBD oil products.

The most common types of CBD products for nausea include CBD tinctures , CBD capsules, CBD edibles, and CBD vapes . They are available in various CBD retail stores, dispensaries, or online.

CBD Oil Tinctures

CBD tinctures are the most common form of CBD product . Users can easily apply CBD tinctures sublingually or directly under the tongue to facilitate faster absorption of CBD directly into the bloodstream.

Consumers can let the desired quantity of drops stay under the tongue for 60 seconds before swallowing . Depending on the metabolism and other significant factors, results may show within 30 minutes to 60 minutes.

Generally, the effects may also last for four to six hours. One drawback, however, is the earthy taste of CBD oil .

Fortunately, other CBD brands offer CBD tinctures in different flavors. However, users should be cautious of artificial flavors and ingredients added to CBD products .

CBD tinctures may also be used with CBD lotions and creams and applied transdermally for site-specific pain relief.

An animal study showed that CBD topicals may reduce inflammation and arthritis-pain related symptoms without evident side effects (24) .

CBD Oil Edibles

CBD edibles, like gummies , are perfect for those who do not want the earthy flavor of CBD. However, unlike CBD oral products, CBD edibles can take a while to work as they need to pass through the digestive tract.

According to a 2016 study, CBD edibles’ effects may be felt within 30 to 60 minutes (25) . CBD edibles that contain THC , peak blood levels occur approximately three hours later, and the effects can last over six hours.

CBD Oil Capsules

Another convenient way to take CBD oil is through CBD capsules. However, like CBD gummies , CBD capsules may take longer to work than oral CBD drops as they need to go through the digestive system .

Thus, CBD capsules may not be suitable for those needing immediate relief from nausea.

However, CBD capsules are recommended for those who want a tasteless CBD experience.

CBD Oil Vapes

CBD oil vapes provide the fastest ways to get CBD into the system, as the vapors enter the bloodstream through the lungs without going through the digestive system .

However, effects may last for 30 minutes to an hour or two only. It is also difficult to determine precisely how much CBD is in each draw.

While CBD oil vape products usually indicate the CBD amount per inhale, the amount may vary per individual.

Furthermore, the FDA, Centers for Disease Control and Prevention, and other state and local health departments have conducted investigations regarding a national outbreak of e-cigarette or vaping product use-associated lung injury (EVALI) (26) .

As of February 18, 2020, there were 2,807 hospitalized EVALI cases or deaths reported to CDC. Thus, the CDC and FDA do not recommend using vapes .

How to Buy the Best CBD Products for Nausea

  1. Seek medical advice, especially if purchasing CBD products for the first time or taking other medications to ensure proper CBD use.
  2. Check whether the CBD product uses non-GMO, organic hemp. Also, choose quality products that use CO2 extraction techniques to maximize the benefits of hemp extracts .
  3. Verify whether the product undergoes third-party lab testing. The certificate of analysis (COA), often available on the brand’s website, must indicate the product’s actual CBD content and absence of pesticides , residual solvents , and other harmful contaminants.
  4. Compare product label claims and the COA. Third-party testing of high-quality CBD hemp oil products shows accurate or higher CBD content than their product label claims.
  5. Know the different CBD types: full-spectrum CBD, broad-spectrum CBD, and CBD isolates.

Full-spectrum CBD products have a complete range of cannabinoids or naturally occurring compounds in cannabis plants, including CBD, THC, terpenes, flavonoids, fatty acids, and other minerals.

Terpenes provide cannabis plants’ unique aroma, while flavonoids are responsible for their vivid colors.

These compounds produce the “entourage effect,” which means they provide more benefits when combined than when they are used as isolated elements (27) . Thus, full-spectrum CBD oil suits users who want to maximize all compounds’ benefits.

Meanwhile, broad-spectrum CBD also contains all compounds in cannabis plants, except THC. Consumers who do not want to experience the euphoric effects of THC may use broad-spectrum CBD.

However, users may also choose CBD isolates, which are pure CBD extracted in isolation from all other compounds.

Legality of CBD

Cannabis laws continuously change, especially in the United States. Following the 2018 Farm Bill, industrial hemp became legal, which means that hemp-derived CBD products with 0.3% or less THC are no longer considered controlled substances under federal law (28) .

Tetrahydrocannabinol is a psychoactive compound that causes a euphoric high among users. Marijuana remains a Schedule 1 controlled drug given its high potential for abuse, attributable to THC ’s psychoactive effects (29) .

However, the 2018 Farm Bill preserved the FDA ’s authority to regulate products containing cannabis or cannabis -derived compounds.

According to the FDA , products with THC or CBD should not be sold legally as dietary supplements. Currently, the FDA approves only one cannabis-derived drug product, Epidiolex (cannabidiol), and three synthetic cannabis-related drug products: Marinol (dronabinol), Syndros (dronabinol), and Cesamet (nabilone) (30) .

Epidiolex is a purified form of CBD derived from cannabis , approved to help treat seizures associated with Lennox-Gastaut syndrome and Dravet syndrome, two severe kinds of epilepsy in children.

Meanwhile, Marinol and Syndros are approved to treat anorexia associated with weight loss in patients with acquired immunodeficiency syndrome (AIDS).

Cesamet is used to reduce nausea associated with cancer chemotherapy.

Given that no other FDA -approved CBD products are available, consumers must buy CBD in states that allow recreational or medical marijuana use.

Product Frequently
Asked Questions

CBD may help with nausea through its interaction with the endocannabinoid system , which maintains balance in various bodily functions, like pain perception and immune response (31) .

CBD may also help activate serotonin receptors (32) . Serotonin helps regulate mood, anxiety levels, appetite, and cognitive functions.

Research has shown that CBD may suppress nausea in cancer patients undergoing chemotherapy and other therapeutic treatments (33) .

While research on CBD’s effectiveness for nausea remains inconclusive, no study has shown that CBD can make nausea worse. Current evidence suggests CBD’s benefits in relieving nausea from cancer treatment (34) .

CBD may interact with other drugs for nausea, altering how the body breaks down other medications (35) . Thus, users should seek medical advice to ensure proper CBD use and dosage.

Studies have shown that CBD may help with nausea when used alone or with conventional antiemetic drugs (36) . However, results from clinical trials are still inconclusive, so users should seek medical advice before using CBD for nausea, especially when taking other medications.

CBD is a non-psychoactive component of cannabis that will not get you high or make you fail a drug test (37) . However, full-spectrum CBD products may contain small amounts of the psychoactive compound, THC . Frequent usage of these products may result in a false-positive drug test.

There are no official guidelines regarding the recommended dosage for nausea. However, it is best to start at low doses and increase dosage once relief from nausea is experienced. Results also depend on various factors, like metabolism, CBD concentration, and product quality.

The most common way to take CBD oil for nausea is through CBD tinctures , which allow direct absorption of CBD into the bloodstream.

However, the best way to take CBD depends on the consumer’s wants and needs. Thus, users can also take CBD edibles and capsules if they want to avoid the grassy, earthy flavor of hemp plants .

CBD is generally safe and well tolerated by humans (38) . Minor side effects may include drowsiness, diarrhea, dry mouth , and fatigue (39) .

Best CBD oils for nausea: Top brands in 2021

Nausea is a stomach uneasiness that normally occurs before vomiting. The discomfort usually includes symptoms such as lightheadedness, vomiting, headache, diarrhea, and fever among others.

While nausea can be managed by OTC drugs, a lot of people have reported massive side effects of these drugs. So, they are turning to alternative sources of medicine such as CBD. In this article, we are going to review the best CBD oils for nausea and key factors which you must consider when buying CBD oil products.

Managing nausea with cannabis

Nausea usually occurs as a defense reaction. The body is usually trying to warn you about the consumption of harmful substances. Even though this is a common occurrence, it’s not possible to outrightly identify what normally triggers nausea.

There are many anti-nausea medications available in the market. While some are highly effective, there are medications that cause unwanted side effects. Some of the possible reactions that you might experience include headaches, change in vision, drowsiness, and sometimes abnormal heart rhythms.

Generally, the consequences of using anti-emetic drugs can be far worse than nausea itself. That’s why a lot of people are turning to alternative medications such as CBD to treat nausea. CBD is an effective natural remedy that works with the endocannabinoid system to improve general wellness. It has anti-nausea and anti-emetic effects that work efficiently.

Studies on how CBD oil works for nausea

There is a lot of research ongoing about CBD and how it can help in managing conditions such as nausea. Preliminary reports from animal studies indicate that CBD is effective in minimizing the symptoms of nausea since it normally interacts with the endocannabinoid system.

It should be noted that the endocannabinoid system is responsible for homeostasis. This includes promoting the optimal functions of hormones and how the body handles its processes. When CBD interacts with this system, it’s said that it promotes its effectiveness.

When it comes to nausea, CBD normally interacts with serotonin receptors. Well, this is the hormone that influences how you feel, for instance, your mood or even the general sense of your wellbeing.

If you become nauseated, then serotonin receptors are part of the reason. When the levels of these receptors are high, they end up pushing out noxious or they upset the food more quickly in your diarrhea. As a result, the chemical increases in your blood and this stimulates the brain part that’s responsible for controlling nausea.

CBD helps to regulate the production of serotonin and reduce its high level. This consequentially has a direct impact on the symptoms of nausea.

Furthermore, human studies have established that a combination of CBD and THC is even more effective in relieving nausea. THC is the main psychoactive compound in cannabis plants. It’s highly effective when it comes to significantly reducing the symptoms of nausea and vomiting.

CBD oil for nausea: use and benefits

Using CBD oil for nausea is a straightforward process. Depending on the dosage and flavor, you can take the oil drops orally, as tinctures. Place a few oil drops under your tongue and wait for a couple of minutes before swallowing or spitting the oil.

Secondly, you can put the oil drops in your favorite food or drink and then consume it. For long-term use, some people even use the oil with some baked edibles such as bread. The benefits of CBD in dealing with nausea include influencing how your hormone works and promoting a general sense of good wellbeing.

Other benefits of using CBD include:

  • Non-intoxicating benefits since cannabidiol don’t have psychoactive effects
  • You can use CBD to manage long-term symptoms of nausea since it’s non-addictive. Several research studies show that it’s potentially the best alternative source of medicine that’s suitable for long-term use.
  • The natural treatment option has minimal severe side effects unlike most clinical medications

What to look out for when selecting the best CBD oil for nausea

There are already many brands that sell CBD oil products. With the medical marijuana market being widely unregulated, finding the best CBD oil for nausea isn’t a walk in the pack. New brands are always coming with CBD hemp oil for nausea and if you are not keen you may end up with a low-quality product.

To ensure that you pick the best products for the management of nausea, here are some of the factors that you need to consider.

1) The source of hemp

We mainly considered brands that sourced their hemp plants domestically. Besides that, we also prioritized hemp plants that were organically cultivated. Hemp plants are bioaccumulators and they normally absorb anything in their surroundings. It’s important that they are cultivated in a pesticide- and chemical-free environment for the safety of the consumer.

2) Method of extraction

Extracting high-quality and contaminant-free CBD oil is very expensive. That’s why brands sometimes opt for cheap methods. However, these cheap methods usually lead to the production of low-quality products. The industry standard at the moment is the use of CO2 extraction. Products manufactured with the use of this method are usually of high-quality.

3) Product potencies

When managing medical conditions such as nausea and vomiting, there are different levels of intensity. Severe medical conditions require more potent CBD products. The converse is also true. One of our main concerns was brands that sell products with multiple potencies. This is important as it helps to ensure that customers have multiple options to choose from.

4) Certificate of analysis

This is an important document, especially in matters of quality assurance. While there isn’t a specific regulatory body for medical cannabis products, there are brands that normally use independent 3 rd -parties to test their products. These are the brands that we considered since their products are more likely to be of high-quality.

The best CBD oil brands for nausea

Your nausea can be effectively handled if you find the best CBD oil. But as the market is filled with a wide range of products to choose from, the selection process can be quite difficult.

However, you don’t have to go through the grueling process of comparing several products – this article does it for you. Here is a review of five of the top CBD oil products that are ideal in managing the symptoms of nausea.

1) Fab CBD

Fab CBD was formally established in 2017. It’s one of the top-rated brands with the best CBD oil for nausea. It’s known for selling high-quality CBD oil products that enhance general wellness.

What’s good about it?

  • Multiple potency options ranging between 150 mg and 2400 mg
  • You can find the CBD oil in multiple flavors
  • Each product batch normally undergoes independent 3rd-party tests

What’s not so good: The CBD oil products usually sell fast

This is the number one brand with the most premium CBD oil. Fab CBD normally sources its hemp extracts domestically. Besides that, the brand normally uses a premium extraction method to ensure that you end up with a high-quality product.

If you are dealing with mild or severe cases of nausea, Fab CBD has oils of different potencies for easy adaptation. They range between 150 mg and 2400 mg. besides that, the CBD oil products are available in flavors such as natural, berry, citrus, and vanilla. This way, you can conveniently choose a product depending on your taste preferences.

For consistency and efficiency, each of the product batch has to undergo independent third-party tests. Fab CBD usually avails this information on its official website. So, you can check and verify information such as CBD content and other contaminants.

2) Spruce CBD

Spruce is a family-based brand that manufactures effective CDB oil. The lab-tested and organic full-spectrum CBD oil products are usually made using some of the finest and oldest hemp strains in the US. First established in 2018, this brand prides itself in making unique American-based CBD oil.

What’s good about it

  • Organic CBD oil that’s contaminant-free
  • Full-spectrum and highly potent CBD oil

What’s not so good: Limited product variety

The first thing you will notice once you open Spruce’s website is the organic nature of its CBD oil products. They are made with 100% natural plant extracts. It’s worth noting that hemp plants are usually cultivated in environmentally-friendly farms with no pesticides.

To ensure that the CBD oil products are of lab-grade quality, Spruce normally uses the moonshine/alcohol extraction method. This usually results in a hemp-rich extract that’s safe and effective for use in managing your nausea. You can get the CBD oil in two potencies i.e. 750 mg and 2400 mg.

3) Joy Organics

Joy Organics is renowned for specializing in manufacturing broad-spectrum CBD products. Their CBD oil contains all the beneficial components found in hemp extracts. In case you are keen on using THC-free CBD oil that’s THC-free, then this is the best brand to choose from.

What’s good about it

  • Non-GMO and gluten-free CBD oil
  • THC-free and broad-spectrum
  • Multiple potencies to choose from

What’s not so good: The levels of cannabinoids are quite low

Joy Organics CBD oil products have the highest level of bioavailability. Well, this is because this brand uses nanotechnology to generate its CBD hemp oil. This is an effective technology that allows the cannabinoid molecule to be significantly broken down into smaller sizes.

It should be noted that most CBD oils have particles measuring between 150 and 500 nanometers. Meanwhile, Joy Organics CBD oil particles measure 25 and 60 nanometers.

To ensure that you get quality CBD oil, Joy Organics uses its proprietary extraction method that normally produces 112 minor cannabinoids. This broad-spectrum CBD oil contains all the vital plant components such as cannabinoids, flavonoids, and terpenes.

The brand normally subjects its products to independent third-party tests. You can find the comprehensive report in the form of the Certificate of Quality Assurance and Certificate of Analysis. The combination of both in-house and third-party lab tests helps to ensure that the CBD oil remains free of toxic metals and harsh chemicals.

4) CBDfx

CBDfx is a relatively new innovative company that was first established in 2015. It has a wide range of CBD oil products designed to improve general wellness.

What’s good about it

  • Potent CBD oil products
  • All products are subjected to independent 3rd-party lab tests
  • The CBD oil is available in multiple potencies

What’s not so good: It’s not easy to find the right information

CBDfx thrives by producing some of the best hemp-based products in the world. The brand has the best CBD oil for nausea, especially when it comes to product variety.

For starters, CBDfx usually sells fully organic products. It normally sources its products domestically from farms in Kentucky. The hemp plants are normally cultivated organically using environmentally-friendly farming practices.

Besides that, the refinery process is usually comprehensive and it involves the use of premium CO2 extraction. This guarantees users the most refined products that are contaminant-free. It should be noted that CO2 extraction is currently the industry standard since it produces quality and highly effective CBD oil.

To ensure that you fully deal with your symptoms of anxiety, CBDfx uses full-spectrum CBD oil. This means that your body is guaranteed the entourage effect. Consequentially, you will experience heightened response and improved general well-being.

Apart from the CBD content, CBDfx CBD oil for nausea is rich in cannabinoids, terpenes, and flavonoids. There is also a trace amount of THC-content for more potent action.

Overall, CBDfx has a diverse product line. As a result, you can choose from the multiple potency options available depending on your budget and needs.

5) Purekana

Purekana only sells verified high-quality CBD products. It was established in2017 and has quickly grown to become one of the top companies in the US.

What’s good about it

  • Pure and organic CBD oil products
  • Effective in promoting general wellness
  • Ideal for long-lasting use
  • Multiple flavors to choose from

What’s not so good: The CBD oil is quite expensive

Purekana CBD oil for nausea is designed to improve vitality. The brand uses domestically-sourced hemp plant extracts that are fully organic. Besides that, it uses premium CBD oil extraction to ensure that the end product is of high quality and with high levels of safety.

What makes PureKana stand out is that there is a wide range of products to choose from. For instance, you can pick from flavor options such as natural, mint, and vanilla. The flavors are available in several potency options including 300 mg, 600 mg, 1000mg, 2500 mg, and 5000 mg.

This way, you can conveniently pick a product depending on the severity of your medical conditions. If you have mild or moderate nausea symptoms, then the 300 mg or 600 mg CBD oil products are the most ideal. Severe conditions require more potent products such as 1000 mg or 2500 mg.

For effectiveness and consistency in quality management, this brand normally subjects all its products to independent 3rd-party lab tests. Purekana normally uses Ace Analytics lab that’s based in California. The products are not only tested for CBD content but also pesticides, microbes, as well as heavy metals.

How to choose the best CBD oil for nausea

The effectiveness of CBD oil in managing nausea can’t be ignored. You can use full-spectrum, broad-spectrum, or isolate CBD. All these products contain cannabidiol as the main active ingredient. This organic chemical compound has natural healing properties that work with the body to improve wellness.

But what should you consider when buying CBD oil for nausea? With the broad range of CBD products in the market, you need to be very careful. Here are some of the factors that you need to consider include.

1) The different types of CBD product

There are three main types of CBD oil products that you can choose from. Isolate CBD contains more than 99% CBD compound. It’s ideal for those who want to completely avoid other cannabinoids.

Broad-spectrum CBD has cannabidiol in addition to other plant compounds such as terpenes and flavonoids. However, it doesn’t contain THC content even though it normally produces the entourage effect. Lastly, full-spectrum CBD has cannabidiol and other cannabinoids including trace THC content. This type of CBD oil is considered to be the most potent thanks to its ability to produce the entourage effect.

2) The type of brand

There is a wide range of CBD oil brands in the market. Due to the lack of a specific regulatory body, it’s easy to buy a low-quality product from illegitimate brands.

If you want to buy high-quality CBD oil, consider the legitimacy and reliability of the brand. Check for the company’s web profile and physical address. Is it a registered company? Can you physically find its official offices? Do they have working contact information?

3) Check for customer reviews

When researching the best CBD oil for nausea, do a comprehensive analysis of the customer reviews. Check the company’s official website and analyze different product reviews. If the CBD oil is effective, it will have a higher star rating due to numerous positive customer reviews. On the other hand, products with low star ratings aren’t highly effective due to bad customer reviews.

4) Certificate of analysis

The most reputable brands that want to produce quality CBD products usually carry out independent 3 rd -party lab tests. Since this market isn’t widely regulated, serious brands have taken the initiative to verify the effectiveness of their CBD oil products.

So, if you are keen on buying quality CBD oil products, check for the certificate of analysis from the brand’s official website. It should be readily available and contain the latest updated certification results. Additionally, the screening should be thorough and include information such as CBD content, availability of contaminants, and other toxic elements.

Note: When checking the third-party lab results, compare the information on the product label and the contents found in the certificate of analysis. The company claims should be able to match the information from the certification authorities.

5) Multiple product options

You need to choose a CBD product that suits your needs as well as the severity of your medical condition. The best CBD oil brands usually offer multiple strength options to choose from. Additionally, they also offer CBD oil products in different flavors.

What are the side effects of CBD oil?

Using CBD oil seems to have lots of benefits. But while this organic product has a good safety profile, it can also carry some serious risks. It’s true that CBD oil is well-tolerated but its potential side effects include:

  • Drowsiness
  • Dry mouth
  • Abdominal discomfort
  • Reduced appetite
  • Change in weight
  • Fatigue
  • Change in sleep patterns

Note: CBD can also interact with some medications, for instance, blood thinners. So, if you are taking prescription medication, first talk to your doctor first.

CBD dosage for nausea

It’s not easy to determine the most effective CBD oil dosage for nausea. This is because there are several guidelines that affect the dosage. They include the severity of your condition, your age, sex, rate of metabolism, and weight.

However, weight is the most commonly used factor that’s used to determine dosage. Below is an overview of the recommended CBD dosage.

Weight Mild Effects Moderate Effects Strong Effects
5-11 St. 12 mg 18 mg 22.5 mg
11-17 st. 15 mg 22.5 mg 30 mg
17 st. 18 mg 27 mg 45 mg

Can you give your dog CBD oil for car sickness?

Humans normally use CBD oil to manage their nausea. Dogs are just like humans and they also have the endocannabinoid system. Besides that, research studies show that CBD can be highly beneficial when dealing with nausea caused by motion sickness.

For effective results, it’s advisable that you give your doctor the product earlier before the start of the journey. This way, the effects of CBD will start before the symptoms escalate.

Can CBD oil help you with your nausea?

You can use CBD drops for nausea to manage the feeling of discomfort that comes before vomiting. The above-reviewed CBD products have proved to be effective in regulating the activities of the serotonin hormone.

They come in different concentrations and flavors to cater to different user needs. But before using CBD hemp oil for nausea, make sure that you first consult your doctor.