CBD Oil for Weight Loss
CBD oil is making a name for itself in a big way these days. Whether it’s to combat stress, help with sleep, or relieve pain, you’ve undoubtedly come across someone who swears by CBD. And now, there’s talk that CBD oil may even help with weight loss.
According to preliminary research, CBD may reduce food intake and boost metabolism, which could ultimately promote weight loss. This is surprising for many to hear, since most assume that cannabis derivatives actually stimulate hunger. However, CBD is very different from its psychoactive cousin, THC – the compound responsible for marijuana’s psychoactive effects.
CBD is non-psychoactive and has completely different effects on things like metabolism and appetite – both of which play a major role in the body’s inclination to either lose or gain weight.
In this article, we look at the existing research on using CBD oil for weight loss, as well as the specific ways in which it may be effective.
What Role Does the Endocannabinoid System Play?
As always, the effects of CBD are linked to the Endocannabinoid System (ECS). The ECS is what helps cannabinoids, like CBD and THC, interact with the body.
When it comes to the ECS and weight loss, our metabolism is a key player. The ECS is directly linked to energy storage and nutrients transportation and thereby helps regulate everything from sleep and mood to inflammation and temperature. Additionally, a study from 2008 reported that the ECS is responsible for stimulating areas of the body involved in metabolism, such as the pancreas and gastrointestinal tract.
From a scientific viewpoint, the ECS is composed of metabolic enzymes that interact with various parts of the body. There are two endogenous compounds through which it does this – anandamide and 2-AG (2-arachidonoylglycerol). Both of these target CB1 and CB2 receptors found throughout the body. Since cannabinoids like THC and CBD also interact with these receptors, it seems likely that CBD oil may be able to help with metabolism and/or weight loss in some way.
4 Ways CBD May Help With Weight Loss
Here are a few of the ways in which CBD oil may be effective in helping with weight loss.
CBD and Fat Browning
According to a 2016 study published in the journal Molecular and Cellular Biochemistry, CBD is capable of converting white-colored fat tissue (responsible for storing energy) into beige-colored fat tissue (responsible for burning it). In other words, it turns the harmful white fat associated with diabetes and obesity into hard-working brown fat cells. This process is sometimes referred to as “browning and results in:
- Enhanced ability of the body to burn calories
- Enhanced breakdown and oxidation of fat
- Decrease in the expression of proteins involved in creating new fat cells
Most people associate cannabis with an increase in appetite, as many people seem to suffer a case of the “munchies” after smoking marijuana. In fact, some doctors even prescribe medical marijuana to chemotherapy patients in an effort to boost their appetite. However, this has got to do with the amount of THC present in a strain.
While both THC and CBD come from the cannabis plant, they’re very different compounds with different effects. A 2017 study in the Netherlands gave people different strains of cannabis to try. They found that those who got the strain with the highest CBD content had their appetite increase the least, compared to the others who had the THC-only strain.
Moreover, a 2012 study done on rats reported that CBD was likely to reduce food intake. Ultimately, CBD is believed to be more of an appetite suppressant.
The liver is responsible for removing toxins and converting excess sugar into insulin. Insulin is a hormone released by the pancreas and into the cells, where it’s then converted into energy.
After many years of eating high sugar foods, insulin levels gradually rise. The problem is that irregular insulin levels can overload the pancreas and liver, throwing the body for a loop. Additionally, whenever insulin levels are high in the bloodstream, the body is unable to burn fat. As a result, shedding weight can be quite a struggle.
According to a preclinical study done in 2006, CBD has the ability to lower instances of diabetes in non-diabetic mice. Based on this finding, it’s been deduced that CBD has the potential to stabilize insulin levels and, therefore, may be effective for weight loss.
However, aside from this, the relationship between insulin regulation and CBD is not well-studied.
CBD and Exercise
Lastly, CBD is also believed to help people stay focused and energized. As reported in a 2014 research review, CBD may promote wakefulness for some people, although researchers did note that further research on the subject was needed.
But based on this finding, it’s been suggested that CBD could give those on a weight loss journey the focus and energy needed to exercise, especially if they’ve been feeling reluctant to do so. In other words, CBD could indirectly help with weight loss through its ability to enhance a person’s willingness to get active.
CBD for Weight Loss: Risks and Considerations
Although preliminary results from studies on CBD and weight loss are promising, there are a few important things to consider.
Firstly, CBD oil is in no way a treatment for obesity. It’s not a one-size-fits-all solution for weight loss and should not be used as a replacement for a healthy diet and regular exercise. A person who adds CBD oil to their weight loss plan without also following a healthy diet and exercising may not see any positive impact.
It’s best to work directly with a physician when using CBD oil for weight loss. Doctors will advise on dietary requirements, as well as other healthful activities to implement. They can also discuss whether CBD would make for a good addition to a person’s wellness regime.
Final Thoughts on Using CBD Oil for Weight Loss
It’s important that you don’t see supplementing CBD oil for weight loss as a way to avoid getting active and eating well. Research on CBD is still in its infancy, and studies done on CBD and weight loss are very limited.
That said, research thus far has been promising and definitely seems to suggest that CBD may make for a great addition to one’s overall health and wellness regime. The Premium Jane CBD oils are some of the best on the market and a great place to start for anyone interested in adding CBD to their health supplement collection.
Your CBD launches oil targeting weight loss without side effects
04 Oct 2021 — US-based retailer Your CBD has unveiled a cannabidiol (CBD) product targeted at weight loss. The innovation comes following two decades of global research.
The product, called Trim by Sunmed, is backed by a “first-of-its-kind” human clinical study, which showed the core component of the product tetrahydrocannabivarin (THCV) suppressed the natural appetite of participants, according to the retailer.
“We believe that Trim by Sunmed fills a major void that has existed in the marketplace, using natural weight loss remedies as opposed to harsh stimulants, allowing hemp to do the work,” states Marcus Quinn, founder of Your CBD.
The product is available as a tincture or soft gel capsule. Hemp over stimulants
Trim aims to utilize hemp as a natural alternative to aid weight loss, arguing that in contrast to other cannabis products that heighten cravings, the THC-V component targets receptors in the brain associated with cravings and lets the body know that it is satiated.
The retailer notes that using CBD oil allows individuals to escape adverse side effects caused by many traditional weight loss supplements such as rapid heart rate, jitters and headaches.
The study, which spanned over 13 weeks, found that Trim by Sunmed utilizes therapeutic naturally derived cannabinoids that antagonize the CB-1 receptor and suppress cravings, it adds.
A wide array of benefits
In addition to being a natural weight-loss alternative, Trim by Sunmed also boasts benefits such as improved sleep, reduced anxiety and pain relief, according to Your CBD.
“This natural approach to weight loss has many added benefits such as anti-inflammation, deeper and longer sleep, as well as a reduction in pain, depression and anxiety,” says Dr. Anthony Ferrari, chief science officer of Your CBD.
Easy to use
Trim can be consumed either through a tincture or a soft gel capsule and should be incorporated into daily routine, including a healthy diet and active lifestyle. It can also boost the effectiveness of exercise and nutrition, without any extreme adjustments, the retailer affirms.
The recommended serving is 50 mg per day over a 90-day introductory period. Within that time frame, clinical trials have shown up to 18 lbs in weight reduction and up to six inches in waistline reduction resulting from consistent use of Trim by Sunmed.
The product is sold at an introductory price of US$100 at Your CBD Store locations. Products are made using US-grown hemp.
Defining the era of CBD Clinical studies have shown that the product suppresses cravings and thus aids weight loss.
Consumers are turning more toward CBD products for natural solutions, particularly since the US Food and Drug Administration (FDA) softened its stance in 2018, allowing progressive regulatory gains since the legalization of hemp and CBD derived from hemp.
Hemp contains cannabinoids, but no THC, meaning hemp does not give users the high associated with marijuana. CBD is another kind of cannabinoid that is present in both strains of Cannabis sativa. It has garnered a significant amount of attention in recent times and is thought to be responsible for many of cannabis’ therapeutic effects, including pain relief.
The turn to CBD is reflective of a mainstream appeal for plant-based indulgence which is driving expansion to more market categories and regions, according to Innova Market Insights research.
As a result, big companies are already courting CBD products that are expected to define this era, with one example being Royal DSM, which recently entered into a commercial partnership with US-based cannabinoid ingredients manufacturer Mile High Labs to develop “unique hemp-derived cannabinoid solutions.”
What You Need to Know (And What We’re Working to Find Out) About Products Containing Cannabis or Cannabis-derived Compounds, Including CBD
The FDA is working to answer questions about the science, safety, and quality of products containing cannabis and cannabis-derived compounds, particularly CBD.
- Cannabis is a plant of the Cannabaceae family and contains more than eighty biologically active chemical compounds. The most commonly known compounds are delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD). THC is the component that produces the “high” associated with marijuana use. Much interest has been seen around CBD and its potential related to health benefits.
- Marijuana is different from CBD. CBD is a single compound in the cannabis plant, and marijuana is a type of cannabis plant or plant material that contains many naturally occurring compounds, including CBD and THC.
- The FDA has approved only one CBD product, a prescription drug product to treat seizures associated with Lennox Gastaut syndrome (LGS), Dravet syndrome (DS), or tuberous sclerosis complex (TSC) in people one year of age and older.
- It is currently illegal to market CBD by adding it to a food or labeling it as a dietary supplement.
- The FDA has seen only limited data about CBD safety and these data point to real risks that need to be considered before taking CBD for any reason.
- Some CBD products are being marketed with unproven medical claims and are of unknown quality.
- The FDA will continue to update the public as it learns more about CBD.
Potential harm, side effects and unknowns
- CBD has the potential to harm you, and harm can happen even before you become aware of it.
- CBD can cause liver injury.
- CBD can affect how other drugs you are taking work, potentially causing serious side effects.
- Use of CBD with alcohol or other drugs that slow brain activity, such as those used to treat anxiety, panic, stress, or sleep disorders, increases the risk of sedation and drowsiness, which can lead to injuries.
- Male reproductive toxicity, or damage to fertility in males or male offspring of women who have been exposed, has been reported in studies of animals exposed to CBD.
- CBD can cause side effects that you might notice. These side effects should improve when CBD is stopped or when the amount used is reduced.
- Changes in alertness, most commonly experienced as somnolence (drowsiness or sleepiness).
- Gastrointestinal distress, most commonly experienced as diarrhea and/or decreased appetite.
- Changes in mood, most commonly experienced as irritability and agitation.
- There are many important aspects about CBD that we just don’t know, such as:
- What happens if you take CBD daily for sustained periods of time?
- What level of intake triggers the known risks associated with CBD?
- How do different methods of consumption affect intake (e.g., oral consumption, topical , smoking or vaping)?
- What is the effect of CBD on the developing brain (such as on children who take CBD)?
- What are the effects of CBD on the developing fetus or breastfed newborn?
- How does CBD interact with herbs and other plant materials?
- Does CBD cause male reproductive toxicity in humans, as has been reported in studies of animals?
Unanswered questions about the science, safety, and quality
You may have noticed that cannabidiol (CBD) seems to be available almost everywhere, and marketed as a variety of products including drugs, food, dietary supplements, cosmetics, and animal health products. Other than one prescription drug product to treat seizures associated with Lennox Gastaut syndrome (LGS), Dravet syndrome (DS), or tuberous sclerosis complex (TSC) in people one year of age and older, the U.S. Food and Drug Administration (FDA) has not approved any other CBD products, and there is very limited available information about CBD, including about its effects on the body.
The FDA recognizes the significant public interest in cannabis and cannabis-derived compounds, particularly CBD. However, there are many unanswered questions about the science, safety, and quality of products containing CBD. The agency is working on answering these questions through ongoing efforts including feedback from a recent FDA hearing and information and data gathering through a public docket.
Despite the 2018 Farm Bill removing hemp — defined as cannabis and cannabis derivatives with very low concentrations (no more than 0.3% on a dry weight basis) of THC — from the definition of marijuana in the Controlled Substances Act, CBD products are still subject to the same laws and requirements as FDA-regulated products that contain any other substance.
The FDA is concerned that people may mistakenly believe that using CBD “can’t hurt.” The agency wants to be clear that we have seen only limited data about CBD’s safety and these data point to real risks that need to be considered. As part of the drug review and approval process for the prescription drug containing CBD, it was determined that the risks are outweighed by the benefits of the approved drug for the particular population for which it was intended. Consumer use of any CBD products should always be discussed with a healthcare provider. Consumers should be aware of the potential risks associated with using CBD products. Some of these can occur without your awareness, such as:
- Liver Injury: During its review of the marketing application for Epidiolex — a purified form of CBD that the FDA approved in 2018 for use in the treatment of two rare and severe seizure disorders — the FDA identified certain safety risks, including the potential for liver injury. This serious risk can be managed when an FDA-approved CBD drug product is taken under medical supervision, but it is less clear how it might be managed when CBD is used far more widely, without medical supervision, and not in accordance with FDA-approved labeling. Although this risk was increased when taken with other drugs that impact the liver, signs of liver injury were seen also in patients not on those drugs. The occurrence of this liver injury was identified through blood tests, as is often the case with early problems with the liver. Liver injury was also seen in other studies of CBD in published literature. We are concerned about potential liver injury associated with CBD use that could go undetected if not monitored by a healthcare provider.
- Drug Interactions: Information from studies of the FDA-approved CBD drug Epidiolex show that there is a risk of CBD impacting other medicines you take – or that other medicines you take could impact the dose of CBD that can safely be used. Taking CBD with other medications may increase or decrease the effects of the other medications. This may lead to an increased chance of adverse effects from, or decreased effectiveness of, the other medications. Drug interactions were also seen in other studies of CBD in published literature. We are concerned about the potential safety of taking other medicines with CBD when not being monitored by a healthcare provider. In addition, there is limited research on the interactions between CBD products and herbs or other plant-based products in dietary supplements. Consumers should use caution when combining CBD products with herbs or dietary supplements.
- Male Reproductive Toxicity: Studies in laboratory animals showed male reproductive toxicity, including in the male offspring of CBD-treated pregnant females. The changes seen include decrease in testicular size, inhibition of sperm growth and development, and decreased circulating testosterone, among others. Because these findings were only seen in animals, it is not yet clear what these findings mean for human patients and the impact it could have on men (or the male children of pregnant women) who take CBD. For instance, these findings raise the concern that CBD could negatively affect a man’s fertility. Further testing and evaluation are needed to better understand this potential risk.
In addition, CBD can be the cause of side effects that you might notice. These side effects should improve when CBD is stopped or when the amount used is reduced. This could include changes in alertness, most commonly experienced as somnolence (sleepiness), but this could also include insomnia; gastrointestinal distress, most commonly experienced as diarrhea and/or decreased appetite but could also include abdominal pain or upset stomach; and changes in mood, most commonly experienced as irritability and agitation.
The FDA is actively working to learn more about the safety of CBD and CBD products, including the risks identified above and other topics, such as:
- Cumulative Exposure: The cumulative exposure to CBD if people access it across a broad range of consumer products. For example, what happens if you eat food with CBD in it, use CBD-infused skin cream and take other CBD-based products on the same day? How much CBD is absorbed from your skin cream? What if you use these products daily for a week or a month?
- Special Populations: The effects of CBD on other special populations (e.g., the elderly, children, adolescents, pregnant and lactating women).
- CBD and Animals: The safety of CBD use in pets and other animals, including considerations of species, breed, or class and the safety of the resulting human food products (e.g., meat milk, or eggs) from food-producing species.
Unproven medical claims, unsafe manufacturing practices
Some CBD Products are Being Marketed with Unproven Medical Claims and Could be Produced with Unsafe Manufacturing Practices
Unlike the FDA-approved CBD drug product, unapproved CBD products, which could include cosmetics, foods, products marketed as dietary supplements, and any other product (other than Epidiolex) making therapeutic claims, have not been subject to FDA evaluation regarding whether they are effective to treat a particular disease or have other effects that may be claimed. In addition, they have not been evaluated by the FDA to determine what the proper dosage is, how they could interact with other drugs or foods, or whether they have dangerous side effects or other safety concerns.
Misleading, unproven, or false claims associated with CBD products may lead consumers to put off getting important medical care, such as proper diagnosis, treatment, and supportive care. For that reason, it’s important to talk to your doctor about the best way to treat diseases or conditions with available FDA-approved treatment options.
In addition to safety risks and unproven claims, the quality of many CBD products may also be in question. The FDA is also concerned that a lack of appropriate processing controls and practices can put consumers at additional risks. For example, the agency has tested the chemical content of cannabinoid compounds in some of the products, and many were found to not contain the levels of CBD they claimed. We are also investigating reports of CBD potentially containing unsafe levels of contaminants (e.g., pesticides, heavy metals, THC).
CBD products are also being marketed for pets and other animals. The FDA has not approved CBD for any use in animals and the concerns regarding CBD products with unproven medical claims and of unknown quality equally apply to CBD products marketed for animals. The FDA recommends pet owners talk with their veterinarians about appropriate treatment options for their pets.
The FDA’s top priority is to protect the public health. This priority includes making sure consumers know about products that put their health and safety at greatest risk, such as those claiming to prevent, diagnose, treat, mitigate, or cure serious diseases. For example, the agency has warned companies to stop selling CBD products they claim are intended to prevent, diagnose, treat, mitigate, or cure serious diseases such as cancer, Alzheimer’s disease, psychiatric disorders and diabetes. While we have focused on these types of products, we will continue to monitor the marketplace for any product that poses a risk to public health, including those with dangerous contaminants, those marketed to vulnerable populations, and products that otherwise put the public health at risk.
Evaluation of the regulatory frameworks
The FDA is Continuing to Evaluate the Regulatory Frameworks for Products Containing Cannabis and Cannabis-Derived Compounds
The FDA continues to believe the drug approval process represents the best way to ensure that safe and effective new medicines, including any drugs derived from cannabis, are available to patients in need of appropriate medical therapy. The agency is committed to supporting the development of new drugs, including cannabis and cannabis-derived drugs, through the investigational new drug and drug approval process.
We are aware that there may be some products on the market that add CBD to a food or label CBD as a dietary supplement. Under federal law, it is illegal to market CBD this way.
The FDA is evaluating the regulatory frameworks that apply to certain cannabis-derived products that are intended for non-drug uses, including whether and/or how the FDA might consider updating its regulations, as well as whether potential legislation might be appropriate. The information we have underscores the need for further study and high quality, scientific information about the safety and potential uses of CBD.
The FDA is committed to setting sound, science-based policy. The FDA is raising these safety, marketing, and labeling concerns because we want you to know what we know. We encourage consumers to think carefully before exposing themselves, their family, or their pets, to any product, especially products like CBD, which may have potential risks, be of unknown quality, and have unproven benefits.
Our Consumer Update includes a practical summary of what we know to date. As we learn more, our goal is to update you with the information you need to make informed choices about CBD products. Also, as the regulatory pathways are clarified we will take care to inform all stakeholders as quickly as possible.