cbd oil for cushing’s syndrome

Can Medical Cannabis Help Humans and Pets with Cushing’s Disease?

Cushing’s disease is a disorder of the endocrine system of the body. The disease is also called hypercortisolism hyperadrenocorticism.

It causes excess production of a hormone called Cortisol. Cortisol is produced by the adrenal glands when the body faces a stressful situation, such as an external threat or an internal problem.

Cortisol also helps with the control of the weight and amount of sugar present in the blood. In normal conditions, the hormone adjusts a body’s metabolism and immune system to cope up with the stress.

However, when the body produces excessive amounts of Cortisol, it can cause several health problems and affect the muscles, skin, bones, and vital organs.

It also opens the doors for other medical complications like diabetes, weight gain, and mood swings.

The disease can affect humans as well as animals like dogs and cats. Cushing’s disease can be caused by a tumor on the adrenal or pituitary glands, or an overuse of steroid laden medicines.

The treatment of the disease can be complicated and expensive. The medications can also cause side effects which are worse than the symptoms of the disease.

Medications for Cushing’s disease also require regular blood work for the rest of the life to make sure that the medicines are working as desired.

That is why many doctors, patients, and pet parents are exploring alternative medications for ailments, such as Cushing’s disease.

CBD oil or Cannabidiol is creating a lot of waves in the healthcare industry these days. Experts claim that CBD oil can be used to treat or subdue many complicated diseases without the nasty side effects of regular medicines.

Although the healthcare experts are divided in their opinions about the certainty of treatment, CBD oil is gaining popularity as human as well as animal medications.

In this article, we are going to discuss if there are scientific benefits of using Cannabis-based medicines to provide relief to human patients and pets.

Cannabinoid Reception on the Endocrine System

Cushing’s The effects of cannabinoids, such as CBD and THC, are dependent on the link between the endocannabinoid system and the endocrine system.

Experts have shown proof that there are cannabinoid receptor cells present all over the endocrine system.

The receptors play a vital role in the response to stress and changes in the hypothalamic and pituitary glands. Activating these receptors with the aid of CBD or THC can have a significant improvement for the hormonal balance in the body.

Adrenal support provided by cannabis-based medication can reduce the production of aldosterone on the outer levels of the adrenal glands. Aldosterone is a hormone that helps the body in balancing the levels of electrolytes.

Adrenal support can also control the overproduction of sex hormones like estrogen or testosterone from the inner layers of the adrenal glands.

Cannabis-based medicines have shown clear indications of affecting the body’s response to stress, their sleep cycle, metabolism, and regulation of hormones.

The adrenal support for dogs , cats, and humans can also reduce the chances of tumor formation on the glands.

Research has shown that Cannabidiol and THC can have direct influences on the creation of Cortisol in the body.

The research suggested that although there were negligible effects on the growth hormones, the Cortisol levels were significantly affected.

CBD affected the receptors in the pancreas, which regulated the insulin levels, which can be useful to treat diabetes caused by Cushing’s disease.

Cannabidiol Reduces Stress

We are all aware of the effects of THC on the human body and its ability to reduce anxiety. CBD can have similar effects on a pet’s stress levels too.

It impacts the 5-HT1a receptors that are responsible for increasing the signals of serotonin generation in the brain.

The increase of serotonin in the body can induce happy feelings and reduce stress, and the production of Cortisol in the body.

CBD, if administered at night, can help in regulating the natural body clock by stimulating particular cells of the pineal gland and increasing the melatonin levels in the body.

CBD can increase the signals to other neurotransmitters, such as Gamma-Aminobutyric acid ( GABA) that can cause calming effects on a body.

Cannabidiol also increases the levels of anandamide. Anandamide is an endocannabinoid that can have a calming effect and create a feeling of bliss.

All these hormones and neurotransmitters are directly related to the secretion of Cortisol, and the reduction of stress can cause effects of relief in the body.

These researches can be indicators of the positive effects of administering CBD medications to humans and pets suffering from Cushing’s disease.

Do Patients and Pet Parents Use CBD Medications for Cushing’s Disease?

As we mentioned before, the healthcare experts are divided in their research and affirmation of the positive effects of CBD on a human or a pet suffering from Cushing’s disease.

However, many patients and pet parents have tried CBD medicines and seen positive results.

Both humans and pets have responded well to the medication with a significant increase in appetite, energy, and stamina. In many cases, pets’ skin and fur have shown notable improvement.

The pets have shown a much better response to CBD medications than regular medicines, without any side effects.

There are numerous testimonials by pet parents on the websites selling CBD medication for Cushing’s disease.

Common ways of curing Cushing’s illness

The traditional therapy of dealing with Cushing’s illness is surgery to eliminate all tumors. On the other hand, doctors might even prescribe other therapies.

However, surgery might be risky, particularly for older pets. Moreover, medications could lead to extra bad impacts.

Besides, some natural choices could offer a lovely dog some comfort without worrying about any stress and liver-ruining medications.

Other researchers claimed that CBD could inhibit the dangerous cells’ development in mice for bladder cancer.

Moreover, it can avoid other tumors in the future. The outcome of this research recognized that CBD might be a feasible choice to tackle a lot of tumors for either pets or people.

Besides, CBD could operate to deal with the imbalance that might be leading to different tumors in the initial area. On the other hand, the CBD could adjust the hormonal imbalance for Cushing’s adrenal.

Another research carried out by Illinois University proved that cannabinoid exposure might get some profound impacts on the stress axis’s function. Also, the seed oil consists of the fatty acids’ balance.

Last but not least, the most crucial solution to deal with Cushing’s illness is through oral tincture for a lot of active CBD.

CBD Oil For Dogs & Cats With Cushings Syndrome

Adrenal gland disorders such as Cushing’s syndrome in cats and dogs are hard to diagnose. The vet may order a series of tests to determine the type of Cushing’s syndrome present in your pets. Understanding Cushing’s syndrome will help you decide when and how to get proper treatment.

If your dog/cat is diagnosed with Cushing’s syndrome, CBD oil might be of help. In this article, we will show you the beneficial effects of CBD oil (hemp oil extract) to your furry friends. We will also explain how hemp oil can treat adrenal gland disorders such as Cushing’s syndrome.

Table of Contents

What Is Cushing’s Syndrome in Dogs and Cats

Also known as hyperadrenocorticism, Cushing’s syndrome is a condition that occurs when there is excessive production of hormones in the adrenal glands. Cushing’s syndrome usually happens in middle-aged and older dogs/cats. The adrenal glands, which are located above the kidneys produce too much cortisol that goes directly into the bloodstream, causing a group of symptoms.

This group of signs and symptoms is called a syndrome. The hormone cortisol regulates many different bodily functions including anti-inflammatory, immunosuppressive, and homeostatic (maintaining balance) functions. Overproduction of cortisol in the adrenal glands results from either pituitary or adrenal gland tumor.

Different Types of Cushing’s Syndrome

The two major types of Cushing’s syndrome in dogs and cats are pituitary-dependent and adrenal-dependent.

  1. Pituitary-Dependent Cushing’s Syndrome

This is the most common type of Cushing’s syndrome in animals, affecting almost 80-90% of the total population of animals with Cushing’s. This is mainly caused by a pea-sized tumor in the pituitary gland, which is located at the base of the brain.

  1. Adrenal-Dependent Cushing’s Syndrome

Adrenal dependent type results from a tumor in one of the adrenal glands. These are a pair of glands located on top of the kidneys. Adrenal dependent Cushing’s syndrome affects 15-20% of diagnosed dogs.

There’s also another type of Cushing’s syndrome that results from chronic steroid use in animals. This is called iatrogenic Cushing’s syndrome.

Symptoms of Cushing’s Syndrome in Cats and Dogs

Diagnosing Cushing’s syndrome in felines and canines can be a little tricky since the manifestation of the disease is similar to diabetes. The most common signs and symptoms of dog/cat hyperadrenocorticism include:

  • Excessive thirst and increased urination
  • Noticeable weight gain, usually around the waist and abdominal area
  • Irritability and agitation
  • Lack of interest and restlessness
  • Poor skin health
  • Bruising and changes in skin pigmentation
  • Decreased bone and muscle mass

Cushing’s syndrome is a chronic and progressive disease – meaning, the initial symptoms are mild or subtle. These will become more noticeable and severe in the following days.

How to Diagnose Cushing’s Syndrome in Cats and Dogs

  1. The Low/High Dexamethasone Suppression Tests
  2. Endogenous ACTH (Acetylcholine) Level
  3. Imaging Tests – Ultrasound, CT-scan, MRI (Magnetic Resonance Imaging)

How to Prevent Cushing’s Syndrome in Dogs and Cats

To prevent the occurrence of Cushing’s syndrome in your favorite pets, do the following:

  1. Give your pets a healthy, and well-balanced diet.
  2. Give them daily supplements such as Vitamins C and D, calcium, and zinc to increase their immunity against diseases.
  3. Do not give foods that contain too much sodium, fats, and sugar.
  4. Avoid things that can give too much stress to your pets.
  5. Regularly visit your vet for immunization, vitamin-mineral supplementation, and general check-up.
  6. Immediately bring your canine or feline to the vet clinic when there are signs and symptoms of Cushing’s disease.

Natural Remedies for Dog and Cat Cushing’s Syndrome

Medical management, which includes medications and treatments, may cause adverse reactions and side effects to your pets. If you’re a fan of natural and organic treatments, check-out the following:

  • Fish Oil

Fish oil is a popular natural treatment for almost all kinds of animal diseases. Increased cortisol production decreases the immunity of cats/dogs that may result in inflammation of the skin. Fish oil is one of the healthier remedies for skin inflammation. There are over-the-counter fish oil capsules that can be given to your dogs. The recommended dose for skin disease is 60-100mg/kg-cap twice a day. Before buying, consult your vet about it.

  • Low-Carb Diet

A low-carb diet can be used as a nutrition management plan for Cushing’s syndrome. Reducing your pet’s carbohydrate intake can help eliminate the signs and symptoms of the disease. Replace grains with potatoes, beans, or peas. For better results, do the preparation yourself.

  • Herbs

Many different herbs are believed to be effective in treating Cushing’s syndrome. Some of these powerful plant herbs include clover, garlic, kelp, nettle, and rosehips.

  • Acupuncture

Acupuncture is a traditional Chinese medicine that can help treat different animal diseases. This oriental medicine works by stimulating different acupressure points to relieve the symptoms of the disease. Acupuncture also helps relieve stress, anxiety, and agitation in dogs and cats. The acupuncture therapy helps regulate the endocrine system and relieves inflammation in your pet’s body.

CBD Oil for Cushing’s Syndrome in Dogs and Cats

The use of Cannabidiol or CBD oil is becoming a popular treatment nowadays. Its health benefits and powerful healing properties have been receiving consistent praises from different parts of the world. CBD oil generated from the hemp plant is mainly used as an analgesic and anti-inflammatory medicine. Cannabidiol contains lower than 0.3% of tetrahydrocannabinol (THC), the active substance of the hemp plant. This amount makes CBD oil not psychoactive and safe to use.

CBD oil directly affects the endocannabinoid receptors that maintain homeostasis or balance in the body. Cannabidiol is also believed to have a direct effect on the secretion of cortisol. The Brazilian Journal of Medical and Biological Research examined the effect of CBD on cortisol levels of humans. They found out that CBD oil can lower the production of cortisol in the blood. Today, CBD oil is constantly being used in veterinary medicine as a treatment for different animal diseases.

CBD Oil Dosage for Cat/Dog Cushing’s Syndrome

The standard initial dosage of CBD oil for Cushing’s syndrome is 0.2 mg/kg twice a day. For pain and inflammation, you can increase the dosage to 2-3 mg/kg twice daily. If you find it difficult to calculate the dosage, you can refer to this dosage chart.

CBD oil is considered a wonder drug that can treat almost all kinds of animal disease symptoms. If you think your furry friends have signs and symptoms of Cushing’s syndrome, or if they’ve already been diagnosed with this adrenal gland disorder, you can consider CBD oil as an alternative treatment. But always remember, your veterinarian’s advice is still the best treatment for Cushing’s syndrome.